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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKMLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFFIVDLLVQYSPNKREGFLSPLKAYLISEEFF
NLLAQKLELHKFIRIKRGKINETIIGDVFEALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGRVKKDYKTILQEIT
QKRWKERPEYRLISVEGPHHKKKFIVEAKIKEYRTLGEGKSKKEAEQRAAEELIKLLEESE

The query sequence (length=221) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1yyk:A 221 221 1.0000 1.0000 1.0000 3.14e-159 2ez6:A, 2ez6:B, 1jfz:A, 1jfz:B, 1jfz:C, 1jfz:D, 4m2z:A, 4m2z:B, 4m30:A, 4m30:B, 2nue:A, 2nuf:A, 2nuf:B, 2nug:A, 2nug:B, 1rc5:A, 1rc5:B, 1rc5:C, 1rc5:D, 1rc7:A, 1yyo:A, 1yyw:A, 1yyw:C, 1yz9:A
2 7r97:A 226 224 0.3439 0.3363 0.3393 9.52e-28 7r97:B
3 7v6c:A 1540 252 0.3303 0.0474 0.2897 2.32e-19
4 7w0b:A 1586 253 0.3213 0.0448 0.2806 5.88e-18 7w0d:F
5 8hf0:A 1561 259 0.3213 0.0455 0.2741 2.90e-17 8hf0:D, 8hf1:A, 8hf1:D, 8hf1:G, 7w0a:A, 7w0a:E, 7w0c:A, 7w0d:A, 7w0e:A, 7w0f:A
6 7xw2:A 725 157 0.2127 0.0648 0.2994 5.62e-17
7 7xw2:A 725 62 0.0860 0.0262 0.3065 3.7
8 5zal:A 1314 158 0.2127 0.0358 0.2975 8.56e-17 2eb1:A, 2eb1:B, 2eb1:C, 4ngd:A, 5zam:A
9 5zal:A 1314 134 0.1629 0.0274 0.2687 0.055 2eb1:A, 2eb1:B, 2eb1:C, 4ngd:A, 5zam:A
10 7yym:A 1281 154 0.2081 0.0359 0.2987 1.06e-16 4ngb:A, 4ngc:A, 4ngg:A, 4nh3:A, 4nh5:A, 4nh6:A, 7yyn:A, 7zpi:A, 7zpj:A, 7zpk:A
11 7yym:A 1281 73 0.0950 0.0164 0.2877 1.5 4ngb:A, 4ngc:A, 4ngg:A, 4nh3:A, 4nh5:A, 4nh6:A, 7yyn:A, 7zpi:A, 7zpj:A, 7zpk:A
12 8dg5:A 1635 164 0.2081 0.0281 0.2805 8.01e-16 8dg7:A
13 8dg5:A 1635 100 0.1222 0.0165 0.2700 0.99 8dg7:A
14 8dfv:A 1664 164 0.2081 0.0276 0.2805 8.91e-16
15 8dfv:A 1664 100 0.1222 0.0162 0.2700 1.0
16 7eld:A 1137 142 0.2036 0.0396 0.3169 4.90e-14 7ele:A
17 7eld:A 1137 124 0.1629 0.0317 0.2903 7.38e-06 7ele:A
18 8dga:A 1629 176 0.2081 0.0282 0.2614 5.31e-14
19 8dga:A 1629 100 0.1222 0.0166 0.2700 1.3
20 5b16:A 722 170 0.2262 0.0693 0.2941 1.04e-12
21 5b16:A 722 235 0.2624 0.0803 0.2468 2.13e-12
22 2a11:A 154 146 0.2127 0.3052 0.3219 1.70e-12
23 6lxe:A 768 162 0.2217 0.0638 0.3025 3.99e-12
24 6lxe:A 768 155 0.1719 0.0495 0.2452 1.81e-06
25 6lxd:A 918 235 0.2624 0.0632 0.2468 2.09e-11 9asm:A, 9asn:A, 9aso:A, 9asp:A, 9asq:A, 6v5b:A, 6v5c:A
26 6lxd:A 918 114 0.1629 0.0392 0.3158 1.71e-07 9asm:A, 9asn:A, 9aso:A, 9asp:A, 9asq:A, 6v5b:A, 6v5c:A
27 7vg3:A 860 155 0.1946 0.0500 0.2774 1.31e-09 7vg2:A
28 7vg3:A 860 83 0.1131 0.0291 0.3012 0.097 7vg2:A
29 7zpk:C 233 79 0.1176 0.1116 0.3291 3.88e-06 3adl:A, 5n8l:A, 5n8m:A
30 7zpk:C 233 64 0.0995 0.0944 0.3438 10.0 3adl:A, 5n8l:A, 5n8m:A
31 1di2:A 69 60 0.1041 0.3333 0.3833 6.81e-06
32 8dfv:K 253 101 0.1448 0.1265 0.3168 7.17e-05 8dg5:K
33 8dfv:K 253 65 0.1086 0.0949 0.3692 0.001 8dg5:K
34 8dga:K 182 65 0.1086 0.1319 0.3692 3.14e-04 8dg7:K
35 6sdw:A 177 62 0.0860 0.1073 0.3065 3.60e-04 6htu:A, 6htu:B, 6htu:C, 6sdy:A
36 6sdw:A 177 43 0.0860 0.1073 0.4419 0.032 6htu:A, 6htu:B, 6htu:C, 6sdy:A
37 3rv0:B 304 212 0.2760 0.2007 0.2877 5.00e-04 3rv0:A, 3rv0:C, 3rv0:D
38 1ekz:A 76 45 0.0769 0.2237 0.3778 5.69e-04
39 5t16:A 276 100 0.1267 0.1014 0.2800 0.004 2lbs:B, 2lup:B, 4oog:C, 5t16:B, 5t16:I, 5t16:J, 1t4l:B
40 2ffl:A 732 117 0.1584 0.0478 0.2991 0.018 2ffl:B, 2ffl:C, 2ffl:D, 2qvw:A, 2qvw:B, 2qvw:C, 2qvw:D
41 7zlq:B 82 50 0.0724 0.1951 0.3200 0.031 7zlq:A
42 5ztm:A 168 69 0.0905 0.1190 0.2899 0.14 5ztm:B
43 7v6c:B 260 84 0.0905 0.0769 0.2381 0.14
44 7v6c:B 260 62 0.0724 0.0615 0.2581 0.33
45 2l3j:A 236 47 0.0679 0.0636 0.3191 0.15 2l3c:A
46 2l3j:A 236 53 0.0724 0.0678 0.3019 3.2 2l3c:A
47 1di2:B 60 60 0.0860 0.3167 0.3167 2.1
48 4at5:A 294 50 0.0543 0.0408 0.2400 2.3 4at3:A, 4at4:A
49 4gd3:A 179 64 0.0679 0.0838 0.2344 2.6 6g94:A, 6g94:B, 4gd3:B
50 7nkb:G 251 78 0.0905 0.0797 0.2564 3.3 7nkk:G, 7nkn:G
51 5dv7:C 137 51 0.0724 0.1168 0.3137 3.7
52 5dv7:C 137 52 0.0724 0.1168 0.3077 6.9
53 9asp:C 92 64 0.0905 0.2174 0.3125 6.6
54 5mza:A 440 54 0.0769 0.0386 0.3148 6.7
55 6ywe:5 350 56 0.0769 0.0486 0.3036 7.7 6yws:5, 6ywv:5, 6ywx:5, 6ywy:5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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