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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MEYIIKNGFVYCPLNGVDGEKMDICVKDGKIVESVSDSAKVIDASGKIVMPGGVDPHSHIAGAKVNVGRMYRPEDSKRDA
EKFKGGRAGSGFSVPSTFMTGYRYAQMGYTTAMEAAMPPLLARHTHEEFHDTPIIDHAAYPLFGNNWFVMEYLKEGDVDA
CAAYASWLLRATKGYTIKIVNPAGTEAWGWGGNVHGIYDPAPYFDITPAEIIKGLAEVNEKLQLPHSIHLHCNDLGHPGN
YETTLASFDVPKNIKPNPATGSRDTVLYATHVQFHSYGGTTWRDFVSEAPKIADYVNKNDHIVIDVGQITLDETTTMTAD
GPMEYDLHSLNGLKWANCDVELETGSGVVPFIYSARAPVPAVQWAIGMELFLLIDNPEKVCLTTDSPNAGPFTRYPRVIA
WLMSNKYRMNLIEGELHKWAQRKSTVATIDREYTFSEIAQITRATSAKVLGLSDTKGHLGVGADADIAVYDINPETVDPS
AEYMAIEEAFSRAACVLKDGEIVVKDGEVVASPHGRTYWVDTQVDESIYSEVLANVESKFKQYYSVNFANYPVQDDYLPK
SAPVKGVML

The query sequence (length=569) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5t5i:A 569 569 1.0000 1.0000 1.0000 0.0 5t5i:I, 5t5m:A, 5t61:A, 5t61:G, 5t61:M, 5t61:S, 5t61:Y, 5t61:e, 5t61:k, 5t61:q
2 7bkb:G 568 565 0.5360 0.5370 0.5398 0.0 7bkb:g, 7bkc:G, 7bkc:g
3 6s6y:A 548 569 0.3480 0.3613 0.3480 1.91e-93 6s6y:E, 6s6y:I, 6s6y:M
4 1nfg:A 457 69 0.0439 0.0547 0.3623 1.12e-05 1nfg:B, 1nfg:C, 1nfg:D
5 1nfg:A 457 91 0.0439 0.0547 0.2747 0.036 1nfg:B, 1nfg:C, 1nfg:D
6 4tqt:D 481 43 0.0404 0.0478 0.5349 2.27e-05 4tqt:A, 4tqt:B, 4tqt:C, 4tqt:E, 4tqt:F
7 4tqt:D 481 88 0.0475 0.0561 0.3068 0.15 4tqt:A, 4tqt:B, 4tqt:C, 4tqt:E, 4tqt:F
8 1gkr:A 451 65 0.0527 0.0665 0.4615 4.57e-05 1gkr:B, 1gkr:C, 1gkr:D
9 4bjh:A 422 64 0.0457 0.0616 0.4062 4.58e-05 3d6n:A
10 6gdd:A 375 64 0.0457 0.0693 0.4062 5.71e-05 6gde:A, 6gdf:A, 1xrf:A, 1xrt:A, 1xrt:B
11 1k1d:A 460 64 0.0457 0.0565 0.4062 9.03e-05 1k1d:B, 1k1d:C, 1k1d:D, 1k1d:E, 1k1d:F, 1k1d:G, 1k1d:H
12 1k1d:A 460 88 0.0527 0.0652 0.3409 2.13e-04 1k1d:B, 1k1d:C, 1k1d:D, 1k1d:E, 1k1d:F, 1k1d:G, 1k1d:H
13 8hfd:A 452 64 0.0475 0.0597 0.4219 1.57e-04 3e74:B, 8hfd:B, 8hfd:C, 8hfd:D
14 3e74:A 429 64 0.0475 0.0629 0.4219 2.10e-04 3e74:C, 3e74:D
15 3dc8:A 483 42 0.0351 0.0414 0.4762 4.80e-04 3dc8:B
16 3dc8:A 483 89 0.0404 0.0476 0.2584 0.26 3dc8:B
17 3sfw:A 461 64 0.0422 0.0521 0.3750 6.47e-04 3sfw:B
18 3sfw:A 461 86 0.0439 0.0542 0.2907 0.037 3sfw:B
19 4kir:A 460 101 0.0475 0.0587 0.2673 6.93e-04 4kir:B, 4kqn:A, 4kqn:B, 1yny:A, 1yny:B
20 4kir:A 460 60 0.0334 0.0413 0.3167 0.087 4kir:B, 4kqn:A, 4kqn:B, 1yny:A, 1yny:B
21 4gz7:A 492 43 0.0334 0.0386 0.4419 0.002 4h00:A, 4h01:A, 4lcq:A, 4lcr:A, 4lcs:A
22 4gz7:A 492 101 0.0404 0.0467 0.2277 2.9 4h00:A, 4h01:A, 4lcq:A, 4lcr:A, 4lcs:A
