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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLDLADGRIPVIAGTGAN
ATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLH
NKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL

The query sequence (length=292) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5t25:A 293 292 1.0000 0.9966 1.0000 0.0 2ats:A, 2ats:B, 3i7s:A, 3i7s:B, 7jz8:A, 7jz8:B, 7jza:A, 7jza:B, 7jzb:A, 7jzb:B, 7jzg:A, 7jzg:B, 5t25:B, 1yxd:A, 1yxd:B
2 3puo:A 292 292 0.5719 0.5719 0.5719 7.85e-112 3puo:B, 3s8h:A, 3s8h:B
3 4dxv:A 291 291 0.5103 0.5120 0.5120 2.57e-103 3pue:B, 3pul:B, 3rk8:A, 3rk8:B, 3tak:A, 3tak:B, 3tce:A, 3tce:B, 3tdf:A, 3tdf:B, 3u8g:A, 3u8g:B
4 4pfm:A 295 289 0.5034 0.4983 0.5087 1.36e-101 4pfm:B
5 1o5k:A 295 296 0.4384 0.4339 0.4324 3.45e-84
6 4i7w:A 294 295 0.4486 0.4456 0.4441 2.65e-80 4i7w:B
7 5ktl:A 295 292 0.4144 0.4102 0.4144 8.49e-72 5ktl:B
8 7lvl:A 296 295 0.4212 0.4155 0.4169 1.36e-70 7lvl:B, 7lvl:C, 7lvl:E, 7lvl:D, 7lvl:F, 7mjf:A, 7mjf:B, 7mjf:C, 7mjf:D, 7mjf:E, 7mjf:F
9 7kkd:B 306 291 0.3767 0.3595 0.3780 5.99e-66 5f1u:A, 5f1u:B, 5f1u:C, 5f1u:D, 5f1v:A, 5f1v:C, 5f1v:B, 5f1v:D, 7kg2:A, 7kg2:C, 7kg2:B, 7kg2:D, 7kg2:E, 7kg2:F, 7kg5:A, 7kg5:B, 7kg5:C, 7kg5:E, 7kg5:F, 7kg9:A, 7kg9:E, 7kg9:B, 7kg9:C, 7kg9:D, 7kg9:F, 7kh4:A, 7kh4:F, 7kh4:B, 7kh4:C, 7kh4:D, 7kh4:E, 7kk1:A, 7kk1:B, 7kk1:C, 7kk1:D, 7kk1:E, 7kk1:F, 7kkd:A, 7kkd:F, 7kkd:E, 7kkd:C, 7kkd:D, 7kkg:A, 7kkg:D, 7kkg:B, 7kkg:E, 7kkg:C, 7kkg:F, 7kkt:A, 7kkt:F, 7kkt:B, 7kkt:E, 7kkt:C, 7kkt:D, 7kls:A, 7kls:F, 7kls:B, 7kls:C, 7kls:D, 7kls:E, 7klt:A, 7klt:C, 7klt:E, 7klt:F, 7kly:A, 7kly:D, 7kly:B, 7kly:C, 7kly:E, 7kly:F, 7km0:B, 7km0:C, 7km0:A, 7km0:D, 7km0:E, 7km0:F, 7km1:A, 7km1:B, 7km1:C, 7km1:D, 7km1:E, 7km1:F, 7kn9:A, 7kn9:B, 7kn9:C, 7kn9:D, 7kn9:E, 7kn9:F, 7knz:B, 7knz:C, 7knz:A, 7knz:D, 7knz:E, 7knz:F, 7ko3:A, 7ko3:B, 7ko3:C, 7ko3:D, 7ko3:E, 7ko3:F, 7kpc:A, 7kpc:B, 7kpc:C, 7kpc:D, 7kpc:E, 7kpc:F, 7kpe:B, 7kpe:C, 7kpe:A, 7kpe:D, 7kpe:E, 7kpe:F, 7kr7:A, 7kr7:E, 7kr7:B, 7kr7:C, 7kr7:D, 7kr7:F, 7kr8:B, 