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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MEKFRVIGSTQPLQGEVTISGAKNAALPILFASILAEEPVEVANVPHLRDIDTTMELLERLGAKVERNGSVHVDAGPINQ
YCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHIHGLEQLGATITLEDGYVKAHVDGRLQGAHIVMD
KVSVGATITIMCAATLAEGTTVLDNAAREPEIVDTAMFLNKLGAKISGAGTDSITIEGVERLGGGKHAVVPDRIETGTFL
VAAAVSRGKIVCRNTHAHLLEAVLAKLEEAGAEIECGEDWISLDMTGRELKAVTVRTAPHPGFPTDMQAQFTLLNMMAKG
GGVITETIFENRFMHVPELKRMGAKAEIEGNTVICGDVDRLSGAQVMATDLRASASLVIAGCIAKGETIVDRIYHIDRGY
ERIEDKLSALGANIERFR

The query sequence (length=418) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4r7u:C 419 418 1.0000 0.9976 1.0000 0.0 4r7u:A, 4r7u:B, 4r7u:D
2 3vcy:A 419 416 0.8612 0.8592 0.8654 0.0 3vcy:B, 3vcy:C, 3vcy:D
3 4e7b:A 419 418 0.8086 0.8067 0.8086 0.0 1a2n:A, 4e7b:B, 4e7b:C, 4e7b:D, 4e7c:A, 4e7c:B, 4e7d:A, 4e7e:A, 4e7e:D, 4e7f:A, 1eyn:A, 3iss:A, 3iss:B, 3iss:C, 3iss:D, 3iss:E, 3iss:F, 3iss:G, 3iss:H, 3iss:I, 3iss:J, 3iss:K, 3iss:L, 3kqa:A, 3kqa:B, 3kqa:C, 3kqa:D, 3kqj:A, 3kr6:A, 3lth:A, 1q3g:A, 1q3g:B, 1q3g:C, 1q3g:D, 1q3g:E, 1q3g:F, 1q3g:G, 1q3g:H, 1q3g:I, 1q3g:J, 1q3g:K, 1q3g:L, 1q3g:W, 1q3g:X, 1q3g:Y, 1q3g:Z, 1ryw:A, 1ryw:B, 1ryw:C, 1ryw:D, 1ryw:E, 1ryw:F, 1ryw:G, 1ryw:H, 3su9:A, 3swa:A, 3swa:B, 3swd:A, 3swd:B, 3swd:C, 3swd:D, 3swd:E, 3swd:F, 3swd:G, 3swd:H, 3swd:I, 3swd:J, 3swd:K, 3swd:L, 3swi:A, 3swq:A, 1uae:A, 3upk:A, 3v4t:A, 3v4t:B, 3v4t:C, 3v4t:D, 3v4t:E, 3v4t:F, 3v4t:G, 3v4t:H, 1ybg:A, 1ybg:B, 1ybg:C, 1ybg:D, 2z2c:A, 2z2c:B, 2z2c:C, 2z2c:D
4 2rl1:A 420 419 0.7153 0.7119 0.7136 0.0 2rl2:A, 3swe:A
5 6cn1:A 422 419 0.6053 0.5995 0.6038 3.19e-176 6cn1:B, 6cn1:C, 6cn1:D, 6cn1:E, 6cn1:F, 6cn1:G, 6cn1:H
6 5bq2:A 425 419 0.6005 0.5906 0.5990 1.25e-174 5bq2:B, 5bq2:C, 5bq2:D
7 5u4h:A 420 417 0.5646 0.5619 0.5659 3.16e-167 5u4h:B
8 6q03:A 416 411 0.4904 0.4928 0.4988 8.93e-140 6q0a:A, 6q0y:A, 6q11:A
9 5wi5:A 422 422 0.5167 0.5118 0.5118 6.20e-134 6nkj:A, 6nkj:B, 5wi5:B, 5wi5:C, 5wi5:D
10 8d84:A 420 420 0.4809 0.4786 0.4786 2.20e-115 8d84:B, 8d84:C, 8d84:D, 8d84:E, 8d84:F, 8d84:G, 8d84:H, 8d84:I, 8d84:J, 8d84:K, 8d84:L, 7tb0:A, 7tb0:B, 7tb0:C, 7tb0:D
11 3swg:A 417 415 0.4498 0.4508 0.4530 1.33e-112 2yvw:A
