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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MIYEGKAITVTALESGIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVENFKL
PDAELIAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLGIYPGFGGTVRLPRLIG
VDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAAALDLIKRAISGELDYKAKRQPKLEKLKLNAIEQMMAFETAKGF
VAGQAGPNYPAPVEAIKTIQKAANFGRDKALEVEAAGFAKLAKTSASNCLIGLFLNDQELKKKAKVYDKIAKDVKQAAVL
GAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLVGRVDKGRMTPAKMAEVLNGIRPTLSYGDFGNVDLVVEA
VVENPKVKQAVLAEVENHVREDAILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSDLAVATTVA
YAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKVMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGF
PDRMKDDRRSAIDALYEAKRLGQKNGKGFYAYEKKLVDSSVLEVLKPIVYEQRDVTDEDIINWMMIPLCLETVRCLEDGI
VETAAEADMGLVYGIGFPLFRGGALRYIDSIGVAEFVALADQYAELGALYHPTAKLREMAKNGQSFFG

The query sequence (length=708) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1wdl:A 715 715 1.0000 0.9902 0.9902 0.0 2d3t:A, 2d3t:B, 1wdk:A, 1wdk:B, 1wdl:B, 1wdm:A, 1wdm:B
2 6tnm:A 719 715 0.5692 0.5605 0.5636 0.0
3 6ysw:A 707 712 0.3559 0.3564 0.3539 4.65e-124
4 6iun:B 692 670 0.3065 0.3136 0.3239 1.79e-104 6iun:A
5 8oqs:B 735 709 0.3418 0.3293 0.3413 1.10e-94 4b3i:A, 4b3i:B, 4b3j:A, 4b3j:B, 7o4s:A, 7o4s:B, 7o4t:A, 7o4t:B, 7o4u:A, 7o4u:B, 7o4v:B, 7o4v:A, 8opu:A, 8opu:B, 8opv:A, 8opv:B, 8oql:A, 8oql:B, 8oqn:A, 8oqn:B, 8oqo:A, 8oqo:B, 8oqp:A, 8oqp:B, 8oqq:A, 8oqq:B, 8oqr:A, 8oqr:B, 8oqs:A, 8oqt:B, 8oqt:A, 8oqu:A, 8oqu:B, 8oqv:A, 8oqv:B, 8pf8:A, 8pf8:B
6 3zwa:A 727 688 0.2980 0.2902 0.3067 2.98e-78 5mgb:A, 5mgb:B, 5omo:A, 5omo:B, 2x58:A, 2x58:B, 6z5f:AAA, 6z5f:BBB, 6z5o:AAA, 6z5v:AAA, 6z5v:BBB, 6zib:AAA, 6zib:BBB, 6zic:AAA, 6zic:BBB, 3zw9:A, 3zw9:B, 3zwa:B, 3zwb:A, 3zwb:B, 3zwc:A, 3zwc:B
7 3k6j:A 430 383 0.1554 0.2558 0.2872 2.43e-53
8 4pzd:A 283 288 0.1582 0.3958 0.3889 1.75e-52 4pzd:B, 4pzd:C, 4pzd:D, 4pzd:E, 4pzd:F, 4pzd:G, 4pzd:H, 4pzd:I, 4pze:A, 4pze:B, 4pze:C, 4pze:D, 4pze:G, 4pze:E, 4pze:F, 4pze:H, 4pze:I
9 4kug:A 282 284 0.1582 0.3972 0.3944 4.55e-52 4kug:B, 4kug:C, 4kug:D, 4kuh:A, 4kuh:B, 4kuh:C, 4kuh:D, 4kuh:E, 4kuh:F, 4kuh:G, 4kuh:H
10 6aa8:E 281 283 0.1554 0.3915 0.3887 8.55e-52 6aa8:F