23 3mpg:A 426 64 0.0422 0.0563 0.3750 0.002 3mpg:B, 4yiw:A, 4yiw:B
24 1gkp:A 458 74 0.0457 0.0568 0.3514 0.003 1gkp:B, 1gkp:C, 1gkp:D, 1gkp:E, 1gkp:F, 1gkq:A, 1gkq:B, 1gkq:C, 1gkq:D
25 1gkp:A 458 21 0.0246 0.0306 0.6667 0.16 1gkp:B, 1gkp:C, 1gkp:D, 1gkp:E, 1gkp:F, 1gkq:A, 1gkq:B, 1gkq:C, 1gkq:D
26 2vr2:A 478 59 0.0387 0.0460 0.3729 0.006
27 2vr2:A 478 36 0.0228 0.0272 0.3611 1.0
28 3mkv:A 414 74 0.0439 0.0604 0.3378 0.006 3mkv:B, 3mkv:C, 3mkv:D, 3mkv:E, 3mkv:F, 3mkv:G, 3mkv:H
29 3mkv:A 414 78 0.0457 0.0628 0.3333 0.28 3mkv:B, 3mkv:C, 3mkv:D, 3mkv:E, 3mkv:F, 3mkv:G, 3mkv:H
30 2vhl:B 393 50 0.0351 0.0509 0.4000 0.015 2vhl:A
31 4cns:D 479 90 0.0439 0.0522 0.2778 0.021 4cns:A, 4cns:B, 4cns:C
32 4cns:D 479 43 0.0299 0.0355 0.3953 0.093 4cns:A, 4cns:B, 4cns:C
33 2fty:A 532 64 0.0422 0.0451 0.3750 0.023 2fty:B, 2fty:C, 2fty:D, 2fvk:A, 2fvk:B, 2fvk:C, 2fvk:D, 2fvm:A, 2fvm:B, 2fvm:C, 2fvm:D
34 4v1x:E 474 44 0.0351 0.0422 0.4545 0.025 4v1x:A, 4v1x:B, 4v1x:C, 4v1x:D, 4v1x:F, 4v1y:A, 4v1y:B, 4v1y:C, 4v1y:D, 4v1y:E, 4v1y:F, 4v1y:G, 4v1y:H, 4v1y:I, 4v1y:J, 4v1y:K, 4v1y:L
35 2ftw:A 484 62 0.0404 0.0475 0.3710 0.029
36 2ftw:A 484 57 0.0246 0.0289 0.2456 1.4
37 3n2c:A 408 71 0.0422 0.0588 0.3380 0.040 3feq:A, 3feq:B, 3feq:C, 3feq:D, 3feq:E, 3feq:F, 3feq:G, 3feq:H, 3feq:I, 3feq:J, 3feq:K, 3feq:L, 3feq:M, 3feq:N, 3feq:O, 3feq:P, 3n2c:B, 3n2c:C, 3n2c:D, 3n2c:E, 3n2c:F, 3n2c:G, 3n2c:H, 3n2c:I, 3n2c:J, 3n2c:K, 3n2c:L, 3n2c:M, 3n2c:N, 3n2c:O, 3n2c:P
38 4b92:A 476 64 0.0387 0.0462 0.3438 0.076 4b92:B
39 4b92:A 476 31 0.0246 0.0294 0.4516 5.5 4b92:B
40 3gri:B 423 63 0.0404 0.0544 0.3651 0.077 3gri:A
41 1onx:A 389 60 0.0369 0.0540 0.3500 0.080 2aqo:A, 2aqo:B, 2aqv:A, 2aqv:B, 1onw:A, 1onw:B, 1onx:B, 1po9:A, 1po9:B, 1poj:A, 1poj:B, 1pok:B, 1pok:A, 1ybq:A, 1ybq:B
42 1onx:A 389 83 0.0457 0.0668 0.3133 0.54 2aqo:A, 2aqo:B, 2aqv:A, 2aqv:B, 1onw:A, 1onw:B, 1onx:B, 1po9:A, 1po9:B, 1poj:A, 1poj:B, 1pok:B, 1pok:A, 1ybq:A, 1ybq:B
43 8je0:A 378 38 0.0299 0.0450 0.4474 0.084 8je0:B, 8je0:C, 8je0:D
44 1m7j:A 474 63 0.0369 0.0443 0.3333 0.091 1rjp:A, 1rjq:A, 1rjr:A, 1rk5:A, 1rk6:A, 1v4y:A, 1v51:A
45 5e5c:C 479 46 0.0228 0.0271 0.2826 0.16 6ajd:A, 6ajd:B, 7e3u:A, 7e3u:B, 5e5c:A, 6klk:A, 6klk:B, 8wq9:A, 8wq9:B, 5ykd:A, 5ykd:B, 5ykd:C, 5ykd:D
46 5e5c:C 479 38 0.0246 0.0292 0.3684 1.3 6ajd:A, 6ajd:B, 7e3u:A, 7e3u:B, 5e5c:A, 6klk:A, 6klk:B, 8wq9:A, 8wq9:B, 5ykd:A, 5ykd:B, 5ykd:C, 5ykd:D
