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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKKIFMMVHELDVNKGGMTSSMFNRSKEFYDADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNK
HFKSNKLLYKHISERLKNTIEIEESKGISRYFDITTRTYIAYIRKSKSEKVIDFFKDNKRIERFSFIDNKVHMKETFNVD
NKVCYQVFYDEKGYPYISRNINANNGAVGKTYVLVNKKEFKNNLALCVYYLEKLIKDSKDSIMICDGPGSFPKMFNTNHK
NAQKYGVIHVNHHENFDDTGAFKKSEKYIIENANKINGVIVLTEAQRLDILNQFDVENIFTISNFVKIHNAPKHFQTEKI
VGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSVKDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTS
QYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYST
ESILEKWLNLFNS

The query sequence (length=493) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4wad:A 498 493 0.9980 0.9880 0.9980 0.0 4x6l:A, 4x6l:B, 4x6l:C, 4x7m:A, 4x7m:B, 4x7r:A, 4x7r:B
2 8p1x:AAA 492 492 0.5213 0.5224 0.5224 0.0 8p20:AAA, 8p20:BBB, 8p20:CCC, 8p20:DDD, 7qd7:AAA, 7qh9:AAA, 7qh9:BBB, 7qh9:CCC, 7qh9:DDD
3 7ec3:A 500 337 0.1765 0.1740 0.2582 4.24e-27 7ec3:C, 7ec6:A, 7ec7:A, 7ec7:B, 7vfl:A, 7vfl:C, 7vfm:A, 7vfm:C, 7vfn:A, 7vfo:A, 7vfo:B
4 5e9u:A 503 308 0.1684 0.1650 0.2695 9.06e-22 5e9u:E
5 4pqg:A 506 345 0.1988 0.1937 0.2841 5.03e-18 4pqg:B
6 3mbo:E 375 177 0.0953 0.1253 0.2655 4.44e-13 3mbo:A, 3mbo:C, 3mbo:H
7 5d00:A 361 255 0.1217 0.1662 0.2353 4.18e-11 5d00:B, 5d01:A, 5d01:B
8 5n80:A 358 115 0.0609 0.0838 0.2609 2.33e-08 6y6i:A
9 6n1x:A 377 205 0.1055 0.1379 0.2537 6.42e-08 6d9t:A
10 8dqd:A 370 182 0.0953 0.1270 0.2582 1.37e-07 8dvw:A, 8dvz:A
11 5zer:A 354 176 0.0852 0.1186 0.2386 5.97e-07 5zer:B, 5zes:A, 5zfk:A, 5zfk:B
12 8qoy:A 1036 133 0.0771 0.0367 0.2857 1.67e-06
13 4xsu:A 368 167 0.0832 0.1114 0.2455 1.21e-05 4xsp:A, 4xsr:B, 4xsr:A, 4xsu:B
14 2xa2:A 412 223 0.1075 0.1286 0.2377 1.43e-05 2xa2:B, 2xa9:A, 2xa9:B, 2xmp:A, 2xmp:B
15 2r66:A 456 92 0.0487 0.0526 0.2609 8.48e-05 2r68:A
