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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MEYHVAKTGSDEGKGTLKDPFLTINKAASVAMAGDTIIVHEGVYREWVKPKYKGLSDKRRITYKAAEGEKVVIKGSERIQ
SWQRVEGNVWRCQLPNSFFGEFNPYKEEVFGDWLLTVNEKKHLGDVYLNGMSFYEVTNYEDLFNPQLRTEVLDHWTQKIV
PIKNAEQTKYVWYAEVDREKTTIYANFQGADPNEEFVEINVRRSCFYPVETGIDYITVKGFEMAHAATPWAPPTADQPGL
IGPNWSKGWIIEDNIIHDAKCSAISIGKEATTGNNYRSIRKDKPGYQYQLEAVFNAKRNGWSKEKIGSHIIRNNTIYDCG
QNAIVGHLGGVFSEIYNNHIYNIALKREFYGHEIAGIKLHAAIDVQIHHNRIHDCSLGLWLDWEAQGTRVSKNLFYNNNR
DVFVEVSHGPYLVDHNILSSEYAIDNMSQGGAYINNLIAGKMNQRKVLNRSTQYHLPHSTEVAGFAFVYGGDDRFYNNIF
IGKEGLENVGTSHYNNCTTSLEEYIEKVNEVPGDLGEFERVEQPVYINKNAYFNGAEPFEKEKDNLVKKDFDPKLAIIDE
GDEVYLSLQLPDEFENIVGDIHSTKTLERVRIVDAEYESPDGKELVLDTDYLDAKKPENSSIGPIALLKKGNNYIKVW

The query sequence (length=638) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3vsu:A 638 638 1.0000 1.0000 1.0000 0.0 3vsu:B, 3vsu:C, 3vsu:D, 3vsv:A, 3vsv:B, 3vsv:D, 3vsv:C
2 5mqp:E 602 112 0.0439 0.0465 0.2500 0.040 5mqp:A, 5mqp:B, 5mqp:C, 5mqp:D, 5mqp:F, 5mqp:G, 5mqp:H
3 5olq:C 427 42 0.0251 0.0375 0.3810 0.096 5olq:A, 5olq:B, 5olr:A, 5olr:B, 5olr:C, 5ols:A
4 4uss:A 306 221 0.0846 0.1765 0.2443 0.84
5 7k66:A 1265 81 0.0376 0.0190 0.2963 1.6 1d7p:M, 3hnb:M, 7kbt:A, 6mf0:A, 6mf0:B, 4xzu:M
6 6lrg:B 681 92 0.0376 0.0352 0.2609 1.9 6lrg:A, 6lrh:A, 6lrh:B
7 4azc:B 421 82 0.0376 0.0570 0.2927 2.0 4azc:A, 4azc:C, 4azc:D, 4azg:A, 4azg:B, 4azh:A, 4azh:B, 4azh:C, 4azh:D, 4azi:A, 4azi:B, 2yl5:A, 2yl5:C, 2yl9:C, 2yla:B, 2yla:C
8 4f48:B 97 79 0.0392 0.2577 0.3165 2.7
9 5zku:F 443 62 0.0298 0.0429 0.3065 3.9 5zku:A, 5zku:B, 5zku:C, 5zku:D, 5zku:E, 5zkw:A, 5zkw:B, 5zkw:C, 5zkw:E, 5zkw:F, 5zl4:A, 5zla:A, 5zla:D, 5zla:B, 5zla:C, 5zla:F, 5zla:E
10 8pjb:A 962 35 0.0188 0.0125 0.3429 6.2 8b9g:A, 8b9k:A, 8pjj:A
11 1xjq:B 590 21 0.0188 0.0203 0.5714 6.4 8i1m:A, 2ofw:A, 2ofw:B, 2ofw:C, 2ofw:D, 2ofw:E, 2ofw:F, 2ofw:G, 2ofw:H, 2ofx:A, 2ofx:B, 2pey:A, 2pez:A, 2pez:B, 2qjf:A, 2qjf:B, 1x6v:B, 1xnj:B
12 8cdu:C 708 48 0.0235 0.0212 0.3125 6.9 8cec:C, 8ced:C, 8cee:C
13 2pyh:B 377 123 0.0517 0.0875 0.2683 7.6 2pyg:A, 2pyg:B, 2pyh:A
14 4fnm:A 569 132 0.0502 0.0562 0.2424 9.2 5ch5:A, 5ivi:A, 5ivk:A, 4qwm:A, 5tyj:A, 5tyk:A, 5tyl:A, 5tym:A, 5tyn:A, 5tyo:A, 5typ:A, 4ubi:A, 4ubj:A, 4ubk:A, 4ubl:A, 4ubm:A, 4ubn:A, 4ubo:A, 4w1p:A, 4w1q:A, 4w1r:A, 4w1s:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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