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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MFSWMKKAIRTVTSSLKELYRTKLLPLEEHYRFGSFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVG
PEPTTDCFVAVMHGETEGTVPGNALNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGSRGYDFPAVLRWFAERVDLI
ILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVP
DNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPTVFGKENKKKQLILKLPVIFAKIQLE
HHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDDMLAQDIAKLMPLLRQEELESVEAGVAGGAFEGTRMGPFVDA
EWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGL
PTNLPRRLVPPSKRRQK

The query sequence (length=497) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4cid:A 497 497 1.0000 1.0000 1.0000 0.0 2qpt:A
2 5mtv:A 379 377 0.5433 0.7124 0.7162 0.0 5mvf:A
3 2jq6:A 139 126 0.1569 0.5612 0.6190 1.32e-46 2kff:A, 2kfg:A, 2kfh:A, 2ksp:A
4 1eh2:A 95 94 0.1006 0.5263 0.5319 3.22e-26 1f8h:A, 1ff1:A, 2jxc:A
5 3fia:A 98 94 0.0684 0.3469 0.3617 2.93e-17
6 1fi6:A 92 91 0.0724 0.3913 0.3956 3.09e-13
7 6yet:A 104 84 0.0644 0.3077 0.3810 1.40e-12
8 1c07:A 95 94 0.0785 0.4105 0.4149 3.18e-12
9 1iq3:A 110 96 0.0765 0.3455 0.3958 6.09e-11
10 6yeu:A 107 44 0.0362 0.1682 0.4091 1.98e-04 6yig:A
11 8t3k:C 541 44 0.0362 0.0333 0.4091 0.88
12 6j72:A 561 49 0.0342 0.0303 0.3469 0.90
13 9em9:A 512 49 0.0322 0.0312 0.3265 1.1 9em9:B
14 8i9w:CL 397 66 0.0382 0.0479 0.2879 1.6 8i9t:CL, 8i9v:CL, 8i9x:CL, 8i9y:CL, 8i9z:CL, 8ia0:CL, 8pv1:CL, 8pv2:CL, 8pv3:CL, 8pv4:CL, 8pv5:CL, 8pv6:CL, 8pv7:CL, 8pv8:CL, 8pvk:CL, 8pvl:CL
15 6m7y:A 952 53 0.0322 0.0168 0.3019 2.2 6m7y:B
16 7p2f:A 329 86 0.0423 0.0638 0.2442 3.0 7p2f:B, 7p2f:C
17 8igq:A 227 48 0.0322 0.0705 0.3333 3.3 8idd:B, 8idd:A, 8igq:B, 8jia:A, 8jia:B
18 6vij:B 191 49 0.0362 0.0942 0.3673 3.9 6vii:B, 6vii:A, 6vij:A, 6vik:B
19 2aao:A 147 91 0.0543 0.1837 0.2967 5.2 2aao:B
20 1m8v:A 72 60 0.0382 0.2639 0.3167 5.8 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
21 5fhd:B 400 26 0.0221 0.0275 0.4231 8.5
22 8cas:k 579 123 0.0543 0.0466 0.2195 8.5 5ll6:h, 6zce:k, 6zu9:k
23 5ftc:A 431 26 0.0221 0.0255 0.4231 8.6 5fhd:A, 5fhe:A, 5fhf:A, 5ftb:A, 5fte:A, 5ftf:A, 6l3g:A, 6l3g:B
24 8ujg:A 530 57 0.0342 0.0321 0.2982 8.8 8uhz:A, 8ui1:A, 8ui6:A, 8uje:A, 8ujf:A, 8ujf:B, 8ujg:B, 8ujh:A
25 7syv:x 627 149 0.0785 0.0622 0.2617 9.2 8pj3:0, 8pj4:0, 8pj5:0, 7syw:x, 7syx:x, 7tql:1, 4ujc:AB, 4ujd:BB
26 8aht:A 140 46 0.0302 0.1071 0.3261 9.4 8aht:B
27 6iih:A 446 30 0.0241 0.0269 0.4000 9.4 6iih:B, 6lb7:B, 6xqo:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218