16 6kih:A 400 136 0.0669 0.0825 0.2426 3.56e-04 6kih:C, 6kih:D, 6kih:E, 6kih:F, 6kih:H, 6kih:I, 6kih:K, 6kih:L, 6kih:B, 6kih:G, 6kih:J
17 7fga:B 344 88 0.0487 0.0698 0.2727 0.001 7fg9:A, 7fg9:B, 7fga:D, 7fga:A, 7fga:C
18 3k9t:A 422 122 0.0690 0.0806 0.2787 0.006
19 6eji:A 360 177 0.0852 0.1167 0.2373 0.008 6eji:B, 6ejj:A, 6ejj:B, 6ejk:A, 6ejk:B
20 3s27:H 797 77 0.0467 0.0289 0.2987 0.013 3s27:A, 3s27:B, 3s27:C, 3s27:D, 3s27:E, 3s27:F, 3s27:G, 3s28:A, 3s28:B, 3s28:C, 3s28:D, 3s28:E, 3s28:F, 3s28:G, 3s28:H, 3s29:A, 3s29:B, 3s29:C, 3s29:D, 3s29:E, 3s29:F, 3s29:G, 3s29:H
21 3oka:A 378 186 0.0791 0.1032 0.2097 0.016 3oka:B, 3okc:A, 3okp:A
22 4mz7:B 493 206 0.1075 0.1075 0.2573 0.83 7a5y:A, 7a5y:B, 7a5y:C, 7a5y:D, 7a5y:E, 7a5y:F, 7a5y:G, 7a5y:H, 5ao0:A, 5ao0:B, 5ao1:A, 5ao1:B, 5ao1:C, 5ao1:D, 5ao2:A, 5ao2:B, 5ao2:C, 5ao2:D, 5ao3:A, 5ao3:C, 5ao3:B, 5ao3:D, 5ao4:A, 5ao4:B, 4bzb:A, 4bzb:C, 4bzb:D, 4bzb:B, 4bzc:A, 4bzc:C, 4bzc:D, 4bzc:B, 6cm2:D, 6cm2:A, 6cm2:B, 6cm2:C, 8d94:A, 8d94:D, 8d94:B, 8d94:C, 8d9j:A, 8d9j:D, 8d9j:B, 8d9j:C, 6dw3:D, 6dw3:C, 6dw3:B, 6dw3:A, 6dw4:D, 6dw4:C, 6dw4:B, 6dw4:A, 6dw5:A, 6dw5:D, 6dw5:B, 6dw5:C, 6dw7:A, 6dw7:B, 6dw7:C, 6dw7:D, 6dwd:D, 6dwd:A, 6dwd:C, 6dwd:B, 6dwj:D, 6dwj:A, 6dwj:C, 6dwj:B, 6dwk:A, 6dwk:D, 6dwk:B, 6dwk:C, 8gb1:A, 8gb1:B, 8gb1:C, 8gb1:D, 8gb2:D, 8gb2:A, 8gb2:B, 8gb2:C, 7ltt:A, 7ltt:D, 7ltt:B, 7ltt:C, 7lu5:A, 7lu5:D, 7lu5:C, 7lu5:B, 7lu5:E, 7lu5:H, 7lu5:F, 7lu5:G, 7lu5:I, 7lu5:L, 7lu5:K, 7lu5:J, 7lu5:M, 7lu5:P, 7lu5:O, 7lu5:N, 4mz7:A, 4q7h:A, 4q7h:B, 4q7h:C, 4q7h:D, 4qfx:A, 4qfx:D, 4qfx:B, 4qfx:C, 4qfy:A, 4qfy:D, 4qfy:B, 4qfy:C, 4qfz:A, 4qfz:D, 4qfz:B, 4qfz:C, 4qg0:A, 4qg0:D, 4qg0:B, 4qg0:C, 4qg1:A, 4qg1:B, 4qg1:C, 4qg1:D, 4qg2:A, 4qg2:D, 4qg2:B, 4qg2:C, 4qg4:A, 4qg4:D, 4qg4:B, 4qg4:C, 8qxj:A, 8qxj:B, 8qxj:C, 8qxj:D, 8qxk:A, 8qxk:B, 8qxk:C, 8qxk:D, 8qxl:A, 8qxl:B, 8qxl:C, 8qxl:D, 8qxm:A, 8qxm:C, 8qxm:B, 8qxm:D, 8qxn:A, 8qxn:B, 8qxn:C, 8qxn:D, 8qxo:A, 8qxo:B, 8qxo:D, 8qxo:C, 4rxo:A, 4rxo:B, 