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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKPTIALIGRPNVGKSTLFNRLTRDLPGLTRDRHYGHGKVGSKPYFVIDTGGFEHEMAKQTLQAVDEADAVVFLVDGRTG
LTPQDKIIADRLRQSPRPVYLAVNKGEGGDRAVLAAEFYELALGEPHVISGAHGDGVYYLIEEILENFPEADAKHPVFAV
IGRPNVGKSTLVNAILGEKRVIAFIHIDFEREGKPFTIIDTFSVIKAMQAVEAANVAVLVLDAQQDIADQDATIAGFALE
AGRALVVAVNKWDGISEERREQVKRDISRKLYFLDFAKFHFISALKERGIDGLFESIQAAYNAAMIKMPTPKITRVLQTA
VGRQQPPRAGLVRPKMRYAHQGGMNPPVIVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQYNV

The query sequence (length=388) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6xrs:B 392 395 0.9897 0.9796 0.9722 0.0 6xrs:A, 6xrs:D, 6xrs:C
2 3j8g:X 418 419 0.4948 0.4593 0.4582 2.30e-125
3 5dn8:A 405 405 0.4742 0.4543 0.4543 5.02e-123
4 5m7h:A 420 417 0.3969 0.3667 0.3693 6.59e-81 4dcs:A, 4dct:A, 4dcu:A, 2hjg:A, 5mbs:A, 5x4b:A, 5x4b:B
5 1mky:A 407 415 0.3686 0.3514 0.3446 6.08e-63
6 2dyk:A 150 151 0.1289 0.3333 0.3311 2.61e-19 2dyk:B
7 2dyk:A 150 149 0.0979 0.2533 0.2550 7.54e-05 2dyk:B
8 6yxx:EA 532 464 0.2552 0.1861 0.2134 6.49e-17 7aoi:XL, 6yxy:EA
9 7am2:BU 463 386 0.2139 0.1793 0.2150 1.40e-14
10 3ieu:A 293 116 0.1108 0.1468 0.3707 3.64e-12 3ieu:B
11 3ieu:A 293 22 0.0387 0.0512 0.6818 0.004 3ieu:B
12 3geh:A 442 149 0.1186 0.1041 0.3087 7.89e-11
13 3geh:A 442 149 0.1005 0.0882 0.2617 0.001
14 3iev:A 302 176 0.1289 0.1656 0.2841 2.56e-10 7c1o:A, 3r9w:A, 3r9x:A
15 3iev:A 302 232 0.1521 0.1954 0.2543 1.37e-05 7c1o:A, 3r9w:A, 3r9x:A
16 1xzq:A 449 158 0.1211 0.1047 0.2975 5.41e-10 1xzq:B
17 1xzq:A 449 183 0.1366 0.1180 0.2896 9.32e-10 1xzq:B
18 1wf3:A 296 170 0.1289 0.1689 0.2941 1.90e-09
19 1wf3:A 296 100 0.0722 0.0946 0.2800 0.028
20 2gj8:D 172 93 0.0902 0.2035 0.3763 5.43e-08 2gj8:A, 2gj8:B, 2gj8:C, 2gj9:A, 2gj9:B, 2gj9:C, 2gj9:D, 2gja:A, 2gja:B
21 2gj8:D 172 66 0.0644 0.1453 0.3788 0.004 2gj8:A, 2gj8:B, 2gj8:C, 2gj9:A, 2gj9:B, 2gj9:C, 2gj9:D, 2gja:A, 2gja:B
22 1puj:A 261 182 0.1418 0.2107 0.3022 7.34e-07 6ppk:W
23 1puj:A 261 18 0.0335 0.0498 0.7222 1.1 6ppk:W
24 2wjg:A 170 124 0.1005 0.2294 0.3145 3.54e-06 2wjg:B, 2wjh:A, 2wjh:B, 2wji:A, 2wji:B, 2wjj:A, 2wjj:B
