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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKILKLQTLRGPNYWSIHRHKLVVMRLDLEDLYEKYTSDIPGFYKGLTEVLPSLVEHLCSPGVKGGFLTRVEKGTLIGHV
IEHVAIELQELAGMPVGFGRTRETSTTGVFQVVIEYENEQAGRYAARAAVRLCQSIVDTGTYPATELQQDLEDLKELKNQ
ASLGPSTEAIVKEAEARGIPWTQLGARFMIQFGYGVNQKKIQATLSNQTGILGVELACDKEGTKRILKDAGVPVPRGTVA
RYFDELQDAIEYVGGYPIVIKPLDGNHGRGITIDVKNWQEAEEAYDLARKASKTKTVIVERYYTGKDHRVLVVNGKVVAV
AERVPAHVVGNGKSTIAELIEETNRDPQRGDGHDNILTRITVDKSALDILGKQGYSIDSIPLKGKKCFLRATANLSTGGI
AVDRTDEIHPENVWLLSRVAKIIGLDIAGIDVVTEDISQPLREVEGVIVEVNAAPGFRMHVAPSRGLARNVAGAVMDMLF
PGSKNGRIPILSVTGTNGKTTTTRLLAHIIKQTGKVVGYTTTDGTYIGEYLAETGDNTGPQSAHLILSDPTVEVAVLETA
RGGILRSGLGFSSCEVGIVLNVTADHLGIGDIDTIEQLAKLKSVVAESVMPKGYAVLNAEDPLVAAMADRVKGQVAYFSM
DPNNELLLRHTEAGGLAAIYENGYISILKGDWTLRIEKAVNVPITMAGKAPFMIANALAACLAVFTQGVKIEHIRKGLST
FVASVDQTPGRMNMFNMGSYHALVDYAHNPASYEALGGFVRNWPGKRIGVVGGPGDRRDEDFVSLGELAADIFDEIIIKE
DDDTRGRPRGNAAELICQGVKQFLNGIKNSESKATYESILDETAAINTALDRAPIDGLVVILPESVNRAISLIEGRH

The query sequence (length=877) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7wae:B 877 877 1.0000 1.0000 1.0000 0.0 7wad:A, 7wad:B, 7wad:C, 7wad:D, 7wae:D, 7wae:A, 7wae:C, 7waf:A, 7waf:C, 7waf:D, 7waf:B
2 7lg5:A 871 877 0.6944 0.6992 0.6944 0.0 7lg5:B, 7lg5:C, 7lg5:D, 7lgj:A, 7lgj:B, 7lgj:C, 7lgj:D, 7lgq:A, 7lgq:B, 7lgq:C, 7lgq:D, 7txu:A, 7txu:B, 7txu:C, 7txu:D, 7txv:A, 7txv:B, 7txv:C, 7txv:D
3 7lgm:A 719 736 0.3398 0.4145 0.4049 2.04e-172 7lgm:B
4 8fxi:C 630 351 0.1437 0.2000 0.3590 4.09e-64 8fxi:D
5 4c12:A 493 339 0.0958 0.1704 0.2478 1.38e-12 4c13:A
6 8g6p:A 508 389 0.1060 0.1831 0.2391 4.49e-09
7 6vr7:A 485 295 0.0878 0.1588 0.2610 8.90e-09
8 7q8e:A 397 334 0.0889 0.1965 0.2335 9.65e-09 6gs2:B, 6gs2:D, 6h5e:B, 6h5e:D, 7q8e:C
9 6vr8:I 482 272 0.0764 0.1390 0.2463 2.00e-07 7ufp:I
10 4iwx:A 294 115 0.0422 0.1259 0.3217 1.49e-06 4iwy:A, 5zct:A, 5zct:B, 5zct:C, 5zct:D, 5zct:E, 5zct:F, 5zct:G, 5zct:H, 5zk6:A
11 8evy:B 317 143 0.0445 0.1230 0.2727 1.32e-05 8evy:A, 8evy:C, 8evz:A, 8evz:B, 8evz:C
