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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKPEDFRASTQRPFTGEEYLKSLQDGREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWNTDTGSGGYT
HKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGRTPDYKAAFGCALGANPGFYGQFEQNARNWYTRIQETGLYFNHAIVNP
PIDRHLPTDKVKDVYIKLEKETDAGIIVSGAKVVATNSALTHYNMIGFNPDFALMFVAPMDADGVKLISRASYEMVAGAT
GSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRWTMEGGFARMYPLQACVRLAVKLDFITALLKKSLECTG
TLEFRGVQADLGEVVAWRNTFWALSDSMCSEATPWVNGAYLPDHAALQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSSA
RDLNNPQIDQYLAKYVRGSNGMDHVQRIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQNSGNMDKMMAM
VDRCLSEYDQDGWTVPHLHNNDDINMLDKLLK

The query sequence (length=512) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6qyi:B 520 520 1.0000 0.9846 0.9846 0.0 6b1b:A, 6b1b:B, 6eb0:C, 6qyh:B, 6qyi:A
2 2yyj:A 476 457 0.2773 0.2983 0.3107 2.22e-67 2yyi:A, 2yyl:A, 2yym:A
3 7e8p:D 482 487 0.2285 0.2427 0.2402 1.01e-29 7e8p:A, 7e8p:B, 7e8p:C, 7e8q:A, 7e8q:B, 7e8q:C, 7e8q:D
4 6vjr:A 502 446 0.1934 0.1972 0.2220 8.74e-21 6vjr:C, 6vjr:B, 6vjr:D
5 1u8v:A 490 279 0.1328 0.1388 0.2437 1.53e-20 1u8v:B, 1u8v:C, 1u8v:D
6 3bfm:A 230 104 0.0625 0.1391 0.3077 0.090
7 8ja7:E 443 56 0.0312 0.0361 0.2857 0.11 8ja8:A, 8ja9:A, 8jaa:A, 8jab:A, 8jac:A, 8jad:A, 7wda:A, 7wda:B, 7wda:C, 7wda:D
8 7caf:E 443 66 0.0332 0.0384 0.2576 0.59 8hpl:E, 8hpm:E, 8hpn:E, 8hpr:E
9 2w58:A 188 114 0.0527 0.1436 0.2368 2.5
10 2yfn:A 719 49 0.0273 0.0195 0.2857 3.5 2yfo:A
11 7qfo:A 379 39 0.0234 0.0317 0.3077 4.2 7qfn:A, 7zbg:A
12 5hc9:A 425 92 0.0430 0.0518 0.2391 7.3 3h39:A, 3h39:B, 3h3a:A, 3h3a:B, 5hc9:B
13 8dfv:A 1664 87 0.0430 0.0132 0.2529 9.2
14 3fge:A 198 33 0.0273 0.0707 0.4242 9.3
15 7mw1:B 621 32 0.0254 0.0209 0.4062 9.3 7mw1:A, 7tbj:D1, 7tbj:D2, 7tbj:D3, 7tbj:D4, 7tbj:D5, 7tbj:D6, 7tbj:D7, 7tbk:D1, 7tbk:D2, 7tbk:D3, 7tbk:D4, 7tbk:D5, 7tbk:D6, 7tbk:D7, 7tbl:D1, 7tbl:D2, 7tbl:D3, 7tbl:D4, 7tbl:D5, 7tbl:D6, 7tbl:D7, 7tbm:D1, 7tbm:D2, 7tbm:D3, 7tbm:D4, 7tbm:D5, 7tbm:D6, 7tbm:D7
16 7ape:A 435 57 0.0293 0.0345 0.2632 9.5 7ape:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218