25 2wjg:A 170 163 0.1186 0.2706 0.2822 0.003 2wjg:B, 2wjh:A, 2wjh:B, 2wji:A, 2wji:B, 2wjj:A, 2wjj:B
26 8kab:h 430 178 0.1314 0.1186 0.2865 9.14e-05
27 8kab:h 430 69 0.0593 0.0535 0.3333 0.042
28 5kh0:A 363 151 0.1211 0.1295 0.3113 2.13e-04 5kh0:B, 5kh0:C, 5kh0:D
29 3w5j:A 194 55 0.0593 0.1186 0.4182 3.91e-04
30 3i8x:B 261 86 0.0696 0.1034 0.3140 5.35e-04 3hyt:A, 3hyt:B, 3hyt:C, 3i8x:A, 3i8x:C, 4r98:A, 4r98:B
31 3i8x:B 261 48 0.0438 0.0651 0.3542 0.47 3hyt:A, 3hyt:B, 3hyt:C, 3i8x:A, 3i8x:C, 4r98:A, 4r98:B
32 3a1s:A 255 160 0.1160 0.1765 0.2812 0.001 3a1s:B, 3a1t:A, 3a1u:A, 3a1u:B
33 3a1s:A 255 25 0.0335 0.0510 0.5200 0.91 3a1s:B, 3a1t:A, 3a1u:A, 3a1u:B
34 4w2e:y 644 223 0.1546 0.0932 0.2691 0.001
35 8fkt:NB 387 159 0.1160 0.1163 0.2830 0.001 8fkp:NB, 8fku:NB, 8fkv:NB, 8fkw:NB, 8fkx:NB, 8fky:NB, 8fkz:NB, 8fl0:NB, 8ink:u, 8ipd:u, 8ipx:u, 8ipy:u
36 2e87:A 356 210 0.1521 0.1657 0.2810 0.001
37 2e87:A 356 76 0.0696 0.0758 0.3553 0.007
38 7am2:BT 300 180 0.1289 0.1667 0.2778 0.002
39 5ucv:A 187 168 0.1031 0.2139 0.2381 0.002
40 5ucv:A 187 121 0.0799 0.1658 0.2562 0.12
41 2cxx:A 184 183 0.1314 0.2772 0.2787 0.003 2cxx:B, 2cxx:C
42 3kxi:A 326 120 0.0799 0.0951 0.2583 0.003 2qth:A
43 3kxi:A 326 161 0.0954 0.1135 0.2298 2.1 2qth:A
44 7unv:x 593 171 0.1263 0.0826 0.2865 0.004 7unq:x, 7unr:x, 7unt:x, 7unu:x, 7unw:x
45 2qu8:A 194 97 0.0799 0.1598 0.3196 0.004
46 2wib:A 261 82 0.0644 0.0958 0.3049 0.005 2wib:B, 2wic:A
47 2wib:A 261 198 0.1314 0.1954 0.2576 0.061 2wib:B, 2wic:A
48 7btb:m 469 163 0.1005 0.0832 0.2393 0.008 7bt6:m, 6ft6:m, 3jct:m, 6m62:m, 7oh3:m, 7ohq:m, 7oht:m, 7ug6:m, 7uoo:m, 7uqb:m, 7uqz:m, 7uui:m, 7v08:m, 6ylg:m, 6ylh:m
49 3pqc:B 194 170 0.1211 0.2423 0.2765 0.012 3pqc:A
50 3pqc:B 194 27 0.0387 0.0773 0.5556 0.46 3pqc:A
51 1h65:A 257 74 0.0619 0.0934 0.3243 0.014 3bb1:A, 3bb1:B, 3bb1:C, 3bb1:D, 3bb1:E, 3bb1:F, 3bb1:G, 3bb1:H, 1h65:B, 1h65:C
52 3b1v:A 264 114 0.0928 0.1364 0.3158 0.014 3b1w:A, 3b1w:B, 3b1w:C, 3b1w:D, 3b1x:A, 3b1x:B, 3b1y:A, 7bvu:A, 7bvu:B, 7bwv:A, 7bwv:B, 3lx5:A, 3lx8:A, 4non:A, 4non:B, 3ss8:A, 3ss8:B, 3tah:A, 3tah:B