12 7qyr:D 293 113 0.0422 0.1263 0.3274 2.87e-05 7qyr:A, 7qyr:B, 7qyr:C, 7qyr:E, 7qyr:F, 7qyr:G, 7qyr:H, 7qys:A, 7qys:B, 7qys:C, 7qys:D, 7qys:E, 7qys:G, 7qys:H, 7qys:J, 7qys:K, 7qys:M, 7qys:O
13 4bub:B 483 307 0.0901 0.1636 0.2573 4.71e-05 4bub:A
14 2vos:A 448 392 0.1015 0.1987 0.2270 5.34e-05 2vor:A
15 3vpd:A 281 139 0.0456 0.1423 0.2878 7.53e-05 3vpd:B
16 4hv4:A 465 296 0.0810 0.1527 0.2399 1.55e-04 4hv4:B
17 2wtz:B 508 408 0.1220 0.2106 0.2623 6.71e-04 2wtz:A, 2wtz:D, 2xja:A, 2xja:B, 2xja:C, 2xja:D
18 3zl8:A 427 308 0.0787 0.1616 0.2240 7.95e-04
19 4qf5:A 459 316 0.0832 0.1590 0.2310 0.004 4qdi:A, 4qf5:B, 4ziy:A
20 8egn:A 309 243 0.0650 0.1845 0.2346 0.005 9d9k:A, 8dof:A, 8egm:A, 8egm:B, 8egm:C, 8egm:D, 8egm:E, 8egm:F, 8egm:G, 8egm:H, 8egn:B, 8ewa:A, 8ewa:B, 6x9f:A, 6x9f:B, 6x9f:C, 6x9f:D, 6x9f:E, 6x9f:F, 6x9f:G, 6x9f:H, 6x9n:A, 6x9n:B, 6x9n:C, 6x9n:D, 6x9n:E, 6x9n:F, 6x9n:G, 6x9n:H
21 7ti7:A 442 100 0.0342 0.0679 0.3000 0.009
22 1w78:A 414 315 0.0821 0.1739 0.2286 0.018 1w7k:A
23 8evw:B 326 114 0.0365 0.0982 0.2807 0.018 8evw:A, 8evx:A
24 8evx:B 305 114 0.0365 0.1049 0.2807 0.022
25 3r5x:D 306 147 0.0410 0.1176 0.2449 0.032 3r5x:A, 3r5x:B
26 4fu0:A 343 96 0.0353 0.0904 0.3229 0.032 4fu0:B
27 8rth:A 666 97 0.0342 0.0450 0.3093 0.033 8rth:C, 8rth:E, 8rth:G, 8rth:I, 8rth:K
28 8dp2:A 446 110 0.0342 0.0673 0.2727 0.037 7u35:A, 7u35:B, 7u35:C
29 2jfg:A 439 107 0.0365 0.0729 0.2991 0.047 5a5f:A, 9bn8:A, 9bn9:A, 1eeh:A, 2jff:A, 2jfh:A, 1uag:A, 2uag:A, 3uag:A, 4uag:A, 2uuo:A, 2uup:A, 2vtd:A, 2vte:A, 8vw0:A, 8vw1:A, 8vw2:A, 2wjp:A, 2x5o:A, 2xpc:A, 2y1o:A, 2y66:A, 2y67:A, 2y68:A
30 7u56:A 346 103 0.0376 0.0954 0.3204 0.047 7u56:B
31 1gqy:B 469 333 0.1003 0.1876 0.2643 0.063 1gqy:A, 1p31:A, 1p31:B, 1p3d:A, 1p3d:B
32 2am1:A 454 323 0.0901 0.1740 0.2446 0.076 2am2:A, 3zm5:A, 3zm6:A
33 1eyz:A 389 89 0.0262 0.0591 0.2584 0.12 1eyz:B, 1ez1:A, 1ez1:B, 1kj8:A, 1kj8:B, 1kj9:A, 1kj9:B, 1kji:A, 1kji:B, 1kjj:A, 1kjj:B, 1kjq:A, 1kjq:B
34 4cvm:A 443 157 0.0479 0.0948 0.2675 0.12 4cvk:A, 4cvl:A
35 7z2b:K 308 116 0.0308 0.0877 0.2328 0.23
36 3ouu:A 446 148 0.0502 0.0987 0.2973 0.29 3ouu:B, 3ouz:A, 3ouz:B
