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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MIPIDDDKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRN
VVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLGISLDEIKKIEEIALKVNEILKDYLAKKGIILVDF
KLEFGKDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERITGEKPEF

The query sequence (length=224) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4o7n:A 233 224 1.0000 0.9614 1.0000 6.43e-162 4o7l:A, 4o7r:A, 4o7s:A, 4o7t:A, 4o7v:A, 4o7w:A, 4o7y:A, 4o7z:A, 4o81:A, 4o81:B, 4o82:A, 4o82:B, 4o83:A, 4o83:B, 4o84:A, 4o84:B, 4o86:A, 3u54:A, 3u54:B
2 3nua:B 237 213 0.5000 0.4726 0.5258 4.88e-74 3nua:A
3 2z02:A 242 215 0.5179 0.4793 0.5395 5.66e-74 2yzl:A, 2z02:B
4 2ywv:A 237 215 0.4955 0.4684 0.5163 1.83e-70 2ywv:B
5 4fe2:B 235 214 0.4509 0.4298 0.4720 8.15e-61 4fe2:A, 4fgr:A, 4fgr:B, 4nye:A, 4nye:B
6 2gqr:A 237 212 0.4107 0.3882 0.4340 6.44e-55 2gqr:B, 2gqs:A, 2gqs:B
7 7ale:A 419 200 0.3036 0.1623 0.3400 6.38e-26 7ale:B, 6yb8:A, 6yb8:B, 6yb9:A, 6yb9:B
8 1obg:A 305 241 0.3259 0.2393 0.3029 2.63e-20 2cnq:A, 2cnu:A, 2cnv:A, 1obd:A
9 6yx3:A 297 268 0.3438 0.2593 0.2873 6.24e-19 6yy6:A, 6yy7:A, 6yy8:A, 6yy9:A, 6yya:A, 6yyb:A, 6yyc:A, 6yyd:A, 6z0q:A, 6z0r:A
10 3l2n:A 376 96 0.1027 0.0612 0.2396 0.46 3l2n:B
11 8i9r:Cg 233 58 0.0804 0.0773 0.3103 1.2 8i9t:Cg
12 1ynp:B 298 100 0.1339 0.1007 0.3000 1.9 1ynp:A, 1ynq:A, 1ynq:B
13 7d80:5 432 27 0.0536 0.0278 0.4444 2.1 7d6z:h, 1w2b:5
14 5lu4:A 850 28 0.0580 0.0153 0.4643 3.0 5lu4:B
15 5jvl:A 874 28 0.0580 0.0149 0.4643 3.1 5jvj:A, 5jvl:C, 5jvl:D, 5jvn:A
16 3l76:A 585 59 0.0714 0.0274 0.2712 4.1 3l76:B
17 5th5:A 241 79 0.0848 0.0788 0.2405 4.2 5tgs:A, 5tgs:B, 5th5:B, 5th5:C, 5th5:D
18 9bh5:Cd 105 50 0.0714 0.1524 0.3200 7.5 9cai:Cd
19 4epm:A 554 69 0.0759 0.0307 0.2464 7.7 4eq4:A, 4eq4:B, 4eql:A, 4eql:B, 4l39:A, 4l39:B, 6oms:A, 6oms:B
20 4prl:A 330 85 0.0982 0.0667 0.2588 7.8 4prl:B
21 4ewv:B 492 69 0.0759 0.0346 0.2464 7.9 4ewv:A
22 4pet:A 329 55 0.0848 0.0578 0.3455 8.0 4pet:B
23 3haz:A 983 55 0.0804 0.0183 0.3273 9.9 6bsn:A, 6bsn:B, 3haz:B, 4q71:A, 4q71:B, 4q72:A, 4q72:B, 4q73:A, 4q73:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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