7kr8:D, 7kto:A, 7kto:B, 7kto:C, 7kto:D, 7kto:E, 7kto:F, 7ku6:D, 7kuz:A, 7kuz:F, 7kuz:B, 7kuz:C, 7kuz:D, 7kuz:E, 7kwf:B, 7kwf:F, 7kwf:A, 7kwf:C, 7kwf:D, 7kwf:E, 7kwn:B, 7kwp:A, 7kwp:B, 7kwp:C, 7kwp:D, 7kwp:E, 7kwp:F, 7kx1:A, 7kxg:A, 7kxg:C, 7kxg:B, 7kxg:D, 7kxg:E, 7kxg:F, 7kxh:A, 7kxh:D, 7kxh:B, 7kxh:C, 7kxh:E, 7kxh:F, 7kz2:A, 7kz2:D, 7kz2:B, 7kz2:C, 7kz2:E, 7kz2:F, 7lcf:A, 7lcf:B, 7lcf:F, 7lcf:C, 7lcf:D, 7lcf:I, 7lcf:E, 7lcf:G, 7lcf:H, 7lcf:J, 7lcf:K, 7lcf:L, 7m06:B, 7m06:C, 7m06:D, 4m19:A, 4m19:B, 4m19:C, 4m19:D, 4mlr:A, 4mlr:D, 4mlr:C, 4mlr:E, 4mlr:F, 4mlr:G, 4mlr:H, 6u01:B
10 4fha:A 307 283 0.3801 0.3616 0.3922 2.98e-64 4fha:B
11 5ud6:C 299 297 0.4212 0.4114 0.4141 8.25e-63 5ud6:A, 5ud6:B, 5ud6:D
12 3di1:B 291 290 0.3596 0.3608 0.3621 1.29e-53 3di1:A
13 6vvh:BBB 313 286 0.3527 0.3291 0.3601 2.03e-46 4dpq:A, 4dpq:B, 7mds:A, 7mds:B, 6vvh:AAA, 6vvh:CCC, 6vvh:DDD
14 4hnn:F 320 286 0.3356 0.3063 0.3427 4.93e-44 4hnn:A, 4hnn:B, 4hnn:C, 4hnn:D, 4hnn:E, 4hnn:G, 4hnn:H
15 5j5d:A 297 238 0.2979 0.2929 0.3655 3.42e-43 3l21:B, 1xxx:A, 1xxx:B, 1xxx:C, 1xxx:D, 1xxx:E, 1xxx:F, 1xxx:G, 1xxx:H
16 5ui3:C 306 276 0.3116 0.2974 0.3297 3.21e-38 5ui3:D, 5ui3:A, 5ui3:B
17 3nev:A 298 241 0.2568 0.2517 0.3112 4.95e-33 3nev:B, 3nev:C, 3nev:D, 4oe7:A, 4oe7:B, 4oe7:C, 4oe7:D, 4onv:A, 4onv:B, 4onv:C, 4onv:D, 4ptn:A, 4ptn:B, 4ptn:C, 4ptn:D, 4u4m:A, 4u4m:B, 4u4m:C, 4u4m:D
18 5c55:A 307 298 0.2842 0.2704 0.2785 1.68e-30 5c55:B
19 8u8w:A 297 282 0.2500 0.2458 0.2589 1.26e-27
20 3na8:A 291 286 0.2500 0.2509 0.2552 3.35e-25 3na8:B, 3na8:C, 3na8:D
21 2wpb:A 302 241 0.2329 0.2252 0.2822 1.14e-24 4bwl:A, 4bwl:B, 4bwl:C, 4bwl:D, 1fdy:A, 1fdy:B, 1fdy:C, 1fdy:D, 1fdz:A, 1fdz:B, 1fdz:C, 1fdz:D, 1hl2:A, 1hl2:B, 1hl2:C, 1hl2:D, 3lbc:D, 3lcw:A, 3lcw:B, 3lcw:C, 3lcw:D, 4uui:A, 4uui:B, 4uui:C, 4uui:D, 2wkj:C, 2wkj:D, 2wpb:B, 2wpb:C, 2wpb:D, 2xfw:A, 2xfw:B, 2xfw:C, 2xfw:D
22 4woq:C 290 275 0.2295 0.2310 0.2436 4.00e-18 4woq:D, 4woq:E, 4woq:F, 4woq:H, 4woz:B, 4woz:F
23 1f74:A 293 233 0.2055 0.2048 0.2575 3.15e-17 1f73:A, 1f73:B, 1f73:C, 1f73:D, 1f74:C, 1f7b:A, 1f7b:C
