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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MGSDLVLGLDIGIGSVGVGILNKVTGEIIHKNSRIFPAAQAENNLVRRTNRQGRRLARRKKHRRVRLNRLFEESGLITDF
TKISINLNPYQLRVKGLTDELSNEELFIALKNMVKHRGISYKTPGQIQLERYQTYGQLRGDFTVEKDGKKHRLINVFPTS
AYRSEALRILQTQQEFNPQITDEFINRYLEILTGKRKYYHGPGNEKSRTDYGRYRTSGETLDNIFGILIGKCTFYPDEFR
AAKASYTAQEFNLLNDLNNLTVPTETKKLSKEQKNQIINYVKNEKAMGPAKLFKYIAKLLDVADIKGYRIDKSGKAEIHT
FEAYRKMKTLETLDIEQMDRETLDKLAYVLTLNTEREGIQEALEHEFADGSFSQKQVDELVQFRKANSSIFGKGWHNFSV
KLMMELIPELYETSEEQMTILTRLGYIDEKLLTEEIYNPVVAKSVRQAIKIVNAAIKEYGDFDNIVIEMARETNEDDEKK
AIQKIQKANKDEKDAAMLKAANQYNGKAELPHSVFHGHKQLATKIRLWHQQGERCLYTGKTISIHDLINNSNQFEVDAIL
PLSITFDDSLANKVLVYATANQEKGQRTPYQALDSMDDAWSFRELKAFVRESKTLSNKKKEYLLTEEDISKFDVIERNLV
DTRYASRVVLNALQEHFRAHKIDTKVSVVRGQFTSQLRRHWGIEKTRDTYHHHAVDALIIAASSQLNLAPYQHFVDTLKS
KEFEDSILFSYQVDSKFNRKISDATIYATRQAKVGKDKADETYVLGKIKDIYTQDGYDAFMKIYKKDKSKFLMYRHDPQT
FEKVIEPILENYPNKVPCNPFLKYKEEHGYIRKYSKKGNGPEIKSLKYYDSKLGNHIDITPKDSNNKVVLQSVSPWRADV
YFNKTTGKYEILGLKYADLQFEKGTGTYKISQEKYNDIKKKEGVDSDSEFKFTLYKNDLLLVKDTETKEQQLFRFLSRTM
PKQKHYVELKPYDKQKFEGGEALIKVLGNVANSGQCKKGLGKSNISIYKVRTDVLGNQHIIKNEGDKPKLDF

The query sequence (length=1032) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6m0w:A 1032 1032 1.0000 1.0000 1.0000 0.0 6m0v:A, 6m0x:A
2 6rj9:C 836 492 0.4477 0.5526 0.9390 0.0 6rjd:C
3 6rj9:C 836 388 0.3391 0.4187 0.9021 0.0 6rjd:C
4 6rja:C 815 488 0.4399 0.5571 0.9303 0.0 6rja:F, 6rjg:C
5 6rja:C 815 387 0.3266 0.4135 0.8708 0.0 6rja:F, 6rjg:C
6 7vw3:A 1052 1028 0.3488 0.3422 0.3502 1.35e-157 5axw:A, 5czz:A, 7el1:A, 7eni:A, 7enr:A, 8jft:A, 8jg9:A, 8jg9:D
7 8hud:A 767 453 0.1996 0.2686 0.4547 5.46e-87
8 8hud:A 767 340 0.1143 0.1538 0.3471 4.28e-36
9 8hud:A 767 27 0.0155 0.0209 0.5926 2.9
10 8jtr:A 1056 1051 0.2849 0.2784 0.2797 1.49e-58
11 6jdv:A 1036 760 0.2054 0.2046 0.2789 6.33e-56 6kc8:A
12 8hnt:A 1000 741 0.1996 0.2060 0.2780 9.54e-55
13 6je4:O 1049 773 0.2035 0.2002 0.2717 2.13e-53 8hj4:A, 8ja0:A, 6je9:C
14 6jdq:A 1069 777 0.1986 0.1918 0.2638 6.14e-53 6je4:A, 6je4:E, 6je4:K, 6je9:A
15 8jtj:A 1042 1052 0.2800 0.2774 0.2747 2.25e-49
16 6kc7:A 963 275 0.0998 0.1070 0.3745 2.86e-41
17 6kc7:A 963 278 0.0717 0.0768 0.2662 6.38e-04
18 8uza:A 910 552 0.1434 0.1626 0.2681 1.45e-19 8uzb:A
19 8uza:A 910 348 0.0911 0.1033 0.2701 4.22e-13 8uzb:A
20 4oo8:A 1301 601 0.1473 0.1168 0.2529 3.55e-18 4zt0:C
21 5y36:A 1368 614 0.1531 0.1155 0.2573 4.08e-18 5f9r:B, 6ifo:A, 6ifo:B, 6mcb:A, 6mcc:A, 7s36:P, 7s38:P, 7s4x:A, 7v59:B, 7v59:E, 5vw1:A, 5vzl:A, 8ye6:A, 8ye9:A, 7z4c:B, 7z4e:B, 7z4k:B, 4zt0:A
22 7z4j:B 1345 613 0.1521 0.1167 0.2561 1.69e-17 6aeb:B, 6aeb:F, 6aeg:B, 6ai6:A, 5b2t:B, 5fw2:B, 5fw3:B, 8fzt:E, 6k4p:B, 6k4q:B, 8kah:B, 8kai:B, 8kaj:B, 8kak:B, 8kak:F, 8kal:B, 8kal:G, 8kam:B, 7ox7:B, 7ox8:B, 7ox9:B, 7oxa:B, 7qqo:B, 7qqp:B, 7qqq:B, 7qqr:B, 7qqs:B, 7qqt:B, 7qqu:B, 7qqv:B, 7qqx:B, 7qqz:B, 7qr0:B, 7qr1:B, 7qr5:B, 7qr7:B, 7qr8:B, 8wuv:A, 8ygj:A