4rxo:C, 4rxo:D, 4rxp:A, 4rxp:B, 4rxq:A, 4rxq:B, 4rxr:A, 4rxr:B, 4rxs:A, 4rxs:B, 7s2y:A, 7s2y:B, 7s2y:C, 7s2y:D, 8tdv:A, 8tdv:B, 8tdw:A, 8tdw:B, 4tnp:A, 4tnp:C, 4tnp:D, 4tnp:B, 4tnq:A, 4tnq:D, 4tnq:C, 4tnq:B, 4tnr:D, 4tnr:A, 4tnr:C, 4tnr:B, 4tnx:A, 4tnx:C, 4tnx:D, 4tnx:B, 4tny:A, 4tny:C, 4tny:B, 4tny:D, 4tnz:C, 4tnz:B, 4tnz:A, 4tnz:D, 4to0:A, 4to0:D, 4to0:C, 4to0:B, 4to1:A, 4to1:B, 4to1:C, 4to1:D, 4to2:A, 4to2:D, 4to2:B, 4to2:C, 4to3:A, 4to3:D, 4to3:B, 4to3:C, 4to4:A, 4to4:D, 4to4:B, 4to4:C, 4to5:A, 4to5:D, 4to5:C, 4to5:B, 4to6:A, 4to6:D, 4to6:B, 4to6:C, 6tx0:A, 6tx0:B, 6txa:A, 6txa:B, 6txa:D, 6txa:C, 6txa:E, 6txa:F, 6txa:H, 6txa:G, 6txa:I, 6txa:L, 6txa:J, 6txa:K, 6txa:M, 6txa:N, 6txa:P, 6txa:O, 6txc:A, 6txc:B, 6txc:D, 6txc:C, 6txc:E, 6txc:F, 6txc:H, 6txc:G, 6txc:I, 6txc:J, 6txc:L, 6txc:K, 6txc:M, 6txc:N, 6txc:P, 6txc:O, 6txe:A, 6txe:B, 6txe:C, 6txe:D, 6txe:E, 6txe:F, 6txe:G, 6txe:H, 6txe:I, 6txe:J, 6txe:K, 6txe:L, 6txe:M, 6txe:N, 6txe:P, 6txe:O, 6txf:A, 6txf:B, 3u1n:A, 3u1n:B, 3u1n:C, 3u1n:D, 6u6x:A, 6u6x:D, 6u6y:A, 6u6y:D, 6u6y:B, 6u6y:C, 6u6z:A, 6u6z:D, 6u6z:B, 6u6z:C, 7ujn:A, 7ujn:B, 7ujn:C, 7ujn:D, 6xu1:A, 6xu1:B, 6xu1:C, 6xu1:D, 6xu1:E, 6xu1:F, 6xu1:G, 6xu1:H, 6yom:A, 6yom:B, 4zwe:A, 4zwe:C, 4zwe:D, 4zwe:B, 4zwg:A, 4zwg:D, 4zwg:B, 4zwg:C
23 2gej:A 361 69 0.0365 0.0499 0.2609 0.88 2gek:A, 4n9w:A
24 5gvx:A 386 39 0.0243 0.0311 0.3077 1.5
25 6a9a:A 246 51 0.0406 0.0813 0.3922 2.0 1b49:A, 1b49:C, 1b5d:A, 1b5d:B, 1b5e:A, 1b5e:B, 6l18:A
26 1u8v:A 490 195 0.0974 0.0980 0.2462 2.2 1u8v:B, 1u8v:C, 1u8v:D
27 6g18:v 325 32 0.0284 0.0431 0.4375 6.7 6fdm:A, 6fdm:C, 6g51:v, 6hk6:A, 6hk6:B, 6hk6:I, 6hk6:C, 6hk6:D, 6hk6:E, 6hk6:F, 6hk6:G, 6hk6:H, 6hk6:J, 7vbt:A, 7vbt:B, 7wu0:v
28 8b5q:B 365 91 0.0446 0.0603 0.2418 7.9 8b5q:A, 8b5s:A, 8b5s:B, 8b62:A, 8b62:B, 8b63:A, 8b63:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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