24 4img:A 293 285 0.2397 0.2389 0.2456 3.61e-17 4imf:A, 4imf:B, 4img:B
25 6rb7:A 305 294 0.2192 0.2098 0.2177 1.52e-16 6rb7:B, 6rb7:E, 6rb7:F, 6rd1:A, 6rd1:B
26 5kzd:A 284 227 0.1952 0.2007 0.2511 1.04e-12 5kzd:B, 5kzd:C, 5kzd:D
27 3qfe:A 305 246 0.2021 0.1934 0.2398 1.43e-12
28 5hwn:B 310 178 0.1644 0.1548 0.2697 1.47e-12 5hwm:A, 5hwm:B, 5hwm:C, 5hwm:D, 5hwn:A, 5hwn:C, 5hwn:D, 4ur8:A, 4ur8:B, 4ur8:C, 4ur8:D
29 6g3z:A 293 240 0.2123 0.2116 0.2583 2.02e-12 6g3z:B, 6gt8:A, 6gt8:B, 6gv2:A, 6gv2:B, 6h2s:A, 6h2s:B, 6h2s:C, 6h2s:D, 6h7s:A, 6h7s:B, 1w3i:A, 1w3i:B, 1w3i:C, 1w3i:D, 1w3n:A, 1w3n:B, 1w3n:C, 1w3n:D, 1w3t:A, 1w3t:B, 1w3t:C, 1w3t:D
30 2hmc:A 314 256 0.2568 0.2389 0.2930 1.10e-11
31 2nuy:A 288 239 0.2021 0.2049 0.2469 1.13e-09 2nuy:B
32 8do5:B 324 137 0.1233 0.1111 0.2628 1.71e-08 8do5:A
33 2r94:A 286 202 0.1575 0.1608 0.2277 5.06e-06 2r94:D, 2r94:B, 2r94:C
34 2chq:A 313 64 0.0616 0.0575 0.2812 1.7 2chg:A, 2chg:B, 2chg:C, 2chg:D, 2chq:B, 2chq:C
35 7a0r:J 136 51 0.0411 0.0882 0.2353 2.8 7a0s:J, 7a18:J, 3cf5:J, 3dll:J, 5dm6:J, 5dm7:J, 4io9:J, 4ioa:J, 4ioc:J, 5jvg:J, 5jvh:J, 1nkw:K, 3pio:J, 3pip:J, 4u67:J, 4v4g:BN, 4v4g:DN, 4v4g:FN, 4v4g:HN, 4v4g:JN, 4wfn:J, 1y69:K, 2zjp:J, 2zjq:J, 2zjr:J
36 3s27:H 797 61 0.0616 0.0226 0.2951 2.9 3s27:A, 3s27:B, 3s27:C, 3s27:D, 3s27:E, 3s27:F, 3s27:G, 3s28:A, 3s28:B, 3s28:C, 3s28:D, 3s28:E, 3s28:F, 3s28:G, 3s28:H, 3s29:A, 3s29:B, 3s29:C, 3s29:D, 3s29:E, 3s29:F, 3s29:G, 3s29:H
37 6k21:A 173 42 0.0548 0.0925 0.3810 3.2 6k27:A, 6k27:B, 6k27:C, 6k27:D, 6k27:E, 6k27:F, 6k27:G, 6k27:H, 6ki8:A, 6ki8:B, 6ki8:C
38 7mqa:SC 229 118 0.1164 0.1485 0.2881 4.3 2ipx:A, 7se7:A, 7se8:A, 7se8:B, 7se9:A, 7se9:B, 7sea:A, 7seb:A, 7sec:A, 7sec:B, 7sed:A
39 6xiv:A 257 42 0.0445 0.0506 0.3095 7.9 6xiu:A, 6xiu:B, 6xiv:B
40 2v5k:A 260 54 0.0651 0.0731 0.3519 8.1 4b5s:A, 4b5s:B, 4b5t:A, 4b5t:B, 4b5u:A, 4b5u:B, 4b5v:A, 4b5v:B, 4b5w:A, 4b5w:B, 4b5w:C, 4b5w:D, 4b5w:E, 4b5w:F, 2v5k:B
41 7u7h:A 423 159 0.1336 0.0922 0.2453 9.0 7u7h:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218