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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVDFHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIV
LCTNTMHKVADAIESRCTLPFLHIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQI
IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGSTEIGLLVPEERSVLPVFDTAAIHAEDAVAFMLSLEHHH

The query sequence (length=235) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5elm:B 235 235 1.0000 1.0000 1.0000 3.70e-176 5elm:C, 5elm:D, 5hra:A, 5hra:B, 5hrc:A, 5hrc:B
2 3ojc:A 230 229 0.5702 0.5826 0.5852 7.26e-99 3ojc:B
3 2dx7:A 228 229 0.2298 0.2368 0.2358 8.54e-15
4 3s7z:B 235 150 0.2043 0.2043 0.3200 2.50e-07
5 6dli:A 256 83 0.0979 0.0898 0.2771 0.59 6dli:B, 6dli:C, 6dli:D, 5w16:A, 5w16:B, 5w16:C, 5w16:D
6 6cl6:A 364 85 0.1064 0.0687 0.2941 1.1 6cl6:B, 6cl6:C, 6cl6:D, 6cl6:E, 6cl6:F, 6cu2:A
7 5ijw:B 276 80 0.1021 0.0870 0.3000 2.4 5ijw:A
8 3oaj:A 310 59 0.0809 0.0613 0.3220 2.7 3oaj:B
9 6mgr:C 369 45 0.0681 0.0434 0.3556 3.5 6mgr:A, 6mgr:B, 6mgr:D, 4mz1:A, 4mz1:B, 4mz1:C, 4mz8:A, 4mz8:B, 4mz8:C, 4mz8:D, 4r7j:A, 5uqf:A, 5uqf:B, 5uqf:C, 5uqg:A, 5uqg:B, 5uqg:H, 5uqg:C, 5uqg:G, 5uqg:D, 5uqg:E, 5uqg:F, 5uqh:A, 5uqh:B, 5uqh:C, 5uqh:D, 5uqh:E, 5uqh:F, 5uqh:G, 5uqh:H, 5urq:A, 5urq:D, 5urq:B, 5urq:C, 5urq:E, 5urq:H, 5urq:F, 5urq:G
10 4tpn:A 386 52 0.0809 0.0492 0.3654 4.3
11 5d3u:A 403 52 0.0809 0.0471 0.3654 4.7 5d3u:B, 5d40:A, 5d40:B, 4l36:A, 4l36:B, 4tpo:A
12 3t5n:A 282 25 0.0468 0.0390 0.4400 5.7
13 3t5q:G 303 25 0.0468 0.0363 0.4400 6.0 3t5q:B, 3t5q:E, 3t5q:I, 3t5q:K
14 5bqf:A 317 60 0.0809 0.0599 0.3167 6.2 5tsd:A, 5tsd:B, 4xcv:A
15 3mx2:B 517 25 0.0468 0.0213 0.4400 8.0 4fvu:A, 4g9z:A, 4gv3:A, 4gv6:A, 4gv9:A, 3mwp:A, 3mwp:B, 3mwp:C, 3mwt:A, 3mwt:B, 3mwt:C, 3mx2:A, 3mx2:C, 3mx5:A, 3mx5:B, 3mx5:C, 3q7b:A, 3q7c:A, 3r3l:A, 3r3l:B, 3r3l:C, 3t5q:A, 7v37:A, 7v37:B, 7v38:A, 7v38:B, 7v39:A, 7v39:B, 7v3a:A, 7v3a:B, 7v3b:A, 7v3b:B, 7v3c:A, 7v3c:B
16 3e0q:C 285 35 0.0340 0.0281 0.2286 8.3 3djf:A, 3djf:B, 3djf:C, 3e0q:A, 3e0q:B, 3e9r:B, 3e9z:A, 3e9z:C, 3f8w:A, 3f8w:B, 3f8w:C, 3faz:A, 3faz:B, 3faz:C, 3fb1:A, 3fb1:B, 3fb1:C, 3fnq:A, 3fnq:B, 3fnq:C, 3iex:A, 3iex:C, 1tcu:A, 1tcu:B, 1tcu:C, 1tcv:A, 1tcv:B, 1tcv:C, 1td1:A, 1td1:B, 1td1:C
17 3fwz:A 140 43 0.0596 0.1000 0.3256 8.3 3fwz:B
18 5hev:F 210 20 0.0511 0.0571 0.6000 9.2 5hev:A, 5hev:B, 5hev:C
19 6q2p:B 293 69 0.0681 0.0546 0.2319 9.2 6q2p:A, 6q2q:A, 6q2q:B, 5vsl:A, 5vsl:B, 5vsm:A, 5vsm:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218