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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKRRRCGVCEVCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCPNLAVKEADDDEEADDDVSEMPSPKKLHQGKKKKQN
KDRISWLGQPMKIEENRTYYQKVSIDEEMLEVGDCVSVIPDDSSKPLYLARVTALWEDKNGQMMFHAHWFCAGTDTVLGA
TSDPLELFLVGECENMQLSYIHSKVKVIYKAPSENWAMEGGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLSCIRL
AELRQKEMPKVLEQIEEVDGRVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKVASPVKRPKKDPVNETLYPEHYRKYSDY
IKGSNLDAPEPYRIGRIKEIHCGKKKGKVNEADIKLRLYKFYRPENTHRSYNGSYHTDINMLYWSDEEAVVNFSDVQGRC
TVEYGEDLLESIQDYSQGGPDRFYFLEAYNSKTKNFEDPPNHARSPGNKGKGLPKLRTLDVFSGCGGLSEGFHQAGISET
LWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKLVMAGEVTNSLGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKF
KNSLVVSFLSYCDYYRPRFFLLENVRNFVSYRRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEK
LPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEIQNGASNSEIPYNGEPLSWFQRQLRGS
HYQPILRDHICKDMSPLVAARMRHIPLFPGSDWRDLPNIQVRLGDGVIAHKLQYTFHDVKNGYSSTGALRGVCSCAEGKA
CDPESRQFSTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDSYR
FFGNILDRHRQVGNAVPPPLAKAIGLEIKLCLLS

The query sequence (length=914) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3pt6:B 915 916 0.9967 0.9956 0.9945 0.0 4da4:A, 3pt6:A, 6w8v:A
2 3av4:A 1140 913 0.9464 0.7588 0.9474 0.0 3av5:A, 3av6:A, 4da4:B, 5gut:A, 5guv:A, 3pt9:A, 6w8v:B, 6w8w:A, 6w8w:B, 5wy1:A
3 3swr:A 965 929 0.8589 0.8135 0.8450 0.0
4 4wxx:B 1178 927 0.8435 0.6545 0.8317 0.0 3epz:A, 3epz:B, 7lmk:A, 7lmk:B, 7lmk:C, 7lmk:D, 7lmm:A, 7lmm:B, 7lmm:C, 7lmm:D, 3pta:A, 7sfc:A, 7sfd:A, 7sfe:A, 7sff:A, 7sfg:A, 5wvo:C, 4wxx:A, 6x9i:A, 6x9j:A, 6x9k:A, 7xi9:A, 7xib:A, 5ydr:B, 4yoc:A
5 7ubu:A 708 399 0.1389 0.1794 0.3183 6.59e-50 4ft4:A, 4ft4:B
6 7ubu:A 708 128 0.0361 0.0466 0.2578 2.74e-04 4ft4:A, 4ft4:B
7 7ubu:A 708 62 0.0263 0.0339 0.3871 0.002 4ft4:A, 4ft4:B
8 4fsx:A 680 397 0.1335 0.1794 0.3073 5.69e-45 4fsx:B, 4ft2:B, 4ft2:A
9 4fsx:A 680 128 0.0361 0.0485 0.2578 3.32e-04 4fsx:B, 4ft2:B, 4ft2:A
10 4fsx:A 680 62 0.0263 0.0353 0.3871 0.002 4fsx:B, 4ft2:B, 4ft2:A
11 9baq:A 1001 477 0.1411 0.1289 0.2704 1.53e-32
12 9baz:A 965 477 0.1433 0.1358 0.2746 8.51e-31 9bap:A
13 10mh:A 327 185 0.0536 0.1498 0.2649 6.83e-11 2c7o:A, 2c7p:A, 2c7q:A, 2c7r:A, 5ciy:A, 3eeo:A, 1fjx:A, 1hmy:A, 2hmy:B, 2hr1:A, 2i9k:A, 1m0e:A, 1mht:A, 3mht:A, 4mht:A, 5mht:A, 6mht:A, 7mht:A, 8mht:A, 9mht:A, 1skm:A, 1svu:B, 2uyc:A, 2uyh:A, 2uz4:A, 2z6a:A, 2z6q:A, 2z6u:A, 2zcj:A
14 10mh:A 327 60 0.0219 0.0612 0.3333 0.048 2c7o:A, 2c7p:A, 2c7q:A, 2c7r:A, 5ciy:A, 3eeo:A, 1fjx:A, 1hmy:A, 2hmy:B, 2hr1:A, 2i9k:A, 1m0e:A, 1mht:A, 3mht:A, 4mht:A, 5mht:A, 6mht:A, 7mht:A, 8mht:A, 9mht:A, 1skm:A, 1svu:B, 2uyc:A, 2uyh:A, 2uz4:A, 2z6a:A, 2z6q:A, 2z6u:A, 2zcj:A
