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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MEKVRYGIIGVGNQGGAYAGFLTGTCPPHCALGALCDIDPQKEEMCKEKYPDVPFYKDWKDMVASGDVDAVITTVPHYLH
TEIAIYCLEHGMNVLVEKPAGVYAKSVREMNECAAAHPEVTFGIMFNQRTNKLYQKIREIVASGELGEIRRSNWIINNWY
RPDSYYRLSDWRATWGGEGGGVLVNQAPHQLDLWQWICGIPTTVYANCINGSHRDIAVENDVTVLTEYENGATGSFITCT
HDLLGTDRFEIDLDGGKIVVEDSKKAYIYRFKETETAVNARDMDWMQIAMLTSDKMFEVEEFENTDGWGYQHTTVMENFA
QHIIDGTPLLAPGSDGINGVRLANAIQLSGWTGEKVANPVDEDKYLAELNKRIEAEGKFPVREHH

The query sequence (length=385) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8tdi:G 386 389 0.9896 0.9870 0.9794 0.0 8tdi:L, 8tdi:J, 8tdi:A, 8tdi:C, 8tdi:D, 8tdi:E, 8tdi:F, 8tdi:H, 8tdi:I, 8tdi:B, 8tdi:K
2 3q2i:A 345 364 0.2597 0.2899 0.2747 1.31e-25
3 3q2k:C 347 365 0.2468 0.2738 0.2603 5.35e-24 3q2k:A, 3q2k:B, 3q2k:D, 3q2k:F, 3q2k:G, 3q2k:H, 3q2k:I, 3q2k:J, 3q2k:M, 3q2k:N, 3q2k:O
4 3q2k:K 322 236 0.1766 0.2112 0.2881 2.63e-21 3q2k:E, 3q2k:L, 3q2k:P
5 3cea:A 342 197 0.1481 0.1667 0.2893 2.59e-20 3cea:B, 3cea:C, 3cea:D
6 6jw7:A 342 276 0.2052 0.2310 0.2862 2.60e-19 6jw6:A, 6jw6:B, 6jw7:B, 6jw8:A, 6jw8:B
7 4n54:A 340 196 0.1221 0.1382 0.2398 1.76e-16 4n54:B, 4n54:C, 4n54:D
8 8qc8:B 367 210 0.1636 0.1717 0.3000 2.50e-14 8qc2:A, 8qc2:B, 8qc2:C, 8qc2:D, 8qc8:C, 8qc8:A
9 8qc8:D 339 208 0.1636 0.1858 0.3029 3.12e-14
10 7x2y:A 342 201 0.1584 0.1784 0.3035 6.62e-14 7x1x:A, 7x1x:B, 7x2y:B
11 1h6d:A 383 362 0.2156 0.2167 0.2293 2.33e-12 1evj:A, 1evj:B, 1evj:C, 1evj:D, 1h6a:A, 1h6a:B, 1h6b:A, 1h6b:B, 1h6c:A, 1h6c:B, 1h6d:C, 1h6d:B, 1h6d:D, 1h6d:E, 1h6d:G, 1h6d:F, 1h6d:H, 1h6d:I, 1h6d:K, 1h6d:J, 1h6d:L, 1ofg:A, 1ofg:D, 1ofg:B, 1ofg:C, 1ofg:E, 1ofg:F, 1ryd:A, 1ryd:B, 1rye:A, 1rye:D, 1rye:B, 1rye:C
12 3ec7:A 336 146 0.1065 0.1220 0.2808 2.01e-11 3ec7:B, 3ec7:C, 3ec7:D, 3ec7:E, 3ec7:F, 3ec7:G, 3ec7:H
13 1zh8:A 325 264 0.1688 0.2000 0.2462 2.24e-11 1zh8:B
14 2o4u:X 331 242 0.1584 0.1843 0.2521 1.53e-10 2poq:X
15 9azo:A 315 188 0.1325 0.1619 0.2713 3.44e-10 9azo:B, 9azo:C, 9azo:D, 9azo:E, 9azo:F
16 8qc6:A 366 208 0.1403 0.1475 0.2596 7.33e-10 8qc3:A, 8qc3:B, 8qc5:A, 8qc5:B, 8qc6:B
17 6o15:A 355 238 0.1688 0.1831 0.2731 1.04e-09 6o15:B
18 6z3c:AAA 379 230 0.1429 0.1451 0.2391 5.66e-09 6z3b:A, 6z3b:B, 6z3c:BBB
19 3e18:A 348 269 0.1481 0.1638 0.2119 9.22e-09 3e18:B
20 2glx:A 332 196 0.1273 0.1476 0.2500 1.10e-08 2glx:B, 2glx:C, 2glx:D, 2glx:E, 2glx:F
21 3m2t:A 342 149 0.0935 0.1053 0.2416 2.42e-08 3m2t:B
22 7xre:C 363 212 0.1377 0.1460 0.2500 2.56e-08 7xr9:A, 7xr9:B, 7xr9:C, 7xr9:D, 7xr9:E, 7xr9:F, 7xre:A, 7xre:B, 7xre:D, 7xre:E, 7xre:F
