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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MEWIHEKSPKHNSYDIIEKRYNEEFKMTYTVYQHKKAKTQVISLGTNDPLDVEQAFAFYVKTLTHSGKGIPHILEHSVLS
GSKNYNYKNSIGLLEKGTLHTHLNAYTFNDRTVYMAGSMNNKDFFNIMGVYMDSVFQPNVLENKYIFETEGWTYEVEKLK
EDEKGKAEIPQMKDYKVSFNGIVYNEMKGALSSPLEDLYHEEMKYMFPDNVHSNNSGGDPKEITNLTYEEFKEFYYKNYN
PKKVKVFFFSKNNPTELLNFVDQYLGQLDYSKYRDDAVESVEYQTYKKGPFYIKKKYGDHSEEKENLVSVAWLLNPKVSD
LSLENPTDYFVLLIINNLLIHTPESVLYKALTDCGLGNNVIDRGLNDSLVQYIFSIGLKGIKRNNEKIKNFDKVHYEVED
VIMNALKKVVKEGFNKSAVEASINNIEFILKEANLKTSKSIDFVFEMTSKLNYNRDPLLIFEFEKYLNIVKNKIKNEPMY
LEKFVEKHFINNAHRSVILLEGDENYAQEQENLEKQELKKRIENFNEQEKEQVIKNFEELSKYKNAEESPEHLNKFPIIS
ISDLNKKTLEVPVNVYFTNINENNNIMETYNKLKTNEHMLKDNMDVFLKKYVLKKYEGNVPILVYEMPTTGIVYLQFVFS
LDHLTVDELAYLNLFKTLILENKTNKRSSEDFVILREKNIGSMSANVALYSKDDHLNVTDKYNAQALFNLEMHVLSHKCN
DALNIALEAVKESDFSNKKKVIDILKRKINGMKTTFSEKGYAILMKYVKAHLNSKHYAHNIIYGYENYLKLQEQLELAEN
DFKTLENILVRIRNKIFNKKNLMVSVTSDYGALKHLFVNSNESLKNLVSYFEENDKYIVMGWNEEIKSKKLFDEEKVKKE
FFVLPTFVNSVSMSGILFKPGEYLDPSFTVIVAALKNSYLWDTVRGLNGAYGVFADIEYDGSVVFLSARDPNLEKTLATF
RESAKGLRKMADTMTENDLLRYIINTIGTIDKPRRGIELSKLSFLRLISNESEQDRVEFRKRIMNTKKEDFYKFADLLES
KVNEFEKNIVIITTKEKANEYIANVDGEFKKVLIE

The query sequence (length=1075) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7dia:A 1072 1074 0.9972 1.0000 0.9981 0.0 3s5k:A, 8wyt:A, 8wyx:A, 8wyy:A
2 3s5m:A 1094 1092 0.9991 0.9817 0.9835 0.0 7di7:A, 7dij:A, 8ho4:A, 8ho5:A, 3s5h:A, 7vpe:A, 8wxw:A, 8wxz:A, 8wyu:A
3 2fge:A 979 1035 0.2763 0.3034 0.2870 1.19e-134 2fge:B
4 6xov:A 966 982 0.2223 0.2474 0.2434 4.45e-64
5 4rpu:A 988 992 0.2260 0.2460 0.2450 7.86e-64 4l3t:A, 4l3t:B, 4nge:A, 4nge:D, 4rpu:B
6 8q1b:A 443 384 0.0819 0.1986 0.2292 3.61e-04 8q1b:L
7 1hr6:D 443 208 0.0484 0.1174 0.2500 0.044 1hr6:B, 1hr6:F, 1hr6:H, 1hr7:B, 1hr7:D, 1hr7:F, 1hr7:H, 1hr8:B, 1hr8:D, 1hr8:F, 1hr8:H, 1hr9:B, 1hr9:D, 1hr9:F, 1hr9:H
8 5cd4:I 494 55 0.0195 0.0425 0.3818 0.15 5cd4:U, 5h9e:A, 5h9f:A, 4tvx:I, 4tvx:U, 4u7u:M
9 4qyz:A 468 55 0.0195 0.0449 0.3818 0.17
10 6x5b:A 353 58 0.0177 0.0538 0.3276 0.62 6opn:A, 6opn:D, 6opn:G, 6x5b:D, 6x5b:J, 6x5c:A, 6x5c:D, 6x5c:E
11 7jrg:A 487 103 0.0270 0.0595 0.2816 1.6 8e73:A, 8e73:M, 7jrg:M, 7jrp:A, 7jrp:M
12 7r78:A 1880 117 0.0242 0.0138 0.2222 2.2
13 6lnh:C 228 62 0.0186 0.0877 0.3226 2.4 6lnh:A, 6lnh:B, 6lnh:D
14 7t02:A 1752 117 0.0242 0.0148 0.2222 2.4
15 1kc5:H 217 89 0.0205 0.1014 0.2472 2.5
16 4gw9:A 628 34 0.0112 0.0191 0.3529 2.5 4gw9:B, 4gw9:C, 4gw9:D, 5oy5:A, 5vik:A, 5viq:A, 5viv:A, 4xtq:A
17 6ofs:A 905 67 0.0167 0.0199 0.2687 3.3
18 1q2l:A 937 118 0.0298 0.0342 0.2712 3.4
19 5vyj:A 918 64 0.0195 0.0229 0.3281 3.8 1jqo:A, 1jqo:B, 6mgi:A, 6mgi:B, 5vyj:B, 5vyj:C, 5vyj:D
20 1kcs:H 217 78 0.0195 0.0968 0.2692 3.9
21 6zxb:A 293 82 0.0223 0.0819 0.2927 4.3 6zxb:B, 6zxc:A, 6zxc:B, 6zxc:C, 6zxc:D, 6zxm:A, 6zxm:B, 6zxm:C, 6zxm:D, 6zxm:E, 6zxm:F
22 3wic:A 360 124 0.0251 0.0750 0.2177 6.4 3wic:B, 3wic:C, 3wic:D, 3wid:A, 3wid:B, 3wid:C, 3wid:D, 3wie:A, 3wie:B, 3wie:C, 3wie:D
23 7v9o:A 860 39 0.0130 0.0163 0.3590 7.2 7v9n:A, 7v9p:A, 7v9p:B, 7v9q:A
24 8t41:A 859 39 0.0130 0.0163 0.3590 9.8
25 1c12:B 220 102 0.0205 0.1000 0.2157 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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