15 3ubt:Y 328 201 0.0525 0.1463 0.2388 1.49e-09 1dct:A, 1dct:B, 3ubt:B, 3ubt:A
16 3ubt:Y 328 53 0.0274 0.0762 0.4717 5.83e-06 1dct:A, 1dct:B, 3ubt:B, 3ubt:A
17 4o64:A 116 68 0.0339 0.2672 0.4559 2.35e-09 4o64:B, 4o64:C
18 4bbq:A 111 69 0.0350 0.2883 0.4638 6.78e-09 4bbq:B
19 6asb:F 85 29 0.0208 0.2235 0.6552 5.07e-07
20 6asb:I 121 29 0.0208 0.1570 0.6552 1.18e-06 6asb:C, 6asb:L
21 2j2s:A 72 45 0.0274 0.3472 0.5556 2.81e-05 2jyi:A, 2kkf:A, 4nw3:A
22 8ds8:A 166 79 0.0219 0.1205 0.2532 8.42e-05 8ds8:B
23 1svu:A 307 185 0.0481 0.1433 0.2378 9.45e-05
24 1svu:A 307 60 0.0219 0.0651 0.3333 0.040
25 3qmb:A 54 50 0.0252 0.4259 0.4600 1.41e-04 3qmc:A, 3qmd:A, 3qmg:A, 3qmh:A, 3qmi:A
26 6vil:D 156 124 0.0317 0.1859 0.2339 1.76e-04 6vil:C, 6vil:B, 6vil:E, 6vil:G
27 1g55:A 313 194 0.0492 0.1438 0.2320 2.86e-04
28 5w9q:A 56 49 0.0219 0.3571 0.4082 4.05e-04 5w9q:B
29 8c56:A 388 118 0.0350 0.0825 0.2712 0.001 8c57:A, 8c58:A, 8c59:A, 4dkj:A
30 6fdf:A 325 183 0.0449 0.1262 0.2240 0.003 6fdf:B, 6fdf:C, 6fdf:D
31 6asd:C 45 50 0.0263 0.5333 0.4800 0.011
32 4h0n:A 331 178 0.0438 0.1208 0.2247 0.012 4h0n:B, 4h0n:C, 4h0n:D
33 4pzi:A 61 54 0.0219 0.3279 0.3704 0.012
34 5z8l:A 204 65 0.0230 0.1029 0.3231 0.026 5z8n:A, 5z8n:B, 5z8n:C
35 5znp:B 186 113 0.0284 0.1398 0.2301 0.16 5znp:A, 5znr:A, 5znr:B
36 7l4c:A 353 121 0.0328 0.0850 0.2479 0.20 7l4f:B, 7l4f:A, 7l4h:A, 7l4k:A, 7l4m:B, 7l4m:A, 7l4n:A, 8t1u:A
37 7cce:A 159 53 0.0153 0.0881 0.2642 0.37
38 9cd7:A 276 66 0.0230 0.0761 0.3182 1.1 8udv:C
39 3qv2:A 320 184 0.0394 0.1125 0.1957 1.8
40 3glf:G 378 58 0.0175 0.0423 0.2759 2.4 8giy:B, 8giy:C, 8giy:D, 8giz:B, 8giz:C, 8giz:D, 8gj0:B, 8gj0:C, 8gj0:D, 8gj1:B, 8gj1:C, 8gj1:D, 8gj2:B, 8gj2:C, 8gj2:D, 8gj3:B, 8gj3:C, 8gj3:D, 3glf:B, 3glf:C, 3glf:D, 3glf:H, 3glf:I, 3glg:B, 3glg:C, 3glg:D, 3glg:G, 3glg:H, 3glg:I, 3gli:B, 3gli:C, 3gli:D, 3gli:G, 3gli:H, 3gli:I, 1jr3:A, 1jr3:B, 1jr3:C, 1njf:A, 1njf:B, 1njf:C, 1njf:D, 1njg:A, 1njg:B, 8val:B, 8val:C, 8val:D, 8vam:B, 8vam:C, 8vam:D, 8vap:B, 8vap:C, 8vap:D, 8vaq:B, 8vaq:C, 8vaq:D, 8var:B, 8var:C, 8var:D, 8vas:B, 8vas:C, 8vas:D, 8vat:B, 8vat:C, 8vat:D, 1xxh:B, 1xxh:C, 1xxh:D, 1xxh:G, 1xxh:H, 1xxh:I, 1xxi:B, 1xxi:C, 1xxi:D, 1xxi:G, 1xxi:H, 1xxi:I
41 8hkx:AS7P 193 24 0.0120 0.0570 0.4583 4.7 8hky:AS7P, 8hkz:AS7P, 8hl1:AS7P, 8hl2:AS7P, 8hl3:AS7P, 8hl4:AS7P, 8hl5:AS7P, 8wkp:AS7P, 8wq2:AS7P, 8wq4:AS7P
42 1pyo:D 99 29 0.0142 0.1313 0.4483 4.9 1pyo:B, 3r5j:D, 3r5j:B, 3r6g:D, 3r6g:B, 3r6l:D, 3r6l:B, 3r7b:D, 3r7n:D, 3r7n:B, 3rjm:B, 3rjm:D
43 1obf:O 335 77 0.0252 0.0687 0.2987 5.1 1obf:P
44 8r5o:I 215 52 0.0219 0.0930 0.3846 5.9 8qma:G, 8r6s:I, 8ras:I, 8rdj:I
45 4wjw:B 673 92 0.0241 0.0327 0.2391 7.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218