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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETKWEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFR
VLKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVG
GGVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISVVKALMGILNINHPDIEEFIDAKKVLNFFNLSVGFPMDKKE
ILKLYEEDGELELSHPRSTIRKKVKIRELFRKIATNAWKSGDPGLAFLGEMNKYYPLYPHRKINSTNPCGEIGLSDYEAC
NLGSIDVAKFYNNGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNSQEAR
DFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVPFAMGMSNYDDEIREVMKMTKEFRRNVALLTIAPTGS
ISNIADTSSGLEPNFLLAYTRFPLLYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDIDPMDHLL
MQDAFQRYVDNNISKTINMPQSATVDDVLNVYLEALRTNVRGITVYRDGSL

The query sequence (length=611) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1xje:A 627 627 1.0000 0.9745 0.9745 0.0 3o0n:B, 3o0o:A, 3o0o:B, 3o0q:A, 3o0q:B, 1xje:B, 1xjf:A, 1xjf:B, 1xjg:A, 1xjg:B, 1xjj:A, 1xjj:B, 1xjk:A, 1xjk:B, 1xjm:A, 1xjn:A, 1xjn:B, 1xjn:C, 1xjn:D
2 3o0n:A 607 611 0.9935 1.0000 0.9935 0.0 1xjm:B
3 5im3:A 874 562 0.2357 0.1648 0.2562 2.39e-51 5im3:B
4 6aui:A 745 565 0.2406 0.1973 0.2602 4.68e-40 6aui:B, 6aui:C, 6aui:D, 6aui:E, 6aui:F, 3hnc:A, 3hnc:B, 3hnd:A, 3hnd:B, 3hne:A, 3hne:B, 3hnf:A, 3hnf:B, 6l3r:A, 6l3r:E, 6lkm:A, 6lkm:B, 5tus:A, 5tus:B, 2wgh:B, 4x3v:A, 4x3v:B
5 3rsr:A 610 536 0.2357 0.2361 0.2687 1.81e-39
6 6l7l:A 644 551 0.2324 0.2205 0.2577 1.86e-36 6l7l:E, 2wgh:A
7 3s8c:A 666 552 0.2308 0.2117 0.2554 3.59e-36 2cvu:A, 2cvv:A, 2cvw:A, 2cvx:A, 2cvy:A, 2eud:A, 3k8t:A, 3s87:A, 3s8a:A, 3s8b:A, 3tb9:A, 3tba:A, 2zlf:A, 2zlg:A, 1zzd:A
8 7agj:A 731 549 0.2291 0.1915 0.2550 9.89e-34 7agj:B
9 2cvt:A 637 547 0.2242 0.2151 0.2505 7.30e-33
10 7b9q:A 868 443 0.1817 0.1279 0.2506 3.90e-31 7b9q:B
11 7b9q:A 868 172 0.0835 0.0588 0.2965 1.20e-09 7b9q:B
12 6mve:A 680 595 0.2390 0.2147 0.2454 4.71e-30 6cgl:A, 6cgl:B, 6cgn:A, 6mt9:A, 6mv9:A, 6mv9:B, 6mw3:D, 6mw3:C, 6myx:C, 6myx:D, 6myx:I, 6myx:J
13 1peu:A 692 658 0.2504 0.2211 0.2325 1.22e-26 2bq1:E, 2bq1:F, 1peo:A, 1peq:A
14 7b9p:A 899 268 0.1227 0.0834 0.2799 2.15e-24
15 7b9p:A 899 164 0.0818 0.0556 0.3049 1.27e-09
16 7b9p:A 899 53 0.0360 0.0245 0.4151 1.43e-05
