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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKLTLWTYEGPPHVGAMRVATAMKDLQLVLHGPQGDTYADLLFTMIERRNARPPVSFSTFEASHMGTDTAILLKDALAAA
HARYKPQAMAVALTCTAELLQDDPNGISRALNLPVPVVPLELPSYSRKENYGADETFRALVRALAVPMERTPEVTCNLLG
ATALGFRHRDDVAEVTKLLATMGIKVNVCAPLGASPDDLRKLGQAHFNVLMYPETGESAARHLERACKQPFTKIVPIGVG
ATRDFLAEVSKITGLPVVTDESTLRQPWWSASVDSTYLTGKRVFIFGDGTHVIAAARIAAKEVGFEVVGMGCYNREMARP
LRTAAAEYGLEALITDDYLEVEKAIEAAAPELILGTQMERNIAKKLGLPCAVISAPVHVQDFPARYAPQMGFEGANVLFD
TWVHPLVMGLEEHLLTMFR

The query sequence (length=419) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3aer:D 421 419 1.0000 0.9952 1.0000 0.0 3aek:B, 3aek:D, 3aeq:B, 3aeq:D, 3aer:B, 3aes:B, 3aes:D, 3aet:B, 3aet:D, 3aeu:D
2 2ynm:D 488 426 0.6420 0.5512 0.6315 0.0
3 2afh:B 522 450 0.2601 0.2088 0.2422 1.70e-20 2afh:D, 2afi:B, 2afi:D, 2afi:J, 2afi:L, 6bbl:B, 6bbl:D, 8bts:B, 8bts:D, 8bts:I, 8bts:L, 5bvg:B, 5bvg:D, 5bvh:B, 5bvh:D, 6cdk:B, 6cdk:D, 8crs:D, 8crs:B, 5cx1:B, 5cx1:D, 5cx1:F, 5cx1:H, 5cx1:J, 5cx1:L, 5cx1:N, 5cx1:P, 8dbx:B, 8dbx:D, 8dby:B, 8dby:D, 8dfc:B, 8dfc:D, 8dfd:B, 8dfd:D, 8dpn:B, 8dpn:D, 8e3t:B, 8e3t:D, 8e3u:B, 8e3u:D, 8e3v:B, 8e3v:D, 8enl:B, 8enl:D, 8enm:B, 8enm:D, 8enn:B, 8enn:D, 8eno:B, 8eno:D, 1fp4:B, 1fp4:D, 1g20:B, 1g20:D, 1g21:B, 1g21:D, 7jrf:B, 7jrf:D, 3k1a:B, 3k1a:D, 1l5h:B, 1m1n:B, 1m1n:D, 1m1n:F, 1m1n:H, 1m1y:B, 1m1y:D, 1m1y:J, 1m1y:L, 1m34:B, 1m34:D, 1m34:J, 1m34:L, 7mci:B, 7mci:D, 2min:B, 2min:D, 3min:B, 3min:D, 1n2c:B, 1n2c:D, 4nd8:B, 4nd8:D, 6o7l:B, 6o7l:D, 6o7m:B, 6o7m:D, 6o7n:B, 6o7n:D, 6o7o:B, 6o7o:D, 6o7p:B, 6o7p:D, 6o7q:B, 6o7q:D, 6o7r:B, 6o7r:D, 6o7s:B, 6o7s:D, 6op1:B, 6op1:D, 6op2:B, 6op2:D, 6op3:B, 6op3:D, 6op4:B, 6op4:D, 8p8g:B, 8p8g:D, 4tku:B, 4tku:D, 4tkv:B, 4tkv:D, 3u7q:B, 3u7q:D, 6ug0:B, 6ug0:D, 7ut6:B, 7ut6:D, 7ut7:B, 7ut7:D, 7ut8:B, 7ut8:D, 7ut9:B, 7ut9:D, 7uta:B, 7uta:D, 5vq4:B, 5vq4:D, 6vxt:B, 6vxt:D, 4wna:B, 4wna:D, 4wza:B, 4wza:D, 4wzb:B, 4wzb:D, 4xpi:B, 4xpi:D
4 5vpw:B 458 431 0.2625 0.2402 0.2552 1.75e-18 1mio:B, 1mio:D, 5vpw:D, 5vq3:B, 5vq3:D, 4wes:B, 4wes:D, 4wn9:B, 4wn9:D
5 8boq:B 461 441 0.2745 0.2495 0.2608 3.21e-18 8boq:E
6 8boq:A 515 405 0.2315 0.1883 0.2395 3.76e-13 8boq:D
7 8oie:C 456 438 0.2506 0.2303 0.2397 7.99e-13 8oie:H, 8pbb:B, 8pbb:D
8 5koh:B 510 416 0.2053 0.1686 0.2067 9.33e-13 5koh:D, 5koj:B, 5koj:D
9 8oie:A 520 410 0.2339 0.1885 0.2390 4.34e-12 8oie:F
10 1h1l:B 519 441 0.2124 0.1715 0.2018 3.02e-09 1h1l:D, 1qgu:B, 1qgu:D, 1qh1:B, 1qh1:D, 1qh8:B, 1qh8:D
11 7adr:A 473 390 0.1957 0.1734 0.2103 7.93e-09 7adr:D, 7ady:A, 7ady:D, 7aiz:A, 7aiz:D, 6fea:A, 6fea:D, 5n6y:A, 5n6y:D
12 7adr:E 466 424 0.2220 0.1996 0.2193 2.83e-07 7adr:B, 7ady:B, 7ady:E, 7aiz:B, 7aiz:E, 6fea:B, 6fea:E, 5n6y:B, 5n6y:E
