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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MGVIVELIDHTSAIAAAKDRADLVERLRAAKARISDPQIRVVIAGQLKQGKSQLLNSLLNIPVARVGDDESTVLATVVSY
GEQASARLVVARPDGAEPELIEIPPSEVTTDLRRAPQASGRQVLRVEVTAPSPLLKGGLAFVDTPGVGGHGQPHLSATLG
LLPDADAMLMISDTSQEFTEPEMKFIRQALEICPVAAIVATKTDLYPHWRQIVDANIAHLQRAGLNVPVIPASSVLRSHA
ISLNDKELNEESNFPAIVKFLSEHVLSRQNDRIRDQIVDEIRSAAEHLLLAVESELSSFNDPGERERLTAELERRKQEAQ
DALQQTALWQQVLSDGIADLTADVDHDLRHRFRIIAAHTEKVIDGCDPTLHWAEIGAELEDAVATAVGDNFVWAYQRAEA
LAAEVARTFTEAGLDAVQMPQIDYGGVLMFGMLTSFAGLGMFNPLSLGAGFVLGRKAYKEDMENRMLRVRNEAKANVRKF
VDDVAFVVGKESRDRLKGIQRQLRDHYREIANQTTRSLNESLQAAIAAAKVEEAERNTRVKELERQQNILKQVVDHAAKL
A

The query sequence (length=561) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6j72:A 561 561 1.0000 1.0000 1.0000 0.0
2 5oxf:B 591 264 0.1034 0.0981 0.2197 1.05e-07
3 5oxf:A 703 264 0.1034 0.0825 0.2197 1.13e-07
4 2j68:A 680 179 0.0766 0.0632 0.2402 3.14e-06 2w6d:A, 2w6d:B
5 5oxf:C 601 296 0.1266 0.1181 0.2399 2.49e-05 5oxf:D
6 7ase:5 421 156 0.0749 0.0998 0.2692 0.062
7 6jfk:A 428 174 0.0642 0.0841 0.2069 0.50 6jfm:A, 6jfm:B
8 2vk1:A 562 80 0.0428 0.0427 0.3000 0.78 1pvd:A, 1pvd:B, 1pyd:A, 1pyd:B, 1qpb:A, 1qpb:B, 2vk1:B, 2vk1:C, 2vk1:D, 2vk8:A, 2vk8:B, 2vk8:C, 2vk8:D, 2w93:A, 2w93:B, 2w93:C, 2w93:D
9 4cid:A 497 49 0.0303 0.0342 0.3469 1.0 2qpt:A
10 4xvi:A 647 72 0.0357 0.0309 0.2778 2.4 4xvk:A, 4xvl:A, 4xvm:A
11 7am2:BU 463 39 0.0250 0.0302 0.3590 3.6
12 9em9:A 512 94 0.0410 0.0449 0.2447 3.9 9em9:B
13 2i74:A 180 56 0.0303 0.0944 0.3036 4.1 2i74:B
14 1xzq:A 449 50 0.0392 0.0490 0.4400 4.4 1xzq:B
15 1nos:A 323 65 0.0392 0.0681 0.3385 4.6 2nos:A, 2oro:A, 2orp:A, 2orq:A
16 5zyr:A 306 128 0.0624 0.1144 0.2734 5.1 5zc2:B, 5zc2:A, 5zyr:B
17 3e65:B 421 67 0.0392 0.0523 0.3284 8.2 2bhj:A, 1df1:A, 1df1:B, 1dwv:A, 1dwv:B, 1dww:A, 1dww:B, 1dwx:A, 1dwx:B, 3dwj:A, 3dwj:B, 3e65:A, 3e67:A, 3e67:B, 3e68:A, 3e68:B, 3e6l:A, 3e6l:B, 3e6n:A, 3e6n:B, 3e6o:A, 3e6o:B, 3e6t:A, 3e6t:B, 3e7i:A, 3e7i:B, 3e7m:A, 3e7m:B, 3e7t:A, 3e7t:B, 3eai:A, 3eai:B, 3ebd:A, 3ebd:B, 3ebf:A, 3ebf:B, 4js9:A, 4js9:B, 1jwj:A, 1jwj:B, 1jwk:A, 1jwk:B, 1m8d:A, 1m8d:B, 1m8e:A, 1m8e:B, 1m8h:A, 1m8h:B, 1m8i:A, 1m8i:B, 1m9t:A, 1m9t:B, 1n2n:A, 1n2n:B, 1noc:A, 1nod:A, 1nod:B, 2nod:A, 2nod:B, 3nod:A, 3nod:B, 3nqs:A, 3nqs:B, 3nw2:A, 3nw2:B, 1qom:A, 1qom:B, 1qw4:A, 1qw4:B, 1qw5:A, 1qw5:B, 1r35:A, 1r35:B, 4ux6:B, 1vaf:A, 1vaf:B, 2y37:A, 2y37:B
18 4ub9:A 467 147 0.0731 0.0878 0.2789 8.7 4ub9:B, 4ub9:C, 4ub9:D, 4ub9:E, 4ub9:F, 4ub9:G, 4wgx:A
19 6yxx:EA 532 38 0.0250 0.0263 0.3684 8.9 7aoi:XL, 6yxy:EA
20 4w8j:A 1017 70 0.0446 0.0246 0.3571 9.6 4arx:A, 4arx:D, 4arx:B, 4arx:C, 4ary:A, 4ary:B, 4ary:C, 4ary:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218