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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEI
EKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEE
FDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID
NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLR
FCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQS
VIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPD
GIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHH
YGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKL
PRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHR

The query sequence (length=677) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ebt:B 677 677 1.0000 1.0000 1.0000 0.0 7ad8:B, 8ebu:B, 8ebx:B, 8eby:B, 6ro4:B
2 8byq:1 760 730 1.0000 0.8908 0.9274 0.0 8bvw:1, 8ebs:B, 8ebv:B, 8ebw:B, 7egb:7, 7egc:7, 7ena:7, 7enc:7, 8gxq:HA, 8gxs:HA, 7lbm:X, 6nmi:B, 7nvr:0, 7nvw:0, 7nvx:0, 7nvy:0, 7nvz:0, 7nw0:0, 6o9l:0, 6o9m:0, 5of4:B, 8wak:7, 8wal:7, 8wan:7, 8wao:7, 8wap:7, 8waq:7, 8war:7, 8was:7
3 8rev:A 709 683 0.5391 0.5148 0.5344 0.0
4 7k01:0 754 730 0.5391 0.4841 0.5000 0.0 8cen:0, 8ceo:0, 6gym:0, 7k04:0, 7m2u:0, 7ml0:0, 7ml1:0, 7ml2:0, 7ml3:0, 7ml4:0, 7o4i:0, 7o4j:0, 7o4k:0, 7o4l:0, 7o72:0, 7o73:0, 7o75:0, 5oqj:0, 5oqm:0, 7zs9:0, 7zsa:0, 7zsb:0
5 4a15:A 596 430 0.1462 0.1661 0.2302 3.88e-12 5h8w:A, 2vsf:A
6 3crv:A 551 467 0.1566 0.1924 0.2270 4.92e-11 5h8c:A
7 3crw:1 485 449 0.1551 0.2165 0.2339 4.65e-08
8 7tra:A 572 98 0.0443 0.0524 0.3061 0.011
9 6fwr:A 699 230 0.0783 0.0758 0.2304 0.039 6fws:A, 6fws:B
10 6fwr:A 699 111 0.0428 0.0415 0.2613 3.8 6fws:A, 6fws:B
11 4paw:A 197 65 0.0340 0.1168 0.3538 0.90 4paw:B
12 3i8v:A 335 204 0.0694 0.1403 0.2304 0.93 3i8v:B, 2qyk:A, 2qyk:B, 3tvx:A, 3tvx:B
13 3vkh:B 2908 39 0.0236 0.0055 0.4103 4.5
14 3vkg:A 2954 39 0.0236 0.0054 0.4103 4.7
15 3vkg:B 2853 39 0.0236 0.0056 0.4103 4.7
16 3vkh:A 3042 39 0.0236 0.0053 0.4103 5.0
17 7z8f:e 4579 43 0.0266 0.0039 0.4186 8.0 5owo:A, 8pr2:f, 8ptk:m, 8ptk:n, 7z8f:f, 7z8f:m, 7z8f:n, 7z8h:A
18 8ptk:f 4502 43 0.0266 0.0040 0.4186 8.3 8ptk:e
19 8pqw:A 2892 43 0.0266 0.0062 0.4186 8.4 8pqy:A, 8pqz:A, 8pqz:J
20 7z8g:A 3047 43 0.0266 0.0059 0.4186 8.5 8fdu:A, 7z8l:f
21 8dyu:A 2562 43 0.0266 0.0070 0.4186 8.5 8dyv:A
22 8fcy:A 2864 43 0.0266 0.0063 0.4186 8.6 8fd6:A, 8fdt:A
23 5nug:A 2920 43 0.0266 0.0062 0.4186 8.7 5nug:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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