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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVKMTLKNREPVQLETLSIRGNNIRYFILPDSLPLDTLL

The query sequence (length=80) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7abg:g 93 79 0.9750 0.8387 0.9873 1.22e-50 7a5p:n, 7abg:n, 7abi:n, 7abi:g, 6ah0:V, 6ahd:b, 7b0y:k, 8c6j:l, 8c6j:c, 8ch6:k, 8ch6:5, 7dvq:c, 7dvq:j, 9fmd:c, 9fmd:j, 8h6e:5b, 8h6e:4b, 8h6j:5b, 8h6j:4b, 8h6k:5b, 8h6l:5b, 8i0p:b, 8i0p:n, 8i0r:b, 8i0r:n, 8i0s:b, 8i0s:n, 8i0t:b, 8i0t:n, 8i0u:b, 8i0u:n, 8i0v:b, 8i0v:n, 8i0w:b, 8i0w:j, 6icz:j, 6id0:j, 6id1:j, 5mqf:g, 5o9z:n, 5o9z:g, 4pjo:C, 4pjo:c, 4pjo:Q, 4pjo:q, 8q7q:a, 8q7v:a, 8q7w:a, 8q7x:a, 8q91:i, 6qdv:l, 6qdv:h, 8qo9:21, 8qo9:51, 8qo9:41, 7qtt:k, 6qw6:41, 6qw6:51, 6qx9:11, 6qx9:51, 6qx9:21, 6qx9:41, 8qxd:21, 8qxd:41, 8qxd:51, 8qzs:51, 8qzs:21, 8r08:11, 8r08:41, 8r08:21, 8r08:51, 8r09:21, 8r09:51, 8r09:41, 8r0a:51, 8r0a:21, 8r0a:41, 8r0b:21, 8r0b:41, 8r0b:51, 8rc0:i, 8rm5:21, 8rm5:51, 8rm5:41, 8ro2:c, 7vpx:h, 7w59:c, 7w59:j, 7w5a:c, 7w5a:j, 7w5b:c, 7w5b:j, 4wzj:C, 4wzj:J, 4wzj:Q, 4wzj:CC, 4wzj:JJ, 4wzj:QQ, 4wzj:CCC, 4wzj:JJJ, 4wzj:QQQ, 4wzj:CCCC, 4wzj:JJJJ, 4wzj:QQQQ, 5xjc:c, 5xjc:j, 8y6o:b, 8y6o:i, 8y6o:p, 8y7e:j, 5yzg:c, 5yzg:j, 5z56:c, 5z56:j, 5z57:c, 5z57:j, 5z58:c, 5z58:j
2 3jb9:F 82 80 0.8500 0.8293 0.8500 5.97e-45 3jb9:f
3 8ro0:c 80 79 0.8250 0.8250 0.8354 1.06e-43 8ro1:c
4 5nrl:l 99 80 0.5875 0.4747 0.5875 7.45e-22 6bk8:h, 7dco:m, 6exn:h, 6g90:t, 5gam:h, 5gan:l, 5gan:h, 5gao:l, 5gm6:m, 5gmk:m, 5gmk:z, 5lj3:h, 5lj3:l, 5lj5:h, 5lj5:l, 5mps:h, 5mq0:h, 5nrl:t, 5nrl:h, 7oqb:t, 7oqe:t, 5wsg:m, 5wsg:V, 5y88:f, 5y88:m, 5ylz:f, 5ylz:m, 5zwm:Q, 5zwm:m, 5zwo:Q, 5zwo:m
5 6g90:h 107 95 0.5750 0.4299 0.4842 2.14e-19 6exn:l, 7oqc:h, 7oqe:h
6 6j6g:m 119 107 0.5875 0.3950 0.4393 1.29e-17 7b9v:l, 7b9v:h, 6j6g:z, 6j6h:m, 6j6h:z, 6j6n:m, 6j6n:z, 6j6q:m, 6j6q:z, 6n7p:L, 6n7r:L, 6n7x:L, 8w2o:L, 5zwn:b
7 3jb9:D 96 73 0.3125 0.2604 0.3425 2.00e-09 3jb9:Z
8 6v4x:C 114 74 0.3000 0.2105 0.3243 9.25e-08
9 8ro0:a 81 71 0.2875 0.2840 0.3239 2.28e-07 8ro1:a