13 5vpw:C 495 254 0.1360 0.1152 0.2244 5.45e-06
14 1mio:A 525 254 0.1360 0.1086 0.2244 7.42e-06 1mio:C, 5vpw:A, 5vq3:A, 5vq3:C, 4wes:A, 4wes:C, 4wn9:A, 4wn9:C
15 4xpi:A 479 341 0.1862 0.1628 0.2287 3.11e-05 2afh:A, 2afh:C, 2afi:A, 2afi:C, 2afi:I, 2afi:K, 6bbl:A, 6bbl:C, 8bts:A, 8bts:C, 8bts:H, 8bts:J, 5bvg:A, 5bvg:C, 5bvh:A, 5bvh:C, 6cdk:A, 6cdk:C, 8crs:A, 8crs:C, 5cx1:A, 5cx1:C, 5cx1:E, 5cx1:G, 5cx1:I, 5cx1:K, 5cx1:M, 5cx1:O, 8dbx:A, 8dbx:C, 8dby:A, 8dby:C, 8dfc:A, 8dfc:C, 8dfd:A, 8dfd:C, 8dpn:A, 8dpn:C, 8e3t:A, 8e3t:C, 8e3u:A, 8e3u:C, 8e3v:A, 8e3v:C, 8enl:A, 8enm:A, 8enm:C, 8enn:A, 8enn:C, 8eno:A, 1fp4:A, 1fp4:C, 1g20:A, 1g20:C, 1g21:A, 1g21:C, 7jrf:A, 7jrf:C, 3k1a:A, 3k1a:C, 1m1n:A, 1m1n:C, 1m1n:E, 1m1n:G, 1m1y:A, 1m1y:C, 1m1y:I, 1m1y:K, 1m34:A, 1m34:C, 1m34:I, 1m34:K, 7mci:A, 7mci:C, 2min:A, 2min:C, 3min:A, 3min:C, 1n2c:A, 1n2c:C, 4nd8:A, 4nd8:C, 6o7l:A, 6o7l:C, 6o7m:A, 6o7m:C, 6o7n:A, 6o7n:C, 6o7o:A, 6o7o:C, 6o7p:A, 6o7p:C, 6o7q:A, 6o7q:C, 6o7r:A, 6o7r:C, 6o7s:A, 6o7s:C, 6op1:A, 6op1:C, 6op2:A, 6op2:C, 6op3:A, 6op3:C, 6op4:A, 6op4:C, 8p8g:A, 8p8g:C, 4tku:A, 4tku:C, 4tkv:A, 4tkv:C, 3u7q:A, 3u7q:C, 6ug0:A, 6ug0:C, 7ut6:A, 7ut6:C, 7ut7:A, 7ut7:C, 7ut8:A, 7ut8:C, 7ut9:A, 7ut9:C, 7uta:A, 7uta:C, 5vq4:A, 5vq4:C, 6vxt:A, 6vxt:C, 4wna:A, 4wna:C, 4wza:A, 4wza:C, 4wzb:A, 4wzb:C, 4xpi:C
16 5koh:A 483 359 0.1981 0.1718 0.2312 4.55e-05 5koh:C, 5koj:A, 5koj:C
17 3pdi:A 427 264 0.1432 0.1405 0.2273 2.19e-04 3pdi:C, 3pdi:E, 3pdi:G
18 2xdq:A 425 282 0.1480 0.1459 0.2199 8.34e-04
19 1h1l:A 478 330 0.1647 0.1444 0.2091 0.013 1h1l:C, 1qgu:A, 1qgu:C, 1qh1:A, 1qh1:C, 1qh8:A, 1qh8:C
20 3pdi:B 432 385 0.2148 0.2083 0.2338 0.27 3pdi:D, 3pdi:F, 3pdi:H
21 6f2a:C 326 84 0.0453 0.0583 0.2262 0.52 6f2a:A, 6f2a:B, 6f2a:D, 6f2b:A, 6f2b:B, 6f2b:C, 6f2b:D, 6f6j:A, 6f6j:B, 6f6j:C, 6f6j:D
22 8eno:C 407 338 0.1695 0.1744 0.2101 0.86 1l5h:A
23 1qxw:A 249 61 0.0501 0.0843 0.3443 2.2 1qxy:A, 1qxz:A
24 7bjv:D 240 73 0.0453 0.0792 0.2603 2.3 7bju:D, 7bjv:E, 7bjv:F, 3ixp:D, 1r1k:D, 1r20:D, 2r40:D, 4umm:G
25 1qo8:A 564 56 0.0430 0.0319 0.3214 2.6 1qo8:D
26 4gwi:A 144 94 0.0597 0.1736 0.2660 2.8 4gwj:A, 3le0:A, 3leg:A, 3lei:A, 3lek:A
27 7tr1:K 346 93 0.0549 0.0665 0.2473 5.0 7lff:A, 7lff:B
28 7tr3:K 418 93 0.0573 0.0574 0.2581 5.1 7tqx:K, 7tqy:K, 7tr0:K
29 8v2y:B 151 87 0.0644 0.1788 0.3103 5.6
30 6c66:A 511 104 0.0477 0.0391 0.1923 6.3 5u07:C, 5u0a:C
31 3efv:A 459 46 0.0382 0.0349 0.3478 6.3 3efv:B, 3efv:C, 3efv:D
32 8h9t:D 442 87 0.0597 0.0566 0.2874 6.7 8h9p:D
33 6i1d:A 458 85 0.0644 0.0590 0.3176 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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