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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKMPAYEFWFVVGSQHLYGDEALAQVEAHAREMVPALQAAVGNAHVLRWKGVLKDADEIRRLCLEASADDVCAGVIAWMH
TFSPAKMWIRGLLALRKPLLHLHTQFNRDIPWDTIDMDFMNLNQSAHGDREYGFIGARMGVARKVVVGHWEDPEVRERLA
KWMRTAVAFAESRNLKVARFGDNMREVAVTEGDKVGAQIQFGWSVNGYGIGDLVQYIRDVSEQKVNELLDEYEELYDIVP
AGRQEGPVRESIREQARIELGLKAFLQDGNFTAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVM
STGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLVFDGGEGAAVNASLIDLGH
RFRLIVNEVDAVKPEHDMPKLPVARILWKPRPSLRDSAEAWILAGGAHHTCFSFAVTTEQLQDFAEMAGIECVVINEHTS
VSSFKNELKWNEVFWR

The query sequence (length=496) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7chl:A 498 496 1.0000 0.9960 1.0000 0.0 7chl:B, 7chl:C, 7chl:D, 7chl:E, 7chl:F, 7chl:G, 7chl:H, 7chl:I, 7chl:J, 7chl:K, 7chl:L, 7cxo:A, 7cxo:B, 7cxo:C, 7cxo:D, 7cxo:E, 7cxo:F
2 4r1q:E 496 496 0.8629 0.8629 0.8629 0.0 4r1p:A, 4r1p:B, 4r1p:C, 4r1p:D, 4r1p:E, 4r1p:F, 4r1q:A, 4r1q:D, 4r1q:B, 4r1q:F, 4r1q:C
3 7cyy:C 497 496 0.7440 0.7425 0.7440 0.0 7cx7:A, 7cx7:B, 7cx7:C, 7cx7:D, 7cx7:E, 7cx7:F, 7cyy:A, 7cyy:B, 7cyy:D, 7cyy:E, 7cyy:F
4 4f2d:A 498 490 0.6472 0.6446 0.6551 0.0 4f2d:B, 4f2d:C, 2hxg:A, 2hxg:B, 2hxg:C
5 7ch3:B 495 495 0.6048 0.6061 0.6061 0.0 7ch3:C, 7ch3:D, 7ch3:E, 7ch3:I, 7ch3:F, 7ch3:G, 7ch3:H, 7ch3:J, 7ch3:K, 7ch3:L, 7cwv:A, 7cwv:B, 7cwv:C, 7cwv:D, 7cwv:E, 7cwv:F, 7cwv:G, 7cwv:H, 7cwv:I, 7cwv:J, 7cwv:K, 7cwv:L
6 7ch3:A 469 495 0.5806 0.6141 0.5818 0.0
7 3las:A 166 99 0.0524 0.1566 0.2626 0.79 3las:B
8 2hwg:A 572 129 0.0625 0.0542 0.2403 1.5 2hwg:B, 6v9k:A, 6v9k:B
9 4ppr:A 300 56 0.0343 0.0567 0.3036 4.4
10 6z1h:A 382 81 0.0444 0.0576 0.2716 4.6
11 5yj7:C 490 48 0.0282 0.0286 0.2917 4.9
12 6z1m:A 423 81 0.0444 0.0520 0.2716 5.8 6z1m:B, 6z1m:C
13 8t9g:C 536 41 0.0282 0.0261 0.3415 7.1 8fyh:A, 8fyh:G
14 8tas:E 570 41 0.0282 0.0246 0.3415 7.7 8tb9:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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