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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRT
IAPIIGRTAAQCLEHYEFLLDKAAQPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAA
LQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDK
QHLKRKKESDLPSAILQTSADVDARKQAIRDAERVKEMKRMHLQKSEELIKKEMITMLHYDLLHHKEELKKAQDVLVQEM
EVVKQGMSHGESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHE
DSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLKS

The query sequence (length=441) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6qdv:O 441 441 1.0000 1.0000 1.0000 0.0 7w59:L, 7w5a:L, 7w5b:L
2 9fmd:L 555 554 0.9955 0.7910 0.7924 0.0 8c6j:O, 7dvq:L, 6ff4:L, 8i0p:L, 8i0r:L, 6zym:L
3 8ro2:L 555 563 0.9342 0.7423 0.7318 0.0 7abi:L
4 8i0u:L 387 436 0.8707 0.9922 0.8807 0.0 8i0v:L
5 6icz:L 454 455 0.8753 0.8502 0.8484 0.0 5xjc:L
6 6id0:L 475 475 0.8776 0.8147 0.8147 0.0 6id1:L
7 8i0w:L 419 454 0.7982 0.8401 0.7753 0.0 5yzg:L
8 8ch6:P 330 439 0.7166 0.9576 0.7198 0.0 8i0t:L, 7qtt:P
9 5mqf:L 336 339 0.5760 0.7560 0.7493 3.18e-156
10 5mqf:L 336 101 0.2290 0.3006 1.0000 5.48e-62
11 8ro1:L 623 237 0.3673 0.2600 0.6835 1.49e-107 8ro0:L
12 8ro1:L 623 184 0.1361 0.0963 0.3261 2.76e-17 8ro0:L
13 8i0s:L 169 206 0.3810 0.9941 0.8155 1.09e-105
14 5z56:L 342 273 0.3900 0.5029 0.6300 4.11e-98 5z57:L, 5z58:L
15 5z56:L 342 103 0.2336 0.3012 1.0000 1.29e-69 5z57:L, 5z58:L
16 3jb9:W 426 196 0.3152 0.3263 0.7092 1.23e-85
17 3jb9:W 426 79 0.0499 0.0516 0.2785 1.8
18 6exn:O 320 214 0.2676 0.3688 0.5514 1.25e-72 6bk8:S
19 7b9v:O 280 208 0.2449 0.3857 0.5192 3.40e-62
20 5lj5:O 283 207 0.2404 0.3746 0.5121 1.40e-60
21 6j6g:c 436 210 0.2472 0.2500 0.5190 2.95e-60 6j6h:c, 6j6n:c, 6j6q:c, 5y88:J, 5ylz:J
22 5gmk:c 436 210 0.2472 0.2500 0.5190 9.82e-60 5lj3:O, 5mps:O, 5mq0:O, 5wsg:c
23 7dco:L 435 210 0.2132 0.2161 0.4476 1.15e-49
24 5gm6:c 415 210 0.2132 0.2265 0.4476 4.22e-49
25 1h88:C 152 140 0.1043 0.3026 0.3286 2.75e-12 1h89:C, 1h8a:C, 1mse:C, 1msf:C
26 1h88:C 152 97 0.0771 0.2237 0.3505 1.93e-11 1h89:C, 1h8a:C, 1mse:C, 1msf:C
27 1h88:C 152 58 0.0499 0.1447 0.3793 0.12 1h89:C, 1h8a:C, 1mse:C, 1msf:C
28 6kks:A 106 102 0.0794 0.3302 0.3431 5.71e-12
29 3zqc:J 119 85 0.0703 0.2605 0.3647 7.00e-12 3zqc:A, 3zqc:D, 3zqc:G
30 3osg:A 110 79 0.0726 0.2909 0.4051 4.47e-10 3osf:A, 3osf:D, 3osg:D
31 2kdz:A 107 54 0.0454 0.1869 0.3704 1.83e-07
32 8ity:4 365 103 0.0771 0.0932 0.3301 5.84e-05 8iue:4, 8iuh:4
33 8ity:4 365 95 0.0748 0.0904 0.3474 9.65e-05 8iue:4, 8iuh:4
34 8ity:4 365 76 0.0635 0.0767 0.3684 2.70e-04 8iue:4, 8iuh:4
35 8ity:4 365 102 0.0658 0.0795 0.2843 0.53 8iue:4, 8iuh:4
36 7zwc:c 303 76 0.0635 0.0924 0.3684 6.97e-05 7zwd:c, 7zx7:c, 7zx8:c, 7zxe:c
37 7zwc:c 303 102 0.0658 0.0957 0.2843 0.24 7zwd:c, 7zx7:c, 7zx8:c, 7zxe:c
38 5eyb:A 340 104 0.0862 0.1118 0.3654 9.96e-05 5eyb:B
39 7xur:A 307 103 0.0771 0.1107 0.3301 1.40e-04
40 7xur:A 307 95 0.0748 0.1075 0.3474 2.15e-04
41 7xur:A 307 106 0.0794 0.1140 0.3302 3.96e-04
42 7xur:A 307 102 0.0658 0.0945 0.2843 1.2
43 8ox1:M 65 45 0.0408 0.2769 0.4000 0.90 1iv6:A, 8ox1:L, 1w0t:A, 1w0t:B
44 4qsh:C 1081 138 0.0839 0.0342 0.2681 1.0 4qsh:A, 4qsh:D, 4qsh:B, 4qsk:A, 4qsk:B
45 7c4p:A 55 43 0.0363 0.2909 0.3721 1.3 7c4p:B, 7c4q:A, 7c4q:B, 7c4r:A, 7c4r:B
46 9ax8:z 509 57 0.0431 0.0373 0.3333 5.5 3jcj:f, 3jcn:b, 5me0:W, 5me1:W, 6o7k:f, 6o9k:z
47 6fb3:A 1836 92 0.0544 0.0131 0.2609 9.3 6fb3:B, 6fb3:C, 6fb3:D, 6ska:A, 6ske:A, 6ske:C
48 1vfc:A 63 42 0.0340 0.2381 0.3571 9.3 3sjm:A, 3sjm:B, 1w0u:A, 1w0u:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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