17 8vhu:A 743 436 0.1653 0.1359 0.2317 1.48e-16 5cns:A, 5cns:B, 5cns:C, 5cns:D, 5cnt:A, 5cnt:B, 5cnt:C, 5cnt:D, 5cnu:A, 5cnu:B, 5cnu:C, 5cnu:D, 5cnv:A, 5cnv:B, 5cnv:C, 5cnv:D, 4erm:A, 4erm:B, 4erm:C, 4erm:D, 4erp:A, 4erp:B, 4erp:C, 4erp:D, 1r1r:A, 1r1r:B, 1r1r:C, 2r1r:A, 2r1r:B, 2r1r:C, 3r1r:A, 3r1r:B, 3r1r:C, 4r1r:A, 4r1r:B, 4r1r:C, 5r1r:A, 5r1r:B, 5r1r:C, 6r1r:A, 6r1r:B, 6r1r:C, 7r1r:A, 7r1r:B, 7r1r:C, 3uus:A, 3uus:B, 3uus:C, 3uus:D, 8vhn:A, 8vhn:B, 8vho:A, 8vho:B, 8vhp:A, 8vhp:B, 8vhp:C, 8vhp:D, 8vhp:E, 8vhp:F, 8vhp:G, 8vhp:H, 8vhq:A, 8vhq:B, 8vhq:C, 8vhq:D, 8vhr:A, 8vhr:B, 8vhr:C, 8vhr:D, 8vhu:B, 6w4x:A, 6w4x:B, 2x0x:A, 2x0x:B, 2x0x:C, 2xak:A, 2xak:B, 2xak:C, 2xap:A, 2xap:B, 2xap:C, 2xav:A, 2xav:B, 2xav:C, 2xaw:A, 2xaw:B, 2xaw:C, 2xax:A, 2xax:B, 2xax:C, 2xay:A, 2xay:B, 2xay:C, 2xaz:A, 2xaz:B, 2xaz:C, 2xo4:A, 2xo4:B, 2xo4:C, 2xo5:A, 2xo5:B, 2xo5:C
18 7mdi:A 734 541 0.1817 0.1512 0.2052 7.20e-11 7mdi:B, 7mdi:D, 7mdi:C
19 7urg:A 401 105 0.0524 0.0798 0.3048 3.27e-05 7urg:B
20 3c61:A 314 95 0.0491 0.0955 0.3158 0.26 3c61:B, 3c61:C, 3c61:D, 6dgs:A, 6dgs:B, 6dwg:A, 6dwg:B, 6ebs:A, 6ebs:B, 4ef8:A, 4ef8:B, 4ef9:A, 4ef9:B, 3gye:A, 3gye:B, 3gz3:A, 3gz3:B, 3mhu:A, 3mhu:B, 3mjy:A, 3mjy:B, 7mx6:AAA, 7mx6:BBB, 7myd:AAA, 7myd:BBB, 3tjx:A, 3tjx:B, 3tq0:A, 3tq0:B, 3tro:A, 3tro:B
21 6vz8:D 531 65 0.0295 0.0339 0.2769 1.3 6vz8:H, 6vz8:L, 6vz8:P
22 3mkv:A 414 108 0.0540 0.0797 0.3056 4.4 3mkv:B, 3mkv:C, 3mkv:D, 3mkv:E, 3mkv:F, 3mkv:G, 3mkv:H
23 5k2o:A 585 58 0.0278 0.0291 0.2931 4.6 3e9y:A, 3ea4:A, 8et4:A, 8et5:A, 5k3s:A, 5k6q:A, 5k6r:A, 5k6t:A, 7stq:A, 7tzz:A, 7u1d:A, 7u1u:A, 7u25:A, 6u9h:A, 6u9h:B, 6u9h:H, 6u9h:I, 6u9h:L, 6u9h:M, 6u9h:P, 6u9h:Q, 6vz8:E, 6vz8:I, 6vz8:M, 6vz8:Q, 5wj1:A, 1ybh:A, 1yhy:A, 1yhz:A, 1yi0:A, 1yi1:A, 1z8n:A
24 7zi4:C 447 95 0.0376 0.0515 0.2421 8.8 9c57:E, 9c57:C, 9c57:A, 9c62:C, 9c62:E, 9c62:A, 6hts:A, 6hts:C, 6hts:E, 5oaf:A, 5oaf:C, 5oaf:E, 8x15:M, 8x15:O, 8x15:Q, 8x19:M, 8x19:O, 8x19:Q, 8x1c:M, 8x1c:O, 8x1c:Q, 8xvg:A, 8xvg:C, 8xvg:E, 8xvt:A, 8xvt:C, 8xvt:E, 7zi4:A, 7zi4:E
25 4qfh:B 611 153 0.0606 0.0606 0.2418 9.9 4qfh:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218