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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKRYVVGISGASGIVLAVTLVSELARLGHHIDVIISPSAQKTLYYELDTKSFLSTIPQNFHNQIVLHHISSIESSVSSGS
NTIDATIIVPCSVATVAAISCGLADNLLRRVADVALKEKRPLILVPREAPLSAIHLENLLKLAQNGAVILPPMPIWYFKP
QTAEDIANDIVGKILAILQLDSPLIKR

The query sequence (length=187) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7km3:F 190 187 1.0000 0.9842 1.0000 7.28e-135 7km2:L, 7km2:D, 7km2:I, 7km2:A, 7km2:B, 7km2:K, 7km2:C, 7km2:E, 7km2:J, 7km2:F, 7km2:G, 7km2:H, 7km3:L, 7km3:D, 7km3:I, 7km3:A, 7km3:B, 7km3:G, 7km3:K, 7km3:C, 7km3:E, 7km3:H, 7km3:J
2 6m8v:A 183 186 0.4118 0.4208 0.4140 2.86e-46
3 6qlg:A 188 187 0.4064 0.4043 0.4064 8.94e-44 6qlg:C, 6qlg:B, 6qlg:E, 6qlg:D, 6qlg:F
4 6qlh:A 208 195 0.3957 0.3558 0.3795 1.08e-40 6qli:A, 6qlj:A, 6qlk:A, 6qll:A, 6qlv:A, 6qlv:B, 6qlv:C, 6qlv:D, 6qlv:H, 6qlv:E, 6qlv:F, 6qlv:K, 6qlv:G, 6qlv:I, 6qlv:J, 6qlv:L, 4zaf:A, 4zag:A, 4zal:A, 4zan:A, 4zav:A, 4zaw:A, 4zax:A, 4zay:A, 4zaz:A, 3zqu:A
5 1sbz:D 185 190 0.3904 0.3946 0.3842 1.53e-38 1sbz:A, 1sbz:B, 1sbz:C
6 6m8t:A 189 173 0.3583 0.3545 0.3873 1.01e-37 6m8u:A
7 4rhe:B 203 194 0.3529 0.3251 0.3402 7.75e-33 4rhe:A, 4rhe:E, 4rhe:C, 4rhe:D, 4rhe:F
8 6tgv:C 389 154 0.2193 0.1054 0.2662 1.64e-04 8ow5:A, 8ow5:B, 8ow5:C, 8ow5:D, 8owb:A, 8owb:B, 8owb:C, 8owb:D, 8owp:A, 8owp:B, 8owp:C, 8owp:D, 8owq:A, 8owq:B, 8owq:C, 8owq:D, 8owr:A, 8owr:C, 8owr:D, 4qji:A, 4qji:B, 6tgv:A, 6tgv:B, 6tgv:D, 6th2:A, 6th2:C, 6thc:A, 6thc:B, 6thc:C, 6thc:D
9 1e20:A 185 76 0.1283 0.1297 0.3158 0.097 1mvl:A, 1mvn:A
10 3qjg:A 171 96 0.1337 0.1462 0.2604 0.46 3qjg:C, 3qjg:B, 3qjg:D, 3qjg:E, 3qjg:F, 3qjg:G, 3qjg:I, 3qjg:H, 3qjg:J, 3qjg:L, 3qjg:K
11 1g5q:A 174 110 0.1283 0.1379 0.2182 1.0 1g5q:D, 1g5q:G, 1g5q:L, 1g63:A, 1g63:B, 1g63:H, 1g63:C, 1g63:J, 1g63:D, 1g63:F, 1g63:E, 1g63:G, 1g63:I, 1g63:L, 1g63:K
12 8a8h:B 146 64 0.0909 0.1164 0.2656 1.4
13 4zcf:C 627 37 0.0642 0.0191 0.3243 2.0
14 1kq3:A 364 137 0.2139 0.1099 0.2920 2.5
15 5o9z:L 459 48 0.0802 0.0327 0.3125 2.8
16 5dzk:N 179 53 0.0856 0.0894 0.3019 3.3 5dzk:H, 5dzk:I, 5dzk:J, 5dzk:K, 5dzk:L, 5dzk:M, 5dzk:h, 5dzk:i, 5dzk:j, 5dzk:k, 5dzk:l, 5dzk:m, 5dzk:n, 6iw7:B, 6iw7:K, 6iw7:M, 6iw7:D, 6iw7:I, 6iw7:N, 6iw7:G, 4u0g:H, 4u0g:I, 4u0g:J, 4u0g:K, 4u0g:L, 4u0g:M, 4u0g:N, 4u0g:V, 4u0g:W, 4u0g:X, 4u0g:Y, 4u0g:Z, 4u0g:a, 4u0g:b, 6vgq:N, 6vgq:H, 6vgq:I, 6vgq:J, 6vgq:K, 6vgq:L, 6vgq:M, 7x8x:K, 7x8x:B, 7x8x:M, 7x8x:D, 7x8x:I, 7x8x:G, 7x8x:N, 7x8x:W, 7x8x:P, 7x8x:Y, 7x8x:R, 7x8x:U, 7x8x:b, 7x8x:Z
17 8xme:A 1176 30 0.0642 0.0102 0.4000 3.4 7eu0:A, 8xmb:A, 8xmc:A, 8xmd:A
18 7pjx:x 522 75 0.0909 0.0326 0.2267 3.5
19 2am1:A 454 74 0.1070 0.0441 0.2703 3.6 2am2:A, 3zm5:A, 3zm6:A
20 8fac:A 1377 90 0.1283 0.0174 0.2667 4.1 8e04:A
21 3ia7:A 397 30 0.0642 0.0302 0.4000 4.3 3ia7:B
22 7mjy:A 448 112 0.1444 0.0603 0.2411 5.1 7mjv:A, 7mjw:A, 7mjw:B, 7mjx:B, 7mjx:A, 7mjz:A
23 3v99:B 639 56 0.0856 0.0250 0.2857 5.3
24 5x7o:A 1247 59 0.1070 0.0160 0.3390 5.5 5x7o:B, 5x7p:B, 5x7p:A, 5x7q:A, 5x7q:B, 5x7r:A, 5x7r:B, 5x7s:A, 5x7s:B
25 5yh1:A 439 90 0.1176 0.0501 0.2444 5.6
26 6fqy:A 468 46 0.0695 0.0278 0.2826 5.9 6fqy:B, 6fqz:A, 6fqz:B
27 6q8j:A 188 48 0.0802 0.0798 0.3125 7.8
28 4a8x:C 125 30 0.0535 0.0800 0.3333 8.7
29 6ncf:B 676 56 0.0856 0.0237 0.2857 9.4 6ncf:A, 6ncf:C, 6ncf:D, 3o8y:A, 3o8y:B, 7ttk:A, 7ttk:B, 7ttl:A, 7ttl:D, 3v92:B, 3v92:A, 3v98:A, 3v98:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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