10 8c6j:d 84 71 0.2750 0.2619 0.3099 2.43e-07 7a5p:l, 7a5p:a, 7abg:e, 7abg:l, 7abi:l, 6ah0:h, 6ah0:T, 6ahd:g, 6ahd:h, 7b0y:i, 8c6j:n, 8ch6:j, 8ch6:3, 7dvq:h, 7evo:e, 9fmd:h, 9fmd:a, 8h6e:5g, 8h6e:4g, 8h6e:2g, 8h6j:5g, 8h6j:4g, 8h6j:2g, 8h6k:5g, 8h6k:2g, 8h6l:5g, 8h6l:2g, 8hk1:e, 8i0p:g, 8i0p:l, 8i0r:g, 8i0r:l, 8i0s:g, 8i0s:l, 8i0t:g, 8i0t:l, 8i0u:g, 8i0u:l, 8i0v:g, 8i0v:l, 8i0w:g, 8i0w:h, 6id1:a, 5mqf:l, 5o9z:W, 5o9z:e, 4pjo:A, 4pjo:a, 4pjo:O, 4pjo:o, 8q7q:d, 8q7v:d, 8q7w:d, 8q7x:d, 6qdv:n, 6qdv:d, 8qo9:23, 8qo9:53, 8qo9:43, 7qtt:j, 6qw6:43, 6qw6:53, 6qx9:13, 6qx9:53, 6qx9:23, 6qx9:43, 8qxd:23, 8qxd:43, 8qzs:53, 8qzs:23, 8qzs:43, 8r08:13, 8r08:23, 8r08:43, 8r09:23, 8r09:53, 8r09:43, 8r0a:53, 8r0a:23, 8r0a:43, 8r0b:23, 8r0b:43, 8r0b:53, 8rm5:23, 8rm5:43, 8ro2:a, 6v4x:A, 7vpx:e, 7vpx:j, 7w59:a, 7w59:h, 7w5a:a, 7w5a:h, 7w5b:a, 7w5b:h, 4wzj:A, 4wzj:H, 4wzj:O, 4wzj:AA, 4wzj:HH, 4wzj:OO, 4wzj:AAA, 4wzj:HHH, 4wzj:OOO, 4wzj:AAAA, 4wzj:HHHH, 4wzj:OOOO, 5xjc:a, 5xjc:h, 6y53:l, 6y5q:l, 8y6o:d, 8y6o:k, 8y6o:r, 8y7e:h, 5yzg:a, 5yzg:h, 5z56:a, 5z56:h, 5z57:a, 5z57:h, 5z58:a, 5z58:h
11 6qw6:62 95 73 0.2875 0.2421 0.3151 1.42e-05 6ahd:q, 8h6e:6a, 8h6j:6a, 8h6k:6a, 8h6l:6a, 6qx9:62
12 5vsu:B 98 72 0.2750 0.2245 0.3056 2.97e-05 6aso:B, 5gan:2, 4m7a:I, 4m7a:B, 4m7d:I, 4m7d:B, 5nrl:a
13 6qw6:64 73 57 0.2375 0.2603 0.3333 4.69e-05 6qx9:64
14 6ppn:D 88 61 0.2625 0.2386 0.3443 5.61e-05 6ppn:L, 6ppp:D, 6ppp:L, 6ppq:D, 6ppv:D
15 6ppn:B 94 82 0.3125 0.2660 0.3049 5.91e-05 6ppn:J, 6ppp:B, 6ppp:J, 6ppq:B, 6ppv:B
16 6g90:d 93 71 0.2375 0.2043 0.2676 2.21e-04 7b9v:n, 7b9v:d, 6bk8:o, 6bk8:g, 7dco:l, 6exn:n, 6exn:d, 6g90:v, 5gam:d, 5gan:n, 5gan:d, 5gao:n, 5gm6:l, 5gmk:l, 5gmk:y, 6j6g:l, 6j6g:y, 6j6h:l, 6j6h:y, 6j6n:l, 6j6n:y, 6j6q:l, 6j6q:y, 3jcm:J, 3jcm:R, 5lj3:d, 5lj3:n, 5lj5:d, 5lj5:n, 5mps:d, 5mq0:n, 5mq0:d, 6n7p:N, 6n7r:N, 6n7x:N, 5nrl:v, 5nrl:n, 5nrl:d, 7oqb:v, 7oqc:d, 7oqe:d, 7oqe:v, 8w2o:N, 5wsg:l, 5wsg:U, 5y88:e, 5y88:l, 5ylz:e, 5ylz:l, 5zwm:S, 5zwm:d, 5zwm:l, 5zwn:d, 5zwo:d, 5zwo:S
17 5gan:4 74 62 0.2750 0.2973 0.3548 3.39e-04 4m7a:N, 4m7a:G, 4m7d:N, 5nrl:j, 5vsu:D
18 5mkn:d 72 57 0.2375 0.2639 0.3333 0.001 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
19 6aso:D 59 61 0.2625 0.3559 0.3443 0.008
20 6tfl:A 62 54 0.2250 0.2903 0.3333 0.009 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
21 3jb9:I 73 62 0.2375 0.2603 0.3065 0.020 3jb9:n
22 3jb9:J 73 59 0.2000 0.2192 0.2712 0.021 3jb9:o
23 6ppq:F 71 62 0.2250 0.2535 0.2903 0.041 6ppn:F, 6ppn:N, 6ppp:F, 6ppp:N, 6ppv:F
