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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MERNKLARQIIDTCLEMTRLGLNQGAAGNVSVRYQDGMLITPTGIPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAA
YQSRPDANAVVHNHAVHCTAVSILNRSIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIAC
EVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTY

The query sequence (length=209) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2fua:A 210 209 0.9952 0.9905 0.9952 3.05e-157 1dzu:P, 1dzv:P, 1dzw:P, 1dzx:P, 1dzy:P, 1dzz:P, 1e46:P, 1e47:P, 1e48:P, 1e49:P, 1e4a:P, 1e4b:P, 1e4c:P, 1fua:A, 3fua:A, 4fua:A, 7x78:A
2 4c25:A 212 210 0.4067 0.4009 0.4048 4.97e-47 4c24:A
3 6btg:A 207 206 0.3541 0.3575 0.3592 6.49e-39 6btd:A
4 6voq:A 207 190 0.2632 0.2657 0.2895 3.86e-15
5 4xxf:A 249 215 0.2344 0.1968 0.2279 5.25e-11
6 1jdi:A 223 124 0.1914 0.1794 0.3226 3.23e-09 1jdi:B, 1jdi:C, 1jdi:D, 1jdi:E, 1jdi:F, 1k0w:A, 1k0w:B, 1k0w:C, 1k0w:D, 1k0w:E, 1k0w:F
7 8il8:A 230 179 0.1962 0.1783 0.2291 3.16e-08 8il8:B, 8il8:C, 8il8:D
8 4m6r:A 224 110 0.1388 0.1295 0.2636 8.80e-06 4m6r:B, 4m6r:C, 4m6r:D
9 2z7b:A 237 208 0.1962 0.1730 0.1971 0.021
10 6ihv:A 221 72 0.0909 0.0860 0.2639 2.7 6ihu:A
11 7t1q:A 377 58 0.0957 0.0531 0.3448 2.7 8f8o:A, 8f8o:B, 7t1q:B
12 6ihr:A 257 72 0.0909 0.0739 0.2639 4.3 5f1m:A, 6ihl:A, 6ihs:A, 6iht:A, 6ihw:A
13 5csl:B 2072 17 0.0478 0.0048 0.5882 5.6 5ctb:A, 5ctb:C, 5ctc:A, 5ctc:B, 5ctc:C, 5cte:B, 5cte:C, 3h0s:A, 3k8x:A, 3k8x:B, 3k8x:C, 1od2:A, 1od2:B, 3pgq:A, 3pgq:C, 3tv5:A, 3tv5:B, 3tv5:C, 3tvu:A, 3tvu:B, 3tvu:C, 3tvw:A, 3tvw:B, 3tvw:C, 3tz3:A, 3tz3:B, 3tz3:C, 1w96:A, 1w96:B, 1w96:C, 4wyo:B, 4wyo:C, 4wz8:B, 4wz8:C
14 5csl:A 2050 17 0.0478 0.0049 0.5882 5.6
15 3kgd:B 342 77 0.1148 0.0702 0.3117 7.2 3kgd:A, 3kgd:C, 3kgd:D, 1qmh:B, 3tut:A, 3tux:A, 3tv1:A, 3tv1:B, 3tw3:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218