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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MEKETGPEVDDSKVTYDTIQSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAEYLM
KLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDESKLLSSISFLGNALVSVSSDQTGAKFDGATMSNN
THVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLAAGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAY
KGIVFPEYTKELPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQNPFLMTLDGIKK
INLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKN
PDGSYSYGWNWLDQGINIDAAYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAI
QWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLLGGYSMKDFEGWQGRSDYNG
YVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYKWTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGR
VIQDGSAYLTPWNWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKITLDLLA
NQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQGANDMLRIQGNKEKVSLTQKLTGLKPNT
KYAVYVGVDNRSNAKASITVNTGEKEVTTYTNKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGADVSNVTLTL
SREAGDEATYFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEKHDPYTQRGWNGKK
VDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEYEAGSDNTYAFVVGKGEFQSQASNLEMHELPNTWTD
SKKAKKATFLVTGAETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLT

The query sequence (length=1106) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3ecq:B 1347 1110 0.9946 0.8166 0.9910 0.0 5a55:A, 5a56:A, 5a57:A, 5a58:A, 5a59:A, 5a5a:A, 3ecq:A
2 6qfo:A 1348 1129 0.5009 0.4110 0.4907 0.0 8a19:A, 8a1a:A, 6qep:A, 6qev:B, 6qfk:A, 6sh9:B, 2zxq:A
3 5wzr:A 630 150 0.0344 0.0603 0.2533 0.006 5wzn:A, 5wzn:B, 5wzp:A, 5wzp:B, 5wzq:A, 5wzq:B, 5wzr:B
4 5x7u:A 546 83 0.0208 0.0421 0.2771 0.10
5 5jy7:B 571 83 0.0217 0.0420 0.2892 0.13 5jy7:A, 5jy7:C, 5jy7:D, 5jy7:E, 5jy7:F, 5jy7:G, 5jy7:H, 3zo9:A, 3zo9:B, 3zoa:B, 3zoa:A
6 3wy1:A 535 59 0.0181 0.0374 0.3390 0.18 3wy1:B, 3wy2:A, 3wy2:B, 3wy3:A, 3wy3:B, 3wy4:A
7 6y9t:A 536 97 0.0253 0.0522 0.2887 0.23 6y9t:B
8 4lxf:B 546 83 0.0199 0.0403 0.2651 0.91
9 8uzh:B 626 83 0.0199 0.0351 0.2651 0.94 4lxf:A, 8uqv:A, 8uqv:B, 8uqv:C, 8uqv:D, 8uzh:A
10 7yqg:B 301 136 0.0316 0.1163 0.2574 2.5 7yqg:A
11 8ibk:A 546 97 0.0253 0.0513 0.2887 2.8 8ids:A, 5zcb:A, 5zcc:A, 5zcd:A, 5zce:A
12 6lga:A 570 45 0.0136 0.0263 0.3333 7.6 6lga:B, 6lgb:A, 6lgb:B, 6lgc:A, 6lgc:B, 6lgd:A, 6lgd:B, 6lge:A, 6lge:B, 6lgf:A, 6lgf:B, 6lgg:A, 6lgg:B, 6lgh:A, 6lgh:B, 6lgi:A, 6lgi:B
13 4v2s:A 71 52 0.0145 0.2254 0.3077 7.9 7ogm:D, 4v2s:B, 4v2s:C, 4v2s:D, 4v2s:E, 4v2s:F, 2ylc:A
14 6cnh:A 321 35 0.0108 0.0374 0.3429 8.7
15 6pk6:A 338 35 0.0108 0.0355 0.3429 9.2 4ifc:A, 4ifc:B, 4iir:A, 4iir:B, 4ijp:A, 4ijp:B, 6pjj:A, 6pjj:B, 6pjj:C, 6pjj:D, 6qx9:K

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218