11 6aa8:E 281 86 0.0353 0.0890 0.2907 2.2 6aa8:F
12 1f12:A 293 294 0.1455 0.3515 0.3503 3.79e-44 1f0y:A, 1f0y:B, 1f17:A, 1f17:B, 3had:A, 3had:B, 2hdh:A, 2hdh:B, 3hdh:A, 3hdh:B, 3hdh:C, 1il0:A, 1il0:B, 1lsj:A, 1lsj:B, 1lso:A, 1lso:B, 1m75:A, 1m75:B, 1m76:A, 1m76:B
13 1f12:A 293 98 0.0325 0.0785 0.2347 0.018 1f0y:A, 1f0y:B, 1f17:A, 1f17:B, 3had:A, 3had:B, 2hdh:A, 2hdh:B, 3hdh:A, 3hdh:B, 3hdh:C, 1il0:A, 1il0:B, 1lsj:A, 1lsj:B, 1lso:A, 1lso:B, 1m75:A, 1m75:B, 1m76:A, 1m76:B
14 5zai:C 259 224 0.1158 0.3166 0.3661 1.50e-31 5zai:A, 5zai:B, 5zai:E
15 4om8:A 309 286 0.1271 0.2913 0.3147 1.40e-29 4om8:B
16 3h81:A 256 179 0.0862 0.2383 0.3408 1.09e-23 3h81:C, 3q0g:C, 3q0g:D, 3q0g:F, 3q0j:C, 3q0j:F
17 6eqo:A 1804 174 0.0904 0.0355 0.3678 1.02e-21 6eqo:B
18 5jbx:B 261 163 0.0876 0.2375 0.3804 4.44e-21 5jbx:A
19 1dub:A 260 192 0.0791 0.2154 0.2917 9.28e-20 1dub:B, 1dub:C, 1dub:E, 1dub:F, 1dub:D, 2dub:A, 2dub:B, 2dub:C, 2dub:E, 2dub:F, 2dub:D, 1ey3:A, 1ey3:B, 1ey3:C, 1ey3:D, 1ey3:E, 1ey3:F, 1mj3:A, 1mj3:B, 1mj3:C, 1mj3:E, 1mj3:F
20 4dyd:A 283 293 0.1172 0.2933 0.2833 3.27e-19 4e13:A
21 6slb:AAA 257 234 0.0989 0.2724 0.2991 4.11e-18 6sla:AAA, 6sla:BBB, 6sla:CCC, 6sla:DDD, 6sla:EEE, 6sla:FFF
22 2hw5:C 260 195 0.0763 0.2077 0.2769 7.43e-18
23 7bor:A 247 165 0.0664 0.1903 0.2848 1.23e-15 7bor:C
24 4izc:B 266 177 0.0706 0.1880 0.2825 4.21e-13 4izc:A, 4izd:A, 4izd:B
25 3p85:A 224 151 0.0678 0.2143 0.3179 9.51e-13
26 3pe8:A 219 109 0.0537 0.1735 0.3486 1.14e-12
27 1sg4:B 258 197 0.0847 0.2326 0.3046 1.16e-12
28 3f3s:A 312 207 0.0777 0.1763 0.2657 4.22e-12 3f3s:B
29 1xx4:A 254 197 0.0819 0.2283 0.2944 5.73e-12
30 1jxz:B 269 245 0.0791 0.2082 0.2286 1.03e-11 1jxz:A, 1jxz:C, 1nzy:A, 1nzy:B, 1nzy:C
31 7xwt:B 277 147 0.0650 0.1661 0.3129 6.15e-10 7xwv:A, 7xwv:B
32 4jvt:A 257 153 0.0551 0.1518 0.2549 6.37e-10 4omr:A
33 2vss:B 247 207 0.0692 0.1984 0.2367 1.00e-09 6l3p:A, 6l3p:B, 2vss:D, 2vss:E, 2vss:F, 2vsu:A, 2vsu:B, 2vsu:D, 2vsu:E, 2vsu:F
34 2a81:A 235 125 0.0537 0.1617 0.3040 8.50e-09
35 5duf:A 245 173 0.0678 0.1959 0.2775 1.27e-08 5dtw:A, 5dtw:D, 5du4:A, 5du6:A, 5du6:B, 5du6:C, 5du8:A, 5du8:B, 5du8:C, 5duc:A, 5duc:B, 5duc:C
36 6p5u:E 246 159 0.0664 0.1911 0.2956 1.27e-08 6p5u:A, 6p5u:B, 6p5u:C, 6p5u:D, 6p5u:F
