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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKIAIPKERRPGEDRVAISPEVVKKLVGLGFEVIVEQGAGVGASITDDALTAAGATIASTAAQALSQADVVWKVQRPMTA
EEGTDEVALIKEGAVLMCHLGALTNRPVVEALTKRKITAYAMELMPRISRAQSMDILSSQSNLAGYRAVIDGAYEFARAF
PMMMTAAGTVPPARVLVFGVGVAGLQAIATAKRLGAVVMATDVRAATKEQVESLGGKFITVDDEFRKKQAEAVLKELVKT
DIAITTALIPGKPAPVLITEEMVTKMKPGSVIIDLAVEAGGNCPLSEPGKIVVKHGVKIVGHTNVPSRVAADASPLFAKN
LLNFLTPHVDKDTKTLVMKLEDETVSGTCVTRDGAIVHPALTG

The query sequence (length=363) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1f8g:A 382 379 1.0000 0.9503 0.9578 0.0 1f8g:B, 1f8g:C, 1f8g:D, 2frd:A, 2frd:B, 2fsv:A, 1hzz:A, 1l7e:A, 1l7e:D, 1nm5:A, 1nm5:B, 2oo5:A, 2oo5:B, 2oor:A, 2oor:B, 1ptj:A, 1u28:A, 1u28:B, 1u2d:A, 1u2d:B, 1u2g:A, 1xlt:A, 1xlt:B, 1xlt:D, 1xlt:E, 1xlt:H, 1xlt:G
2 1u2g:B 359 363 0.9890 1.0000 0.9890 0.0 2fr8:A
3 2bru:B 364 362 0.4463 0.4451 0.4475 1.17e-100 1x14:B, 1x15:B
4 3p2y:A 345 351 0.4518 0.4754 0.4672 2.25e-93
5 4j1t:E 373 370 0.4573 0.4450 0.4486 1.67e-89 4j16:A, 4j16:B, 4j1t:B, 4o9u:E, 4o9u:F
6 6qti:A 1038 387 0.4132 0.1445 0.3876 1.21e-77 1d4o:A, 1djl:A, 1djl:B, 1pt9:A, 1pt9:B, 6qti:B, 6que:A, 6que:B, 1u31:A, 1u31:B
7 2vhw:E 373 292 0.2700 0.2627 0.3356 1.34e-37 4lmp:A, 6o7f:A, 2vhv:A, 2vhv:B, 2vhw:A, 2vhw:B, 2vhw:C, 2vhw:D, 2vhw:F, 2vhx:A, 2vhx:B, 2vhx:C, 2vhx:D, 2vhx:E, 2vhx:F, 2vhz:A, 2vhz:B, 2voj:A, 2voj:C, 2voj:E
8 8hye:C 371 317 0.2893 0.2830 0.3312 2.61e-33 8hye:A, 8hye:B
9 1pjc:A 361 370 0.3168 0.3186 0.3108 3.63e-27 1say:A
10 8hyh:A 366 317 0.2810 0.2787 0.3218 1.29e-25
11 7xqm:B 253 92 0.0882 0.1265 0.3478 0.029 2d1y:A, 2d1y:B, 2d1y:C, 2d1y:D, 8pa2:A, 8pa2:B, 8pa2:C, 8pa2:D, 7xqm:A, 7xqm:C, 7xqm:D
12 7dcu:A 101 41 0.0358 0.1287 0.3171 0.030 7dci:A, 7dcu:C
13 3uh1:A 367 194 0.1267 0.1253 0.2371 0.046 2qrj:A, 2qrk:A, 3uha:A, 3uha:B
14 4a2c:A 346 78 0.0689 0.0723 0.3205 0.091 4a2c:B, 4uej:A, 4uej:B, 4uek:A, 4uek:B, 4ueo:A, 4ueo:B
15 2rir:E 298 157 0.1157 0.1409 0.2675 0.20 2rir:A, 2rir:B, 2rir:C, 2rir:D, 2rir:F, 2rir:G, 2rir:H
16 9gd1:W 849 85 0.0689 0.0294 0.2941 0.56
17 7tn2:W 895 85 0.0689 0.0279 0.2941 0.61 9gd2:W, 9gd3:W
18 4zgs:A 346 192 0.1267 0.1329 0.2396 0.66 4zgs:B, 4zgs:C, 4zgs:D, 4zgs:E, 4zgs:F, 4zgs:G, 4zgs:H
19 1o8c:A 324 66 0.0634 0.0710 0.3485 2.0 1o8c:B, 1o8c:C, 1o8c:D
20 1zq1:A 437 122 0.0882 0.0732 0.2623 3.1 1zq1:B
21 3qe3:A 351 72 0.0634 0.0655 0.3194 3.5
22 1qo8:A 564 37 0.0468 0.0301 0.4595 4.4 1qo8:D
23 2ag5:A 246 55 0.0468 0.0691 0.3091 6.2 2ag5:B, 2ag5:C, 2ag5:D
24 3nx4:A 324 88 0.0799 0.0895 0.3295 7.2 3nx4:B
25 7y8r:I 732 147 0.1047 0.0519 0.2585 8.0
26 4pve:A 490 109 0.0634 0.0469 0.2110 9.7 4pvh:A, 4pvj:A, 4pvk:A, 4pwb:A, 4pwc:A, 3tsh:A, 3tsj:A, 3tsj:B
27 3ugm:A 854 74 0.0551 0.0234 0.2703 9.7
28 3afo:A 360 81 0.0771 0.0778 0.3457 9.9 3afo:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218