53 6g0z:A 290 126 0.0825 0.1103 0.2540 0.015 6g0z:B, 6g12:A, 6g12:B, 6g14:B, 6g14:A, 6g15:A, 6g15:B
54 6g0z:A 290 65 0.0619 0.0828 0.3692 0.13 6g0z:B, 6g12:A, 6g12:B, 6g14:B, 6g14:A, 6g15:A, 6g15:B
55 5ady:6 426 21 0.0361 0.0329 0.6667 0.025 8g31:6, 8g34:6, 8g38:6, 7yla:6
56 7pua:IA 704 134 0.0979 0.0540 0.2836 0.038 7pub:IA
57 6n8j:m 378 137 0.0799 0.0820 0.2263 0.045
58 8uua:v 418 170 0.1057 0.0981 0.2412 0.049 8a57:D, 8uu7:v, 8uu8:v, 8uu9:v
59 2dby:A 355 39 0.0464 0.0507 0.4615 0.052
60 2dby:A 355 16 0.0284 0.0310 0.6875 6.2
61 7y9i:A 362 20 0.0361 0.0387 0.7000 0.093
62 7y9i:A 362 23 0.0284 0.0304 0.4783 6.9
63 2ohf:A 327 27 0.0412 0.0489 0.5926 0.11
64 6yxy:EQ 471 71 0.0464 0.0382 0.2535 0.12
65 6yxy:EQ 471 140 0.0979 0.0807 0.2714 0.59
66 2lkd:A 178 158 0.0979 0.2135 0.2405 0.17
67 2lkd:A 178 111 0.0696 0.1517 0.2432 0.95
68 5j8b:z 671 239 0.1598 0.0924 0.2594 0.18 5imq:B
69 5t62:W 306 129 0.0851 0.1078 0.2558 0.18
70 5t62:W 306 79 0.0515 0.0654 0.2532 9.1
71 6yxy:EM 330 132 0.1031 0.1212 0.3030 0.25
72 8kie:y 363 20 0.0335 0.0358 0.6500 0.25
73 8kie:y 363 16 0.0284 0.0303 0.6875 7.1
74 6yxx:EM 308 132 0.1031 0.1299 0.3030 0.27
75 1svw:A 190 122 0.0928 0.1895 0.2951 0.29 1svi:A, 1svw:B
76 8ir1:4 620 69 0.0464 0.0290 0.2609 0.30 8fkt:SR, 8fku:SR, 8fkv:SR, 8fkw:SR, 8fkx:SR, 8fky:SR, 8fkz:SR, 8fl0:SR, 8fl2:SR, 8fl3:SR, 8fl6:SR, 8fl7:SR, 8fl9:SR, 8fla:SR, 8flb:SR, 8flc:SR, 8fld:SR, 8fle:SR, 8flf:SR, 8idt:4, 8idy:4, 8ie3:4, 8ine:4, 8inf:4, 8ink:4, 8ipd:4, 8ipx:4, 8ipy:4, 8ir3:4, 6lss:4, 6lu8:4
77 8ir1:4 620 21 0.0309 0.0194 0.5714 1.3 8fkt:SR, 8fku:SR, 8fkv:SR, 8fkw:SR, 8fkx:SR, 8fky:SR, 8fkz:SR, 8fl0:SR, 8fl2:SR, 8fl3:SR, 8fl6:SR, 8fl7:SR, 8fl9:SR, 8fla:SR, 8flb:SR, 8flc:SR, 8fld:SR, 8fle:SR, 8flf:SR, 8idt:4, 8idy:4, 8ie3:4, 8ine:4, 8inf:4, 8ink:4, 8ipd:4, 8ipx:4, 8ipy:4, 8ir3:4, 6lss:4, 6lu8:4
78 8fl4:SR 593 69 0.0464 0.0304 0.2609 0.31 8fkr:SR, 8fks:SR
79 8fl4:SR 593 21 0.0309 0.0202 0.5714 1.3 8fkr:SR, 8fks:SR
80 6qtz:o 325 140 0.0902 0.1077 0.2500 0.34 6qik:o, 6ri5:o, 6rzz:o, 6s05:o
81 8fl2:NC 511 128 0.0825 0.0626 0.2500 0.36 8fkz:NC, 8fl0:NC, 8fl3:NC, 8fl4:NC, 8idt:A, 8idy:A, 8ie3:A, 8ine:A, 8inf:A, 8ink:w, 8ipd:w, 8ipx:w, 8ipy:w, 8ir1:w, 8ir3:w
