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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MIDLKQYEFWFLVGSQYLYGLETLKKVEQQASKIVDSLNDDPIFPSKIVLKPVLKSSSEITEIFEKANADPKCAGVIVWM
HTFSPSKMWIRGLSINKKPLLHLHTQYNREIPWDTIDMDYMNLNQSAHGDREHGFIHARMRLPRKVVVGHWEEKEVREKI
AKWMRVACAIQDGRMGQIVRFGDNMREVASTEGDKVEAQIKLGWSINTWGVGELAERVKAVPEREVEELLKEYREKYIMP
EDEYSLKAIREQAKIEIALREFLAAANAVGFTTTFEDLHDLPQLPGLAVQRLMEEGYGFGAEGDWKAAGLVRAIKVMGTS
LPGGTSFMEDYTYHLTPGNELVLGAHMLEVCPTIAKEKPRIEVHPLSIGGKADPARLVFDGQEGPAVNASIVDMGNRFRL
VVNKVLSVPIERKMPKLPTARVLWKPLPDFKRATTAWILAGGSHHTAFSTAIDVEYLIDWAEALEIEYVVIDENLDLEDF
KKELRWNELYWGLLK

The query sequence (length=495) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ch3:B 495 495 1.0000 1.0000 1.0000 0.0 7ch3:C, 7ch3:D, 7ch3:E, 7ch3:I, 7ch3:F, 7ch3:G, 7ch3:H, 7ch3:J, 7ch3:K, 7ch3:L, 7cwv:A, 7cwv:B, 7cwv:C, 7cwv:D, 7cwv:E, 7cwv:F, 7cwv:G, 7cwv:H, 7cwv:I, 7cwv:J, 7cwv:K, 7cwv:L
2 7ch3:A 469 495 0.9475 1.0000 0.9475 0.0
3 4r1q:E 496 495 0.6162 0.6149 0.6162 0.0 4r1p:A, 4r1p:B, 4r1p:C, 4r1p:D, 4r1p:E, 4r1p:F, 4r1q:A, 4r1q:D, 4r1q:B, 4r1q:F, 4r1q:C
4 7cyy:C 497 495 0.5960 0.5936 0.5960 0.0 7cx7:A, 7cx7:B, 7cx7:C, 7cx7:D, 7cx7:E, 7cx7:F, 7cyy:A, 7cyy:B, 7cyy:D, 7cyy:E, 7cyy:F
5 7chl:A 498 495 0.6061 0.6024 0.6061 0.0 7chl:B, 7chl:C, 7chl:D, 7chl:E, 7chl:F, 7chl:G, 7chl:H, 7chl:I, 7chl:J, 7chl:K, 7chl:L, 7cxo:A, 7cxo:B, 7cxo:C, 7cxo:D, 7cxo:E, 7cxo:F
6 4f2d:A 498 498 0.5495 0.5462 0.5462 0.0 4f2d:B, 4f2d:C, 2hxg:A, 2hxg:B, 2hxg:C
7 2evx:A 382 45 0.0303 0.0393 0.3333 0.58
8 7kya:A 1174 94 0.0545 0.0230 0.2872 1.3 7ky5:A, 7ky7:A, 7ky8:A, 7ky9:A
9 7eu1:A 1065 70 0.0424 0.0197 0.3000 2.2
10 7qei:A 291 35 0.0222 0.0378 0.3143 4.7
11 8xku:B 845 132 0.0667 0.0391 0.2500 4.9 8xkv:B
12 1vli:A 358 97 0.0465 0.0642 0.2371 5.1
13 3twb:C 417 71 0.0404 0.0480 0.2817 6.7 4ihc:A, 4ihc:G, 3twa:A, 3twa:B, 3twa:C, 3twa:D, 3twa:E, 3twb:A, 3twb:B, 3twb:D, 3twb:E
14 6b4h:A 318 62 0.0364 0.0566 0.2903 7.9 6b4h:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218