37 5nri:A 311 124 0.0445 0.1254 0.3145 0.31 5nrh:A, 5nrh:B, 5nri:B
38 1e8c:B 497 323 0.0889 0.1569 0.2415 0.33 7b60:A, 7b60:B, 7b61:A, 7b61:B, 7b68:A, 7b68:B, 7b6g:BBB, 7b6i:B, 7b6j:A, 7b6j:B, 7b6k:A, 7b6k:B, 7b6l:A, 7b6l:B, 7b6m:B, 7b6n:B, 7b6p:A, 7b6p:B, 7b6q:B, 7b9e:A, 7b9e:B, 7b9w:BBB, 1e8c:A
39 1uc9:A 256 52 0.0217 0.0742 0.3654 1.4 1uc9:B
40 3vot:A 411 88 0.0296 0.0633 0.2955 1.6 3vot:B
41 3rfc:A 344 67 0.0228 0.0581 0.2985 2.0 4l1k:A, 4me6:A, 3r5f:A
42 5bpf:C 306 181 0.0479 0.1373 0.2320 2.1 5bpf:B, 5bpf:D, 5bph:A, 5bph:B, 5bph:C, 5bph:D, 5c1o:A, 5c1o:B, 5c1o:C, 5c1o:D, 5c1p:B, 5c1p:C, 5c1p:D
43 3orq:A 373 105 0.0319 0.0751 0.2667 2.3 3orq:B
44 1zvr:A 514 126 0.0376 0.0642 0.2619 2.5 1zsq:A
45 3i12:A 360 99 0.0331 0.0806 0.2929 2.8 3i12:B, 3i12:C, 3i12:D, 3q1k:A, 3q1k:B, 3q1k:C, 3q1k:D
46 6nop:B 262 88 0.0251 0.0840 0.2500 2.9 6non:B, 6noo:B, 6nop:A
47 3pyz:A 410 89 0.0308 0.0659 0.3034 3.3 3n2a:A, 3qcz:A
48 4c5a:A 306 116 0.0285 0.0817 0.2155 3.4 4c5a:B, 4c5b:A, 4c5b:B, 4c5c:A, 4c5c:B, 2dln:A, 1iov:A, 1iow:A
49 7kct:A 453 152 0.0468 0.0905 0.2697 4.6 7kbl:A, 7kbl:B, 7kc7:A, 7kct:B
50 1jbw:A 410 32 0.0148 0.0317 0.4062 5.3 1fgs:A, 1jbv:A
51 3ufx:B 378 67 0.0296 0.0688 0.3881 7.4 3ufx:E, 3ufx:G, 3ufx:I
52 1onx:A 389 22 0.0137 0.0308 0.5455 8.1 2aqo:A, 2aqo:B, 2aqv:A, 2aqv:B, 1onw:A, 1onw:B, 1onx:B, 1po9:A, 1po9:B, 1poj:A, 1poj:B, 1pok:B, 1pok:A, 1ybq:A, 1ybq:B
53 6pcm:A 793 29 0.0148 0.0164 0.4483 8.2 6pcm:B
54 7drp:A 312 101 0.0331 0.0929 0.2871 8.2 7drm:A, 7drm:B, 7drm:C, 7drm:D, 7drn:A, 7drn:B, 7drn:C, 7dro:A, 7dro:B, 7dro:C, 7dro:E, 7drp:C, 7drp:D, 7drp:B
55 6cq2:A 688 29 0.0148 0.0189 0.4483 9.0 6cqi:A
56 8czq:A 655 29 0.0148 0.0198 0.4483 9.3
57 5k2m:G 273 82 0.0274 0.0879 0.2927 9.9 5k2m:I, 5k2m:A, 5k2m:B, 5k2m:C, 5k2m:D, 5k2m:H, 5k2m:J
58 1myt:A 146 60 0.0205 0.1233 0.3000 9.9 2nrl:A, 2nrm:A, 2nx0:A, 3qm5:A, 3qm6:A, 3qm7:A, 3qm8:A, 3qm9:A, 3qma:A
59 6jlu:V 137 58 0.0228 0.1460 0.3448 9.9 8iwh:V, 8iwh:v, 6j3y:V, 6j3y:v, 6j3z:V, 6j3z:v, 6j40:V, 6j40:v, 8j5k:V, 8j5k:v, 6jlu:v, 7vd5:V, 7vd5:v

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218