37 3bpt:A 362 133 0.0579 0.1133 0.3083 1.84e-08
38 3adp:A 310 204 0.0749 0.1710 0.2598 7.51e-08
39 1szo:D 251 193 0.0706 0.1992 0.2591 1.32e-07 1szo:A, 1szo:B, 1szo:C, 1szo:E, 1szo:F, 1szo:G, 1szo:H, 1szo:I, 1szo:J, 1szo:K, 1szo:L
40 2j5s:A 250 216 0.0749 0.2120 0.2454 1.59e-07 2j5s:B
41 1ef9:A 261 194 0.0621 0.1686 0.2268 8.79e-07 6n92:A, 6n92:B, 6n92:C, 6n92:D, 6n92:E, 6n92:F, 6n93:A, 6n93:B, 6n93:C, 6n93:D, 6n93:E, 6n93:F, 6n94:A, 6n94:B, 6n94:C, 6n94:D, 6n94:E, 6n94:F, 6n95:A, 6n95:B, 6n95:C, 6n95:D, 6n95:E, 6n95:F, 6n96:A, 6n96:B, 6n96:C, 6n96:D, 6n96:E, 6n96:F, 6n97:A, 6n97:B, 6n97:C, 6n97:D, 6n97:E, 6n97:F
42 4i42:A 285 233 0.0791 0.1965 0.2403 1.01e-06 4els:A, 4els:B, 4els:C, 4els:D, 4els:E, 4els:F, 4elw:A, 4elw:B, 4elw:C, 4elw:D, 4elw:E, 4elw:F, 4elx:A, 4elx:B, 4elx:C, 4elx:D, 4elx:F, 3h02:A, 3h02:B, 3h02:C, 3h02:D, 3h02:E, 3h02:F, 4i42:F, 4i42:B, 4i42:D, 4i42:C, 4i42:E, 4i42:G, 4i42:L, 4i42:H, 4i42:J, 4i42:I, 4i42:K, 3t88:A, 3t88:E, 3t88:B, 3t88:F, 3t88:C, 3t88:D
43 4i4z:A 275 185 0.0678 0.1745 0.2595 1.62e-06 4eml:A, 4eml:B, 4eml:C, 4eml:D, 4eml:E, 4eml:F, 4i4z:F, 4i4z:B, 4i4z:D, 4i4z:C, 4i4z:E, 4i4z:G, 4i4z:H, 4i4z:I, 4i52:A, 4i52:B, 4i52:C, 4i52:D, 4i52:E, 4i52:F, 4i52:G, 4i52:H, 4i52:I
44 5kag:D 423 104 0.0565 0.0946 0.3846 3.13e-06 5kag:A, 5kag:B, 5kag:C, 5kag:E, 5kag:F, 5kag:G, 5kag:H, 5kag:I, 5kag:J, 5kag:K, 5kag:L, 5kah:A, 5kah:B, 5kah:C, 5kah:D, 5kah:E, 5kah:F, 5kah:G, 5kah:H, 5kah:I, 5kah:J, 5kah:K, 5kah:L, 5kaj:A, 5kaj:B, 5kaj:C, 5kaj:D, 5kaj:E, 5kaj:F, 5kaj:G, 5kaj:H, 5kaj:I, 5kaj:J, 5kaj:K, 5kaj:L, 2np9:A, 2np9:B, 2np9:C, 2pg8:A, 2pg8:B, 2pg8:C, 4ylh:A, 4ylh:B, 4ylh:C, 4ylh:D, 4ylh:E, 4ylh:F, 4ylh:G, 4ylh:H, 4ylh:I, 4ylh:J, 4ylh:K, 4ylh:L
45 3ome:C 247 185 0.0720 0.2065 0.2757 1.11e-05 3ome:A, 3ome:B, 3ome:D, 3ome:E, 3ome:F
46 3t3w:F 248 228 0.0819 0.2339 0.2544 2.46e-05 3t3w:A, 3t3w:B, 3t3w:C, 3t3w:D, 3t3w:E
47 3rrv:B 254 224 0.0763 0.2126 0.2411 4.50e-05 3rrv:A, 3rrv:C, 3rrv:D, 3rrv:E, 3rrv:F
48 2uzf:A 260 90 0.0381 0.1038 0.3000 2.25e-04
49 4hdt:A 340 272 0.0890 0.1853 0.2316 2.92e-04
50 6z1p:BI 1413 163 0.0593 0.0297 0.2577 0.009
51 4wio:A 525 186 0.0607 0.0819 0.2312 0.032 3uow:A
52 4jz7:A 285 95 0.0381 0.0947 0.2842 0.14 4jz7:B
