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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MHLTARGLTLDLSRPQVMGILNVTPDSFSDGGCHNNLDQALQHAQRMLSAGATLIDIGGESTRPGAAEVSEQEELDRVVP
VVEALAQRFDVWLSVDTSKAAVITESAHAGAHLINDIRSLQEPGALEAAAKTGLPVCLMHMQGQPKNMQHSPYYDDLMTD
INRFFQHHIERCVAAGIAKNKLLLDPGFGFGKNLAHNYQLLAHLSELHHFELPLLVGMSRKSMVGQLLNVPPQQRVIGSV
ACAVIAAMQGAQIIRVHDVKETVEAMCIVEATRSA

The query sequence (length=275) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3tyz:B 276 275 1.0000 0.9964 1.0000 0.0 5jq9:A, 5jq9:B, 3tyu:A, 3tyz:A, 3tzf:A, 3tzf:B
2 3tyu:B 238 275 0.8545 0.9874 0.8545 1.87e-162
3 1aj0:A 282 275 0.7491 0.7305 0.7491 1.70e-154 1aj2:A, 7tq1:A, 7tq1:B, 5u0v:A, 5u0w:A, 5u0w:B, 5u0y:A, 5u0y:B, 5u0z:A, 5u0z:B, 5u10:A, 5u10:B, 5u11:A, 5u11:B, 5u12:A, 5u12:B, 5u13:A, 5u13:B, 5u14:A, 5u14:B, 5v79:A, 5v79:B, 5v7a:A, 5v7a:B
4 5u0v:B 249 275 0.6582 0.7269 0.6582 5.11e-117
5 6day:D 273 274 0.4909 0.4945 0.4927 4.99e-87 6day:A, 6day:B, 6day:C, 6ofw:A, 6ofw:B, 6q62:A, 6q62:C, 6q62:D, 6q62:B
6 6pz2:A 263 260 0.4145 0.4335 0.4385 3.44e-76
7 3tr9:A 277 266 0.4218 0.4188 0.4361 4.08e-73 3tr9:B, 3tr9:C, 3tr9:D
8 2y5s:B 281 276 0.4582 0.4484 0.4565 1.10e-65 2y5s:A
9 6omz:A 274 267 0.3782 0.3796 0.3895 4.29e-58
10 2dza:B 257 271 0.3964 0.4241 0.4022 6.24e-56 2dzb:A, 2dzb:B
11 3h2a:B 277 255 0.3673 0.3646 0.3961 7.13e-54 4d8a:A, 4d8a:B, 4d8z:A, 4d8z:B, 4d9p:A, 4d9p:B, 4daf:A, 4daf:B, 4dai:A, 4dai:B, 4db7:A, 4db7:B, 3h21:A, 3h21:B, 3h22:A, 3h22:B, 3h23:A, 3h23:B, 3h24:A, 3h24:B, 3h26:A, 3h26:B, 3h2a:A, 3h2c:A, 3h2c:B, 3h2e:B, 3h2f:A, 3h2f:B, 3h2m:A, 3h2m:B, 3h2n:A, 3h2n:B, 3h2o:A, 3h2o:B, 4nil:A, 4nir:A, 4nir:B, 4nl1:A, 4nl1:B, 1tww:A, 1tww:B, 1twz:A, 1twz:B, 1tx0:A, 1tx0:B, 1tx2:A, 1tx2:B, 3tya:A, 3tya:B, 3tyb:A, 3tyb:B, 3tyc:A, 3tyc:B, 3tyd:A, 3tyd:B, 3tye:A, 3tye:B
12 1eye:A 256 268 0.3564 0.3828 0.3657 2.66e-47
13 8d5h:B 274 255 0.3200 0.3212 0.3451 8.74e-45 8d5g:A, 8d5g:B, 8d5h:A, 8d5i:A, 8d5i:B
14 8scd:A 264 262 0.3127 0.3258 0.3282 3.27e-44 7s2m:A, 7s2m:B, 7s2m:C
15 6clv:C 257 251 0.3200 0.3424 0.3506 3.07e-41 1ad4:A, 6clv:A, 6clv:B
16 6ucz:B 265 253 0.3055 0.3170 0.3320 1.54e-38 6ucz:A
17 7s2k:A 268 261 0.3127 0.3209 0.3295 5.45e-36 7s2k:B
18 6jwz:B 565 270 0.3164 0.1540 0.3222 3.75e-32 6jwr:A, 6jwr:B, 6jwv:A, 6jww:A, 6jww:B, 6jwx:A, 6jwy:A, 6kcl:A, 6kcm:A
19 5z79:B 562 280 0.3091 0.1512 0.3036 4.03e-32
20 6jwq:B 590 282 0.3164 0.1475 0.3085 4.31e-32 6jwq:A, 6jws:A, 6jws:B, 6jwt:A, 6jwt:B, 6jwu:A, 6jwz:A, 6kck:A, 6kck:B, 6kcm:B
21 5z79:C 599 296 0.3200 0.1469 0.2973 1.57e-30 5z79:A, 5z79:D, 5z79:E, 5z79:F
22 2vef:A 279 287 0.3491 0.3441 0.3345 1.70e-30 2veg:A
23 2bmb:A 513 320 0.3200 0.1715 0.2750 2.03e-30
24 7s2i:A 264 257 0.2764 0.2879 0.2957 5.20e-29 7s2i:B
25 6kcl:B 545 264 0.2909 0.1468 0.3030 3.26e-25 6jwu:B, 6jwv:B, 6jwx:B, 6jwy:B
26 8sl9:A 422 216 0.2291 0.1493 0.2917 1.53e-18 4pzv:A
27 3mco:A 397 216 0.2145 0.1486 0.2731 2.48e-13 3mcn:B, 3mco:B
28 3mcm:A 368 217 0.2109 0.1576 0.2673 1.01e-07 3mcn:A
29 4kpu:B 263 62 0.0691 0.0722 0.3065 0.44 4l2i:B
30 5mcp:E 387 66 0.0727 0.0517 0.3030 1.1 5mcp:G
31 7kdf:A 270 24 0.0436 0.0444 0.5000 6.3
32 8c7f:A 772 70 0.0691 0.0246 0.2714 6.8 7zb3:A, 7zb3:B, 7zdy:W, 7zdy:Y, 7zgz:Y
33 7zgz:X 753 70 0.0691 0.0252 0.2714 7.2 8c7f:B
34 4g8s:A 182 43 0.0509 0.0769 0.3256 8.8 4g8s:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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