12 1rf4:A 427 424 0.2560 0.2506 0.2524 7.38e-06 1rf4:B, 1rf4:C, 1rf4:D, 1rf6:A, 1rf6:B, 1rf6:C, 1rf6:D
13 1rf4:A 427 102 0.0622 0.0609 0.2549 1.0 1rf4:B, 1rf4:C, 1rf4:D, 1rf6:A, 1rf6:B, 1rf6:C, 1rf6:D
14 3nvs:A 426 291 0.1627 0.1596 0.2337 9.23e-05
15 2gg6:A 445 443 0.2584 0.2427 0.2438 0.031 2gga:A, 2ggd:A, 2pqb:A, 2pqc:A, 2pqd:A
16 3slh:D 440 443 0.2201 0.2091 0.2077 0.039 4egr:A, 4egr:B, 4egr:C, 4egr:D, 4egr:E, 4egr:F, 3slh:A, 3slh:B, 3slh:C, 4znd:A
17 8umj:A 443 414 0.2297 0.2167 0.2319 0.14 8umj:B, 8umk:A, 8umk:B, 8uml:A, 8uml:B, 8umm:A, 8umm:B, 8umn:A, 8umn:B
18 1dxy:A 330 104 0.0694 0.0879 0.2788 0.22
19 7zjw:LH 232 79 0.0550 0.0991 0.2911 0.53 7a01:R2, 8a3d:H, 8b5l:E, 8b6c:E, 9bdl:AL06, 9bdn:AL06, 9bdp:AL06, 7bhp:LE, 8bhf:n3, 8bpo:E2, 6d90:E, 6d9j:E, 7f5s:LE, 8fkq:SC, 8fks:SC, 8fkx:SC, 8fky:SC, 8fkz:SC, 8fl2:SC, 8fl3:SC, 8fl4:SC, 8fl6:SC, 8fl7:SC, 8fl9:SC, 8fla:SC, 8flb:SC, 8flc:SC, 8fld:SC, 8fle:SC, 8flf:SC, 9fpz:LE, 9fq0:LE, 8g5y:LE, 8g5z:LE, 8g60:LE, 8g61:LE, 8g6j:LE, 8glp:LE, 6hcf:E3, 6hcj:E3, 6hcm:E3, 6hcq:E3, 8jdj:K, 8jdk:K, 8jdl:K, 8jdm:K, 8k2c:LE, 7ls1:H2, 7ls2:H2, 6lu8:o, 5lzs:E, 5lzt:E, 5lzu:E, 5lzv:E, 5lzw:E, 5lzx:E, 5lzy:E, 5lzz:E, 7mdz:E, 6mtb:E, 6mtc:E, 6mtd:E, 6mte:E, 7nwg:E3, 7nwh:E, 8ohd:LE, 8oj0:LE, 8oj5:LE, 8oj8:LE, 7ow7:H, 7oyd:E, 6p5i:AE, 6p5j:AE, 6p5k:AE, 6p5n:AE, 7qvp:LE, 7qvp:ME, 6r5q:E, 6r6g:E, 6r7q:E, 8rjb:E, 8rjc:E, 8rjd:E, 8scb:E, 6sgc:E2, 6t59:E3, 7toq:AL06, 7tor:AL06, 7ucj:E, 7uck:E, 6w6l:G, 7xnx:LE, 7xny:LE, 8xsy:LE, 8xsz:LE, 6y0g:LE, 8y0x:LE, 6y2l:LE, 6y57:LE, 8yoo:LE, 8yop:LE, 6zvk:R2
20 5erl:D 258 30 0.0359 0.0581 0.5000 2.6 5ep9:A, 5ep9:B, 5ep9:C, 5ep9:D, 5equ:A, 5equ:B, 5equ:C, 5equ:D, 5erl:A, 5erl:B, 5erl:C
21 2oi6:B 452 188 0.1077 0.0996 0.2394 2.8 4aa7:A, 4aa7:B, 1fwy:A, 1fwy:B, 1hv9:A, 1hv9:B, 2oi5:A, 2oi5:B, 2oi6:A, 2oi7:A, 2oi7:B, 3twd:A, 3twd:B
22 6w2z:B 261 39 0.0383 0.0613 0.4103 3.5 6w2z:A
23 4le4:D 247 43 0.0311 0.0526 0.3023 5.8
24 8fkp:SC 199 86 0.0550 0.1156 0.2674 6.2 8fkr:SC, 8fkt:SC, 8fkv:SC
25 4qbo:A 92 65 0.0478 0.2174 0.3077 8.1
26 8v9j:K 102 20 0.0287 0.1176 0.6000 9.2 8v9k:K
27 7oy8:H 257 132 0.0813 0.1323 0.2576 9.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218