24 6qw6:66 72 62 0.2000 0.2222 0.2581 0.076 6qx9:66
25 5a31:A 1441 46 0.2250 0.0125 0.3913 0.14 5g04:A, 4ui9:A
26 6tnt:A 1583 46 0.2250 0.0114 0.3913 0.14 5g05:A, 6tm5:A
27 7qe7:A 1648 46 0.2250 0.0109 0.3913 0.16
28 1i5l:C 74 58 0.2375 0.2568 0.3276 0.26 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
29 2v95:A 342 29 0.1500 0.0351 0.4138 0.29
30 1m8v:A 72 53 0.1750 0.1944 0.2642 0.37 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
31 4wj3:B 456 30 0.1750 0.0307 0.4667 0.57 4wj3:K, 4wj3:H, 4wj3:E
32 1loj:C 77 53 0.2125 0.2208 0.3208 0.89 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
33 7b9v:q 75 63 0.2375 0.2533 0.3016 0.95 7b9v:f, 6bk8:b, 7dco:j, 6exn:q, 6exn:f, 6g90:f, 6g90:x, 5gam:f, 5gan:q, 5gan:f, 5gao:q, 5gm6:h, 5gmk:h, 5gmk:w, 6j6g:h, 6j6g:w, 6j6h:h, 6j6h:w, 6j6n:h, 6j6n:w, 6j6q:h, 6j6q:w, 5lj3:f, 5lj5:f, 5mps:f, 5mq0:f, 6n7p:P, 6n7r:P, 6n7x:P, 5nrl:x, 5nrl:q, 5nrl:f, 7oqc:f, 8w2o:P, 5wsg:h, 5wsg:H, 5y88:c, 5y88:j, 5ylz:c, 5ylz:j, 5zwm:U, 5zwm:j, 5zwn:f, 5zwo:U, 5zwo:j
34 4c49:A 367 29 0.1375 0.0300 0.3793 1.2 4bb2:A, 4bb2:B, 4c49:B, 4c49:C, 4c49:D, 2vdy:A, 2vdy:B
35 2qkm:B 266 27 0.1375 0.0414 0.4074 1.3 5j3t:B, 5kq4:E, 5kq4:B, 5n2v:B, 5n2v:E, 2qkm:F
36 6jp4:A 770 56 0.1750 0.0182 0.2500 2.0 6jp4:B, 6jp4:C, 6jph:A, 6jpn:A
37 7mfm:G 1483 21 0.1250 0.0067 0.4762 2.2 7mfm:H, 7mft:G
38 9bht:E 288 45 0.2125 0.0590 0.3778 3.1 9bht:B
39 7b9v:p 77 65 0.2125 0.2208 0.2615 6.4 7b9v:e, 6bk8:c, 7dco:i, 6exn:p, 6exn:e, 6g90:e, 6g90:w, 5gan:p, 5gao:p, 5gm6:i, 5gmk:i, 5gmk:u, 6j6g:i, 6j6g:u, 6j6h:i, 6j6h:u, 6j6n:i, 6j6n:u, 6j6q:i, 6j6q:u, 5mps:e, 5mq0:e, 6n7p:O, 6n7r:O, 6n7x:O, 5nrl:w, 5nrl:p, 5nrl:e, 7oqb:w, 7oqc:e, 7oqe:w, 8w2o:O, 5wsg:i, 5wsg:G, 5y88:b, 5y88:i, 5ylz:b, 5ylz:i, 5zwm:T, 5zwm:i, 5zwn:e, 5zwo:T, 5zwo:i
40 7dd9:A 1129 43 0.1875 0.0133 0.3488 6.5 7dd9:C, 7dd9:E, 7dd9:G, 6lz1:A, 6lz1:B, 6lz1:C, 6lz1:D
41 5u34:A 960 25 0.1500 0.0125 0.4800 7.0
42 5wqe:A 1011 25 0.1500 0.0119 0.4800 7.0
43 5u30:A 1085 25 0.1500 0.0111 0.4800 7.0 5u31:A, 5u33:A
44 6z1p:BA 138 35 0.1375 0.0797 0.3143 8.2
45 5tqm:A 315 29 0.1500 0.0381 0.4138 8.7 5tqm:B
46 5eg1:B 576 40 0.2000 0.0278 0.4000 9.7 5eg1:A, 5ofr:A, 5ofr:B, 4pl0:A, 4pl0:B, 8px9:A, 8px9:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218