23 8x5v:A 892 526 0.1395 0.1614 0.2738 1.70e-17
24 8x5v:A 892 419 0.1056 0.1222 0.2601 1.95e-09
25 6o0y:A 1146 611 0.1502 0.1353 0.2537 9.17e-17
26 8t7s:A 1312 613 0.1502 0.1181 0.2529 1.96e-16
27 8kag:B 1346 606 0.1463 0.1122 0.2492 2.76e-16 8kah:F, 8kai:F, 8kaj:F, 8spq:A, 8sqh:A, 8srs:A, 8tzz:A, 8u3y:A, 6vpc:B, 7z4h:B, 7z4i:B, 7z4l:B, 4zt9:A
28 5b2r:B 1319 608 0.1502 0.1175 0.2549 5.99e-16 5b2s:B, 5fq5:B, 5fw1:B, 8g1i:A, 6k3z:B, 6k4s:B, 6k4u:B, 6k57:B, 7qqw:B, 4un3:B, 4un4:B, 4un5:B, 8wus:A, 8wut:A, 8wuu:A
29 5xbl:A 1320 594 0.1463 0.1144 0.2542 6.09e-16
30 6je3:A 858 547 0.1231 0.1480 0.2322 1.93e-15
31 6jfu:A 884 603 0.1328 0.1550 0.2272 2.14e-15
32 6jfu:A 884 64 0.0203 0.0238 0.3281 0.64
33 8t6x:A 1278 607 0.1463 0.1182 0.2488 4.27e-14
34 8hnw:A 809 512 0.1124 0.1434 0.2266 2.81e-13
35 8hnw:A 809 377 0.0775 0.0989 0.2122 0.22
36 4cmq:B 1168 401 0.1066 0.0942 0.2743 3.15e-13 4cmp:B, 4cmq:A
37 7s37:P 1033 287 0.0756 0.0755 0.2718 1.14e-12 7s3h:P
38 5x2g:A 749 524 0.1269 0.1749 0.2500 7.48e-11 5x2h:A
39 5x2g:A 749 60 0.0233 0.0320 0.4000 1.73e-04 5x2h:A
40 5x2g:A 749 168 0.0368 0.0507 0.2262 1.2 5x2h:A
41 8hnv:A 745 498 0.1076 0.1490 0.2229 1.31e-10
42 8hnv:A 745 352 0.0775 0.1074 0.2273 1.28e-05
43 8wr4:B 1442 370 0.0814 0.0583 0.2270 1.33e-10
44 6o0z:A 1288 603 0.1463 0.1172 0.2504 3.81e-10
45 8d2k:A 1105 530 0.1172 0.1095 0.2283 2.45e-06 8d2l:A, 8d2n:A, 8d2p:A
46 4oge:A 977 514 0.1211 0.1279 0.2432 3.09e-05 4ogc:A
47 8d2q:A 906 301 0.0707 0.0806 0.2425 4.38e-05
48 7z4g:B 1188 375 0.0940 0.0816 0.2587 7.84e-05 7zo1:B
49 7s4v:A 1122 366 0.0901 0.0829 0.2541 8.51e-05 6o0x:A, 8t6p:A
50 4oo8:D 1163 362 0.0901 0.0800 0.2569 1.81e-04
51 7z4d:B 1259 361 0.0891 0.0731 0.2548 5.79e-04
52 8t6t:A 1168 372 0.0921 0.0813 0.2554 0.001 8t7s:G
53 8t76:A 1088 356 0.0853 0.0809 0.2472 0.012
54 8t6y:A 1148 356 0.0853 0.0767 0.2472 0.014 8t6o:A, 8t79:A
55 4zt9:C 1160 365 0.0872 0.0776 0.2466 0.033
56 8t77:A 1025 357 0.0862 0.0868 0.2493 0.075
57 6joo:A 834 54 0.0203 0.0252 0.3889 0.22
58 8pj9:A 1051 358 0.0736 0.0723 0.2123 0.24
59 7s4u:A 1092 360 0.0872 0.0824 0.2500 0.27
60 6wbr:A 942 81 0.0194 0.0212 0.2469 1.0 6wc0:A
61 8fmw:T 85 82 0.0252 0.3059 0.3171 1.1
62 7z4d:E 1166 160 0.0436 0.0386 0.2812 4.0
63 7nl1:D 400 85 0.0252 0.0650 0.3059 4.4 8bis:C, 8bis:A, 8biu:G, 8biu:A, 8biv:A, 8biv:E, 8biw:E, 8biw:A, 8bix:C, 8bix:A, 8biz:E, 8biz:A, 7nl1:A, 7nl1:B, 7nl1:C, 7nl1:E, 7nl1:F, 7nl1:G, 7nl1:H
64 7r30:B 102 56 0.0174 0.1765 0.3214 7.8 5o3q:A, 5o3q:C, 5o3q:B, 5o3r:A, 5o3r:B, 5o3r:C, 7obj:C, 7r2y:A, 7r2y:B, 7r2z:A, 7r2z:B, 7r2z:C, 7r30:A, 7r30:C, 7r32:A
65 6t6f:A 288 52 0.0174 0.0625 0.3462 9.5 8bfm:A, 8bfs:A, 2jc6:A, 2jc6:C, 6t28:AAA, 6t29:AAA, 6t6f:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218