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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MERFLLNSTVLLYRLSTVSLDEVSLDERVESSVFLAQYEQARSLPDHVAKSAWSYLVQQIKQRNMKLGPVAILRLIAEKF
IKNEKGGPKIDLPMFSEWQTLMSRVSCLPIIACHQVFNPGPASQEYSFRWPLYPYHPTVEDYITRECLHETHQHLNGSTS
AEECWLDALKHPEACLRDFEKGWASQEMKQLCAQIDPSLTPRIFKDRLQIACNIREILCRVAQGVELPEWIASMQNPQQL
ANSTILHNGREYGFATVWPIDDKYSQESEFCWLTGLLEKWRFNAPEGLERLLWIYLLIQNQYLTLLVQRTMTELREETEK
SYLSRFKHAHGAGVYSQVRYLEGRFAPKSDPNKMQKLLFSVLRGYWEYLSAHMSMEWVHEKPLTISQVLDNLELVEPHGK
CVELALVPHFIKRKPKNGEAYPHALLFKDLKNQAAILMDMLKSEPRLTGWIRGVDAAANEMHAPPELFCPLFRVLAKSGI
AHFTYHVGEDFPHLISGIRSIDDALRFLPLRNGDRLGHCTAIGITPSIWKRSLPLSLSMTKETRLLDLVFIWRELRSHPE
LLRYASDAAIEAVRLAHKVFSLEEEVSITTLDQVFEMRGLLAESEGLSLWLEEYERARELVKTTGMKRPLKLYKQWLTSD
NVRKQRAEYVEVALEYLPDEAVVALQQAVMAKMADRNIAIECPPTSQYRNVSEHHIFRWMGLPGEAIEGDVPMSICLGSD
DPGIFAADLKSEFYHLFVVLTRKFGLSPADALRKVAEVNENGRIYRFHDV

The query sequence (length=770) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8fnv:A 770 770 1.0000 1.0000 1.0000 0.0 8fnv:B, 8fnv:C, 8fnv:D, 8fnv:E, 8fnv:F, 8fnv:G, 8fnv:H, 8fnv:I, 8fnv:J, 8fnv:K, 8fnv:L, 8fnw:A, 8fnw:B, 8fnw:C, 8fnw:D, 8fnw:E, 8fnw:F, 8fnw:G, 8fnw:H, 8fnw:I, 8fnw:J, 8fnw:K, 8fnw:L
2 5fql:A 507 122 0.0416 0.0631 0.2623 0.23 6ioz:A
3 7e43:B 324 70 0.0338 0.0802 0.3714 0.69 7e43:A
4 3ewd:A 364 142 0.0390 0.0824 0.2113 1.6 3ewc:A, 2pgf:A, 2pgr:A, 2qvn:A
5 7u1t:A 176 24 0.0143 0.0625 0.4583 2.0 1b3t:A, 1b3t:B, 8dlf:A, 8dlf:B, 8dlf:C, 8dlf:D, 6npi:B, 6npm:B, 6npp:B, 6pw2:A, 6pw2:B, 6pw2:C, 6pw2:D, 6pw2:I, 6pw2:J, 6pw2:K, 6pw2:L, 5t7x:A, 5t7x:B, 7u1t:B, 7u1t:C, 7u1t:D, 6vh6:B
6 6f92:A 760 136 0.0494 0.0500 0.2794 2.2 6f91:A, 6f91:B, 6f91:C, 6f91:D, 6f91:E, 6f91:F, 6f91:G, 6f91:H, 6f92:B, 6f92:C, 6f92:D
7 5xnx:D 321 44 0.0169 0.0405 0.2955 3.1 5xnx:C
8 7tuv:A 672 94 0.0286 0.0327 0.2340 6.7
9 1qpn:A 284 28 0.0143 0.0387 0.3929 7.0 1qpn:B, 1qpn:C, 1qpn:D, 1qpn:E, 1qpn:F, 1qpq:A, 1qpq:B, 1qpq:C, 1qpq:D, 1qpq:E, 1qpq:F, 1qpr:A, 1qpr:B, 1qpr:C, 1qpr:D, 1qpr:E, 1qpr:F
10 8v9l:x 387 62 0.0182 0.0362 0.2258 7.5 7vok:A, 7vok:B, 7vok:C, 7vok:D
11 5b7x:A 156 52 0.0182 0.0897 0.2692 8.4
12 5bju:A 340 97 0.0338 0.0765 0.2680 9.9 5bju:B, 5bjv:A, 5bjv:B, 5bjw:A, 5bjw:B, 5bjx:A, 5bjx:B, 5bjy:A, 5bjy:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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