23 6a3j:C 378 281 0.1766 0.1799 0.2420 7.53e-08 6a3g:A, 6a3g:B, 6a3g:C, 6a3g:D, 6a3i:A, 6a3i:B, 6a3i:C, 6a3i:D, 6a3j:A, 6a3j:B, 6a3j:D
24 6nor:A 349 182 0.1273 0.1404 0.2692 8.79e-08 6nor:B, 6nor:C, 6nor:D, 6nor:E, 6nor:F
25 7d5m:A 389 274 0.1610 0.1594 0.2263 9.92e-07 7d5n:A, 7d5n:B
26 4koa:A 333 197 0.1299 0.1502 0.2538 1.41e-06
27 5uhw:A 342 251 0.1455 0.1637 0.2231 2.86e-06 5uhw:B, 5uhz:A, 5uhz:B, 5ui9:A, 5ui9:B, 5uia:A, 5uia:B, 5uib:A, 5uib:B
28 3dty:A 374 206 0.1247 0.1283 0.2330 4.04e-06 3dty:E
29 8tdf:A 452 169 0.1169 0.0996 0.2663 1.32e-05 8tdf:B, 8tdf:C, 8tdf:D, 8tdh:B, 8tdh:C, 8tdh:D, 8tdh:A
30 5a03:C 336 251 0.1532 0.1756 0.2351 2.24e-05 5a02:A, 5a02:B, 5a02:C, 5a02:D, 5a02:E, 5a02:F, 5a03:A, 5a03:B, 5a03:D, 5a03:E, 5a03:F, 5a04:A, 5a04:B, 5a04:C, 5a04:D, 5a04:E, 5a04:F, 5a05:A, 5a05:C, 5a05:D, 5a05:E, 5a05:B, 5a05:F, 5a06:A, 5a06:B, 5a06:C, 5a06:D, 5a06:E, 5a06:F
31 6ktk:C 368 147 0.1013 0.1060 0.2653 1.00e-04 6ktk:A, 6ktk:B, 6ktk:D, 6ktl:A, 6ktl:B, 6ktl:C, 6ktl:D, 5ya8:A, 5ya8:B, 5ya8:C, 5ya8:D, 5yap:A, 5yap:B, 5yap:C, 5yap:D, 5yaq:A, 5yaq:B, 5yaq:C, 5yaq:D
32 4min:A 339 145 0.0779 0.0885 0.2069 0.004 4min:B, 4min:C, 4min:D, 4mio:A, 4mio:B, 4mio:C, 4mio:D, 4miy:A, 4miy:B, 4miy:C, 4miy:D, 4mjl:A, 4mjl:B, 4mjl:C, 4mjl:D
33 3o9z:A 310 181 0.0961 0.1194 0.2044 0.053 3o9z:B, 3o9z:C, 3o9z:D, 3oa0:A, 3oa0:B, 3oa0:C, 3oa0:D
34 7cgq:A 306 106 0.0675 0.0850 0.2453 0.17 7cgq:B, 7cgq:C, 7cgq:D, 7cgr:A, 7cgr:B, 7cgr:C, 7cgr:D, 6jnk:A, 6jnk:B, 6jnk:C, 6jnk:D
35 3rc1:A 325 93 0.0623 0.0738 0.2581 0.49 3rbv:A, 3rc2:A, 3rc7:A, 3rc9:A, 3rcb:A
36 4l8v:A 337 146 0.0779 0.0890 0.2055 0.52 4l8v:B, 4l8v:C, 4l8v:D, 3nt2:A, 3nt2:B, 3nt4:A, 3nt4:B, 3nt5:A, 3nt5:B, 3ntq:A, 3ntq:B, 3ntr:A, 3ntr:B
37 1ynk:H 219 106 0.0727 0.1279 0.2642 0.59 2cgr:H, 1ynl:H
38 6ie6:A 150 34 0.0364 0.0933 0.4118 1.3
39 5b3u:B 317 58 0.0338 0.0410 0.2241 2.3 5b3v:B, 5b3v:A, 5b3v:C, 5b3v:D
40 6z7w:B 220 77 0.0649 0.1136 0.3247 2.4 6z7w:D, 6z7w:F, 6z7w:H
41 7n3z:A 379 143 0.0883 0.0897 0.2378 3.2 7n3y:B, 7n3y:C, 7n3y:A, 7n3y:D
42 8tj5:0 1246 51 0.0338 0.0104 0.2549 3.2 8tj5:Y
43 2ixa:A 426 105 0.0727 0.0657 0.2667 3.4 2ixb:A
44 6bb4:H 216 91 0.0649 0.1157 0.2747 3.4 6bb4:I, 6bb4:J
45 5nbw:H 216 106 0.0779 0.1389 0.2830 3.8 5nbw:B
46 6t2b:B 439 115 0.0805 0.0706 0.2696 6.0 6t2b:A, 6t2b:C, 6t2b:D
47 5hvk:A 298 30 0.0312 0.0403 0.4000 7.7 8aau:L, 7ats:A, 7atu:A, 7atu:B, 7atu:C, 7atu:D, 7b8w:A, 7b8w:B, 7b8w:C, 7b8w:D, 5hvj:A, 5hvk:C, 5l6w:L, 5nxc:L, 3s95:A, 3s95:B
48 6fog:A 218 73 0.0571 0.1009 0.3014 9.0 6fog:C, 6fog:G, 6fog:E, 6fog:F, 6fog:H, 6fog:D, 6fog:B, 6foh:A, 6foh:B, 1saw:A, 1saw:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218