82 2ywf:A 532 174 0.1263 0.0921 0.2816 0.43 2ywg:A, 2ywh:A
83 6gej:Y 447 53 0.0387 0.0336 0.2830 0.50 8ets:W, 8ets:U, 8ets:Y, 8etu:W, 8etu:U, 8etu:Y, 8etw:W, 8etw:U, 8etw:Y, 8eu9:W, 8eu9:U, 8eu9:Y, 8euf:W, 8euf:U, 8euf:Y, 6gej:U, 6gej:W, 6gen:U, 6gen:W, 6gen:Y
84 8oo7:E 443 81 0.0541 0.0474 0.2593 0.57 8av6:E, 8av6:D, 8av6:F, 6fhs:E, 6fhs:D, 6fhs:F, 6fml:E, 6fml:D, 6fml:F, 8oo7:D, 8oo7:F, 8ooc:D, 8ooc:E, 8ooc:F, 8oop:D, 8oop:E, 8oop:F, 8oor:D, 8oor:E, 8oor:F, 4ww4:B
85 5fm7:B 422 81 0.0541 0.0498 0.2593 0.58
86 8eti:b 391 80 0.0619 0.0614 0.3000 0.58 8esr:b, 8etg:b
87 8eti:b 391 69 0.0490 0.0486 0.2754 0.84 8esr:b, 8etg:b
88 5imr:C 570 172 0.1186 0.0807 0.2674 0.60
89 8etc:b 415 80 0.0619 0.0578 0.3000 0.69 8esq:b, 8etj:b
90 8etc:b 415 69 0.0490 0.0458 0.2754 0.76 8esq:b, 8etj:b
91 8i9w:CL 397 27 0.0361 0.0353 0.5185 0.78 8i9t:CL, 8i9v:CL, 8i9x:CL, 8i9y:CL, 8i9z:CL, 8ia0:CL, 8pv1:CL, 8pv2:CL, 8pv3:CL, 8pv4:CL, 8pv5:CL, 8pv6:CL, 8pv7:CL, 8pv8:CL, 8pvk:CL, 8pvl:CL
92 8i9w:CL 397 18 0.0309 0.0302 0.6667 2.5 8i9t:CL, 8i9v:CL, 8i9x:CL, 8i9y:CL, 8i9z:CL, 8ia0:CL, 8pv1:CL, 8pv2:CL, 8pv3:CL, 8pv4:CL, 8pv5:CL, 8pv6:CL, 8pv7:CL, 8pv8:CL, 8pvk:CL, 8pvl:CL
93 6vs4:A 223 80 0.0644 0.1121 0.3125 0.88 6vs4:B
94 6n8n:W 377 22 0.0284 0.0292 0.5000 1.0 6n8o:W
95 9cc9:A 850 103 0.0619 0.0282 0.2330 1.0 9cc8:A, 9cc8:B, 9cc8:C, 9cc8:D, 9cc8:E, 9cc8:F, 9cc9:B, 9cc9:C, 9cc9:D, 9cc9:E, 9cc9:F, 9cc9:G, 9cc9:H, 9cc9:I, 9cc9:J, 9cc9:K, 9cc9:L
96 3gee:A 427 27 0.0361 0.0328 0.5185 1.1
97 5ee3:B 364 20 0.0309 0.0330 0.6000 1.1 5ee3:A, 5ee9:A
98 5cyp:D 227 50 0.0438 0.0749 0.3400 1.2
99 8csq:a 263 56 0.0490 0.0722 0.3393 1.3
100 8csq:a 263 51 0.0438 0.0646 0.3333 7.2
101 8pv1:Cd 462 136 0.0825 0.0693 0.2353 1.4 8pv2:Cd, 8pv3:Cd, 8pv4:Cd, 8pv5:Cd, 8pv6:Cd, 8pv7:Cd, 8pv8:Cd, 8pvk:Cd, 8pvl:Cd
102 7apd:C 287 43 0.0464 0.0627 0.4186 1.6 5a9k:A, 5a9k:B, 5a9k:C, 7apd:D, 7apd:E, 7apd:F, 7apd:A, 2gxa:B, 2gxa:C, 2gxa:D, 2gxa:E, 2gxa:F, 2gxa:G, 2gxa:H, 2gxa:I, 2gxa:J, 2gxa:K, 2gxa:L, 2gxa:A, 2v9p:A, 2v9p:B, 2v9p:C, 2v9p:H, 2v9p:I