53 4jz7:C 316 95 0.0395 0.0886 0.2947 0.16 4jz7:D, 4jz8:A, 4jz8:B, 4jz8:C, 4jz8:D, 4jz9:A, 4jz9:B, 4jz9:C, 4jz9:D, 4olc:A, 4olc:C
54 8g84:A 297 43 0.0240 0.0572 0.3953 0.17 8g84:B, 8g89:A, 8g89:B, 8g93:A, 8g93:B
55 8g9v:E 293 43 0.0226 0.0546 0.3721 0.39 8g9v:A, 8g9v:B, 8g9v:C, 8g9v:D, 8g9v:F, 8g9v:G, 8g9v:H
56 3n6s:A 344 51 0.0198 0.0407 0.2745 0.47 5cky:O, 5co0:O, 5crj:O, 5crk:O, 3mva:O, 3mvb:O, 3n7q:A
57 6ixx:A 463 176 0.0636 0.0972 0.2557 0.51 1g9k:A, 1h71:P, 1o0q:A, 1o0t:A, 1om6:A, 1om7:A, 1om8:A, 1omj:A, 3u1r:A
58 2bc0:A 473 112 0.0424 0.0634 0.2679 0.61 2bc0:B, 2bc1:A, 2bc1:B, 2bcp:A, 2bcp:B
59 4myp:A 121 58 0.0297 0.1736 0.3621 0.78 4myp:B
60 8rd8:E5 156 64 0.0339 0.1538 0.3750 1.3 8rdv:E5, 8rdw:E5
61 8cja:B 731 149 0.0523 0.0506 0.2483 1.7 8cjb:B, 8cjc:B, 8cmw:B, 7nyp:A, 7nyp:B, 7nys:A, 7nys:B, 7nz5:A, 7nz5:B, 7o0d:A, 1ru3:A, 7zkj:B, 7zkk:B, 7zkv:B
62 8wom:A 1217 80 0.0367 0.0214 0.3250 1.9 8woo:A, 8wp0:A
63 7w6b:A 782 84 0.0325 0.0294 0.2738 2.7 7vcn:C, 7vcn:A, 7vcn:D, 7vcn:B
64 4urh:C 264 80 0.0325 0.0871 0.2875 2.8 3cur:A, 3cur:B, 3cur:C, 3cus:A, 3cus:B, 3cus:C, 1frf:S, 3h3x:A, 3h3x:B, 3h3x:C, 4ucq:A, 4ucq:B, 4ucq:C, 4ucw:A, 4ucw:B, 4ucw:C, 4ucx:A, 4ucx:B, 4ucx:C, 4ud2:A, 4ud2:B, 4ud2:C, 4ud6:A, 4ud6:B, 4ud6:C, 4ue2:A, 4ue2:B, 4ue2:C, 4ue6:A, 4ue6:B, 4ue6:C, 4ueq:A, 4ueq:B, 4ueq:C, 4ueq:D, 4ueq:E, 4ueq:F, 4uew:A, 4uew:B, 4uew:C, 4upe:A, 4upe:B, 4upe:C, 4upv:A, 4upv:B, 4uql:A, 4uql:B, 4uqp:A, 4uqp:B, 4urh:A, 4urh:B, 1yqw:A, 1yqw:B, 1yqw:C, 1yrq:A, 1yrq:B, 1yrq:C, 1yrq:D, 1yrq:F, 1yrq:G
65 6ra9:B 458 97 0.0424 0.0655 0.3093 5.0 8b6z:A, 4c0s:A, 4c0s:B, 8g5z:EF, 8g60:EF, 8g6j:EF, 5lzs:jj, 6ra9:A, 6zmo:CD
66 1gvi:B 588 68 0.0297 0.0357 0.3088 5.9 1gvi:A
67 8cd1:e 156 64 0.0339 0.1538 0.3750 6.1 6spc:e, 6spe:e, 6spf:e, 6spg:e, 7unr:e, 7unu:e, 7unv:e, 7unw:e
68 2uzz:B 372 182 0.0523 0.0995 0.2033 6.3 2uzz:A, 2uzz:C, 2uzz:D
69 3rj8:A 473 38 0.0198 0.0296 0.3684 7.2 3rja:A
70 6k33:a4 336 63 0.0311 0.0655 0.3492 9.3 6k33:a1, 6k33:c6, 6k33:a2, 6k33:a3, 6k33:a5, 6k33:a6, 6k33:b1, 6k33:b2, 6k33:b3, 6k33:b4, 6k33:b5, 6k33:b6, 6k33:c1, 6k33:c2, 6k33:c3, 6k33:c4, 6k33:c5
71 7z0s:E 532 86 0.0353 0.0470 0.2907 9.5 7z0t:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218