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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASEAAAAAGAAAAAKESWQLRKAVSEIGEDVDYDEELYVAGNMVIW
SKGSKSQALAVYKAFTVDSPVQQALWCDFIISEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFERSP
LPTMFSMLHPLDEITPLVCKAQYVVDHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKAEEEAAAAAAAAAGGFAAAA
PIVPELCIDHLWAAAQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESTALIFGSVTNIPAKDAAPVEKIDTMLVLEG
SGNLVLYTGVVRVGKVFIPATYIHSIRDPVHNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKW
YNVHSAPGGASYHSEWNLFVTCLMNMMGYTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELLVQLARDLKLGPYVDHYY
RDYPTLASEPPSIYQWVSSCLKGEGAPPYPYLPGICERSRLVVLSIALYILSSLAERLVVWMTNVGFILRDLETLPFGIA
LPIRDAIYHCREQPASDWPEAVCLLIGRQDLSAADDGMNDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELS
EHEFIEEKENRLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFH
NGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLG
TMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYATDRESYSLAA
GLALGMVCLGHGSNLIGMSALNVPEQLYQYMVGGHSPSYQIKEGDTLNVDVTCPGATLALAMIYLKTNNRSIADWLRAPD
TMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAF
NCLHKFAKDFMTYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLL
FLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVLYKGTQWYE
QTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLTQHLKSILSKDGVLYVKLRAGQLSYKEDASEARAFKSAFTSDPAL
LSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSELWQIKLVLEFFSSRSHQ
FMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSPLESQLSMLACFAVYHSVPAPAAAAAAAAAAAAAAAAAAAAAAAA
A

The query sequence (length=1441) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5a31:A 1441 1441 1.0000 1.0000 1.0000 0.0 5g04:A, 4ui9:A
2 6tnt:A 1583 1574 0.9396 0.8553 0.8602 0.0 5g05:A, 6tm5:A
3 7qe7:A 1648 1101 0.6766 0.5916 0.8856 0.0
4 7qe7:A 1648 465 0.2727 0.2385 0.8452 0.0
5 8bd3:6 217 123 0.0229 0.1521 0.2683 0.059 8bd3:0
6 6jiz:C 295 60 0.0139 0.0678 0.3333 2.4 6jit:B, 6jit:C, 6jiz:B
7 7wb0:A 797 88 0.0153 0.0276 0.2500 2.6
8 3bts:B 390 43 0.0090 0.0333 0.3023 2.8 3bts:A
9 7abg:g 93 46 0.0125 0.1935 0.3913 2.9 7a5p:n, 7abg:n, 7abi:n, 7abi:g, 6ah0:V, 6ahd:b, 7b0y:k, 8c6j:l, 8c6j:c, 8ch6:k, 8ch6:5, 7dvq:c, 7dvq:j, 9fmd:c, 9fmd:j, 8h6e:5b, 8h6e:4b, 8h6j:5b, 8h6j:4b, 8h6k:5b, 8h6l:5b, 8i0p:b, 8i0p:n, 8i0r:b, 8i0r:n, 8i0s:b, 8i0s:n, 8i0t:b, 8i0t:n, 8i0u:b, 8i0u:n, 8i0v:b, 8i0v:n, 8i0w:b, 8i0w:j, 6icz:j, 6id0:j, 6id1:j, 5mqf:g, 5o9z:n, 5o9z:g, 4pjo:C, 4pjo:c, 4pjo:Q, 4pjo:q, 8q7q:a, 8q7v:a, 8q7w:a, 8q7x:a, 8q91:i, 6qdv:l, 6qdv:h, 8qo9:21, 8qo9:51, 8qo9:41, 7qtt:k, 6qw6:41, 6qw6:51, 6qx9:11, 6qx9:51, 6qx9:21, 6qx9:41, 8qxd:21, 8qxd:41, 8qxd:51, 8qzs:51, 8qzs:21, 8r08:11, 8r08:41, 8r08:21, 8r08:51, 8r09:21, 8r09:51, 8r09:41, 8r0a:51, 8r0a:21, 8r0a:41, 8r0b:21, 8r0b:41, 8r0b:51, 8rc0:i, 8rm5:21, 8rm5:51, 8rm5:41, 8ro2:c, 7vpx:h, 7w59:c, 7w59:j, 7w5a:c, 7w5a:j, 7w5b:c, 7w5b:j, 4wzj:C, 4wzj:J, 4wzj:Q, 4wzj:CC, 4wzj:JJ, 4wzj:QQ, 4wzj:CCC, 4wzj:JJJ, 4wzj:QQQ, 4wzj:CCCC, 4wzj:JJJJ, 4wzj:QQQQ, 5xjc:c, 5xjc:j, 8y6o:b, 8y6o:i, 8y6o:p, 8y7e:j, 5yzg:c, 5yzg:j, 5z56:c, 5z56:j, 5z57:c, 5z57:j, 5z58:c, 5z58:j
10 5dl5:A 416 80 0.0167 0.0577 0.3000 4.5
11 7way:A 960 88 0.0153 0.0229 0.2500 5.6 7waz:A, 7wb1:A
12 5ein:A 344 32 0.0118 0.0494 0.5312 6.6 5ein:B, 5eio:A, 5eio:B, 2ozp:A
13 5y7z:A 312 40 0.0076 0.0353 0.2750 8.8 4c57:A, 4c57:B, 5y7z:B, 5y80:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218