103 3izy:P 537 163 0.1057 0.0764 0.2515 2.0
104 5ub8:A 174 21 0.0335 0.0747 0.6190 2.1
105 6gaw:BC 571 140 0.0928 0.0630 0.2571 2.2 6gaz:BC, 6gb2:BC, 7po2:7, 8qrn:7, 6rw5:7
106 7pd3:z 311 62 0.0593 0.0740 0.3710 2.3 8pk0:z, 8qsj:z
107 7pd3:z 311 19 0.0284 0.0354 0.5789 6.4 8pk0:z, 8qsj:z
108 8xuq:A 885 116 0.0773 0.0339 0.2586 2.3 8xuo:A, 8xuo:G, 8xuq:E, 8xuq:F, 8xuq:G, 8xuv:A, 8xuv:B, 8xuv:C, 8xuv:D, 8xuv:E, 8xuv:F, 8xuv:G, 8xuv:H, 8xuv:I, 8xuv:J, 8xuv:K, 8xuv:L
109 7of4:C 422 23 0.0284 0.0261 0.4783 2.4 7of2:C, 7of6:C
110 7of4:C 422 89 0.0644 0.0592 0.2809 3.0 7of2:C, 7of6:C
111 4zu9:A 582 170 0.1057 0.0704 0.2412 2.9
112 3bfk:B 179 21 0.0335 0.0726 0.6190 3.0 3bfk:A, 3bfk:C, 3bfk:D, 3bfk:E
113 8rfh:A 730 111 0.0696 0.0370 0.2432 3.1 8rfh:B
114 2j3e:A 249 78 0.0593 0.0924 0.2949 3.9 3bb3:A, 3bb4:A, 3def:A
115 1zun:B 394 145 0.1005 0.0990 0.2690 3.9
116 1lnz:A 342 174 0.1160 0.1316 0.2586 4.2 1lnz:B
117 7o9k:C 255 19 0.0284 0.0431 0.5789 5.0 7o9m:C
118 7o9k:C 255 34 0.0412 0.0627 0.4706 5.6 7o9m:C
119 5cyp:A 248 49 0.0515 0.0806 0.4082 5.2 5cyp:B, 5cyp:C
120 7sqc:1C 1700 60 0.0541 0.0124 0.3500 5.4 7sqc:1D
121 9fp6:A 732 111 0.0696 0.0369 0.2432 6.0 9fp6:B, 9fp6:C, 9fp6:D, 9fp6:E, 9fp6:F
122 6jfk:A 428 26 0.0309 0.0280 0.4615 6.0 6jfm:A, 6jfm:B
123 8p2f:E 670 69 0.0619 0.0358 0.3478 7.1 8p2g:E, 8p2h:E
124 3zdu:A 297 85 0.0541 0.0707 0.2471 7.2
125 6lsr:1 247 34 0.0387 0.0607 0.4412 7.3
126 6lsr:1 247 23 0.0284 0.0445 0.4783 8.3
127 4ncl:B 435 126 0.0799 0.0713 0.2460 7.5 4ncl:A, 4ncn:A, 4ncn:B, 4tmt:A, 4tmt:B, 4tmv:B, 4tmv:A, 4tmw:A, 4tmw:B, 4tmx:A, 4tmx:B, 4tmz:B, 4tmz:A, 4tn1:B, 4tn1:A
128 8pv1:CH 627 72 0.0670 0.0415 0.3611 7.8 8i9r:CH, 8i9t:CH, 8i9v:CH, 8i9w:CH, 8i9x:CH, 8i9y:CH, 8i9z:CH, 8ia0:CH, 8pv2:CH, 8pv3:CH, 8pv4:CH, 8pv5:CH, 8pv6:CH, 8pv7:CH, 8pv8:CH, 8pvk:CH, 8pvl:CH
129 8pv1:CH 627 141 0.0954 0.0590 0.2624 8.0 8i9r:CH, 8i9t:CH, 8i9v:CH, 8i9w:CH, 8i9x:CH, 8i9y:CH, 8i9z:CH, 8ia0:CH, 8pv2:CH, 8pv3:CH, 8pv4:CH, 8pv5:CH, 8pv6:CH, 8pv7:CH, 8pv8:CH, 8pvk:CH, 8pvl:CH
130 7am2:BK 694 84 0.0619 0.0346 0.2857 8.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218