47 2g3f:A 414 31 0.0246 0.0338 0.4516 0.16 2bb0:A, 2bb0:B, 2g3f:B
48 4cqb:A 402 74 0.0422 0.0597 0.3243 0.26 5akq:A, 5akq:B, 4cqb:B, 4cqc:A, 4cqc:B, 4cqd:A, 4cqd:B, 2qt3:A, 2qt3:B
49 4cqb:A 402 41 0.0281 0.0398 0.3902 9.4 5akq:A, 5akq:B, 4cqb:B, 4cqc:A, 4cqc:B, 4cqd:A, 4cqd:B, 2qt3:A, 2qt3:B
50 3gip:A 474 63 0.0351 0.0422 0.3175 0.37 3gip:B, 3giq:A, 3giq:B
51 3lnp:A 441 85 0.0404 0.0522 0.2706 0.40
52 8dqn:C 388 71 0.0404 0.0593 0.3239 0.66 8dqn:A, 8dqn:B, 8dqn:D, 8dqn:E, 8dqn:F, 8dqn:G, 8dqn:H
53 5xgx:A 381 74 0.0404 0.0604 0.3108 0.81 5xgw:A, 5xgw:B, 5xgx:B
54 3hm7:B 437 43 0.0264 0.0343 0.3488 0.97 3hm7:A, 3hm7:C, 3hm7:D, 3hm7:E, 3hm7:F
55 3nqb:A 587 33 0.0264 0.0256 0.4545 1.2 3nqb:B, 3t81:A, 3t81:B
56 1a5o:C 566 54 0.0351 0.0353 0.3704 1.3 1a5n:C, 1ef2:A, 1ejr:C, 1ejs:C, 1ejt:C, 1eju:C, 1ejv:C, 1fwa:C, 1fwb:C, 1fwc:C, 1fwd:C, 1fwe:C, 1fwf:C, 1fwg:C, 1fwh:C, 1fwi:C, 1fwj:C, 2kau:C, 1krb:C, 1krc:C
57 8a18:CCC 570 56 0.0387 0.0386 0.3929 2.2 5a6t:C, 4ac7:C, 7b58:CCC, 7b59:CCC, 7b5a:CCC, 4ceu:C, 4cex:C, 5fsd:C, 5fse:C, 6g48:C, 6h8j:C, 6i9y:C, 1ie7:C, 5ol4:C, 7p7n:CCC, 7p7o:CCC, 8q2e:C, 6qdy:C, 6rkg:C, 6rp1:C, 1s3t:C, 1ubp:C, 2ubp:C, 3ubp:C, 4ubp:C, 7zcy:C
58 2z00:A 426 39 0.0228 0.0305 0.3333 3.6
59 2vun:A 385 46 0.0334 0.0494 0.4130 3.6 2vun:B, 2vun:C, 2vun:D
60 6ohb:A 435 45 0.0246 0.0322 0.3111 3.7 6ohb:B, 6ohb:C, 6ohb:D, 6ohc:A, 6ohc:B, 6ohc:C, 6ohc:D
61 3be7:A 398 45 0.0299 0.0427 0.3778 4.3 3be7:E, 3be7:B, 3be7:D, 3be7:C, 3be7:F, 3be7:G, 3be7:H, 3dug:A, 3dug:B, 3dug:C, 3dug:D, 3dug:E, 3dug:F, 3dug:G, 3dug:H
62 2paj:A 421 60 0.0369 0.0499 0.3500 4.5
63 7nut:A 401 41 0.0299 0.0424 0.4146 5.1 7nut:B, 7nuu:A, 7nuu:B
64 7cf6:A 384 22 0.0176 0.0260 0.4545 6.0 7cdh:X, 7cf6:B, 7cf6:C, 7cf6:D
65 8ihq:A 399 37 0.0246 0.0351 0.3784 7.2 8ihq:B, 8ihq:C, 8ihq:D, 8ihq:E, 8ihq:F, 8ihq:G, 8ihq:H, 8ihr:A, 8ihr:B, 8ihr:C, 8ihr:D, 8ihr:E, 8ihr:F, 8ihr:G, 8ihr:H, 8ihs:A, 8ihs:B, 8ihs:C, 8ihs:D, 8ihs:E, 8ihs:F, 8ihs:G, 8ihs:H, 8j85:A, 8j85:B, 8j85:C, 8j85:D, 8j85:E, 8j85:F, 8j85:G, 8j85:H
66 8ouo:A 648 53 0.0299 0.0262 0.3208 8.5
67 5hmd:A 456 46 0.0281 0.0351 0.3478 8.6 5hmd:B, 5hme:A, 5hme:B, 5hmf:A, 5hmf:B, 4lh8:A, 4lh8:B, 3ls9:A, 3ls9:B, 3lsb:A, 3lsb:B, 3lsc:A, 3lsc:B
68 8ouo:B 625 53 0.0299 0.0272 0.3208 9.4 6nq0:A, 6nq0:B, 6nq2:A, 6nq2:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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