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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MGEDQDLLKRAQGVFQPLPTVEEMQKIRPFTEEQVKLGHQLWYEPRLSKGNTVSCNSCHNLASAGVDNMPTSQGHKGQFG
GRNSPTALNAALLGSQFWDGRAADVEEQAGGPLVNPVEMANDSQEAAAAKIAKVPEYQEMFKKAFPEDGAVSFKNITTAL
GAFERTLLTPTKWDEYLKGNVNALSEQERKGVRAFMDNGCIACHNGVNLGGTTFQKFGLVQGPYWKFIEDPKRDKGRADV
TKKTEDEFFFRVPGLRNVAKTYPYFHNGSVWELDKAVTIMGKAQLGKDIPKEDVDNIVVFLNALSGNVSESARTMPELPL
TAPMESKPD

The query sequence (length=329) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6fu3:A 329 329 1.0000 1.0000 1.0000 0.0 6fu3:B, 6qkn:A, 6qkn:B, 7zs8:A, 7zs8:B
2 2vhd:A 323 326 0.4802 0.4892 0.4847 8.11e-104 1eb7:A, 2vhd:B
3 4aam:A 324 304 0.4407 0.4475 0.4770 1.45e-95 4aal:A, 4aal:B, 4aan:A, 4aao:B
4 1nml:A 316 325 0.4407 0.4589 0.4462 1.44e-94 1rz5:A, 1rz6:A
5 2c1v:A 335 311 0.4286 0.4209 0.4534 9.35e-93 2c1u:A, 2c1u:B, 2c1u:C, 2c1u:D, 2c1v:B
6 3hq6:A 324 325 0.4286 0.4352 0.4338 2.18e-92 3hq6:B, 3hq8:A, 3hq8:B, 3hq9:A, 3hq9:B
7 3o5c:A 308 302 0.4225 0.4513 0.4603 2.93e-86 3o5c:B, 3o5c:C, 3o5c:D
8 1iqc:A 308 288 0.3951 0.4221 0.4514 4.62e-85 1iqc:B, 1iqc:C, 1iqc:D
9 4aao:A 303 304 0.4225 0.4587 0.4572 1.02e-84
10 1zzh:B 308 325 0.4043 0.4318 0.4092 1.22e-81 1zzh:A, 1zzh:C, 1zzh:D
11 3hq7:A 304 325 0.3921 0.4243 0.3969 5.39e-78
12 6e1c:A 350 278 0.2736 0.2571 0.3237 9.29e-32
13 6e1c:B 323 271 0.2523 0.2570 0.3063 1.27e-26
14 4fa4:B 359 298 0.2888 0.2646 0.3188 4.51e-25 4fa1:A, 4fa1:B, 4fa4:A, 4fa5:A, 4fa5:B, 4fa9:A, 4fa9:B, 4fan:A, 4fan:B, 4fav:A, 4fav:B, 4fb1:A, 4fb1:B, 4k3i:A, 4k3i:B, 4l1q:A, 4l1q:B, 4l3g:A, 4l3g:B, 4l3h:A, 4l3h:B, 3l4m:A, 3l4m:B, 3l4o:A, 3l4o:B, 4o1q:A, 4o1q:B, 3orv:A, 3orv:B, 3pxs:A, 3pxs:B, 3pxt:A, 3pxt:B, 3pxw:A, 3pxw:B, 3rlm:A, 3rlm:B, 3rmz:A, 3rmz:B, 3rn0:A, 3rn0:B, 3rn1:A, 3rn1:B, 3sjl:A, 3sjl:B, 3sle:A, 3sle:B, 3svw:A, 3svw:B, 3sws:A, 3sws:B, 3sxt:A, 3sxt:B, 4y5r:A, 4y5r:B
15 6v59:A 419 368 0.3009 0.2363 0.2690 7.69e-19 6nx0:A, 6v59:B
16 6jlu:V 137 121 0.0942 0.2263 0.2562 0.82 8iwh:V, 8iwh:v, 6j3y:V, 6j3y:v, 6j3z:V, 6j3z:v, 6j40:V, 6j40:v, 8j5k:V, 8j5k:v, 6jlu:v, 7vd5:V, 7vd5:v
17 2b4k:A 617 67 0.0578 0.0308 0.2836 2.0 2b4k:B, 2b4k:D, 1nx9:A, 1nx9:B, 1nx9:C, 1nx9:D
18 5c2v:C 314 154 0.1064 0.1115 0.2273 4.2 5c2v:F, 5c2w:C, 5c2w:F
19 7zlt:C 415 109 0.0760 0.0602 0.2294 7.0 3ivy:A, 3iw0:A, 3iw1:A, 3iw2:A, 7qke:A, 7qnn:A, 7qwn:A, 7qwn:B, 7qwn:C, 7r1i:A, 7r1i:B, 7r1i:C, 7r3u:A, 7r3u:B, 7r3u:C, 2x5l:A, 2x5w:A, 2xc3:A, 2xn8:A, 7yxf:A, 7yxf:B, 7yxf:C, 7zgl:A, 7zgl:B, 7zgl:C, 7zic:A, 7zic:B, 7zic:C, 7zlt:A, 7zlt:B, 7zlz:A, 7zlz:B, 7zlz:C, 7zqr:A, 7zqr:B, 7zqr:C, 7zsu:A, 7zsu:B, 7zsu:C, 7zt0:A, 7zt0:B, 7zxd:A, 7zxd:B, 7zxd:C
20 3i5g:C 156 117 0.0912 0.1923 0.2564 7.3 3i5h:C, 3i5i:C
21 2cvz:C 289 95 0.0790 0.0900 0.2737 8.7 2cvz:A, 2cvz:B, 1wp4:A, 1wp4:B, 1wp4:C, 1wp4:D
22 7wfe:B5 206 25 0.0334 0.0534 0.4400 9.9 7wg5:B5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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