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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
MEIKVREMKENRLLGRKEIYFDVIHEGEATPSRADVKGKLVAMLDLNPETVVIQYIRSYFGSRVSRGYAKAYESKERMLY
IEPEYVLVRDGIIKKEE

The query sequence (length=97) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 6tmf:X 97 97 1.0000 1.0000 1.0000 3.68e-66
2 5jb3:V 99 97 0.7732 0.7576 0.7732 6.48e-54 5jbh:V, 6sw9:V, 6swc:V, 6swd:V, 4v4n:BV, 4v6u:AV, 4v6u:B6, 7zag:V, 7zah:V, 7zai:V, 7zhg:V
3 6skf:Aw 95 95 0.7835 0.8000 0.8000 6.54e-54 6skg:Aw, 6skg:Bn, 6th6:Aw
4 8auv:H 127 96 0.3711 0.2835 0.3750 4.56e-16 8b2l:H1, 7qix:U, 7qiz:KA
5 4v6w:AY 126 95 0.3196 0.2460 0.3263 9.29e-15 6xu6:AY, 6xu7:AY, 6xu8:AY
6 4v7e:BY 138 98 0.3196 0.2246 0.3163 1.25e-13 8ip8:ba, 8ip9:ba, 8ipa:ba, 8ipb:ba, 8jiw:BY, 4v3p:SU
7 9bh5:AY 123 97 0.3402 0.2683 0.3402 5.52e-13 9cai:AY
8 7r81:Z2 124 97 0.3196 0.2500 0.3196 2.34e-12
9 7olc:SY 132 97 0.3093 0.2273 0.3093 8.87e-12 7old:SY, 8oo0:SY, 5oql:y, 6rxu:Co, 6rxv:Co, 6rxx:Co, 6rxz:Co, 7z3n:SY, 7z3o:SY
10 8fvy:Y 122 93 0.2784 0.2213 0.2903 1.30e-10 8br8:Sb, 8brm:Sb, 8bsi:Sb, 8bsj:Sb, 8btd:Sb, 8btr:Sb, 8g4s:Y, 7pwf:Y, 7pwo:Y1
11 8p5d:SY0 136 73 0.2577 0.1838 0.3425 1.68e-10 8p60:SY0, 8p60:RY0, 7qca:SY0
12 3j7a:1 120 95 0.2990 0.2417 0.3053 3.00e-10 3jbn:1, 3jbo:1, 3jbp:1, 6okk:a, 8tpu:S1
13 8hkx:S24E 96 81 0.2268 0.2292 0.2716 4.87e-10 8hky:S24E, 8hkz:S24E, 8hl1:S24E, 8hl2:S24E, 8hl3:S24E, 8hl4:S24E, 8hl5:S24E, 8wkp:S24E, 8wq2:S24E, 8wq4:S24E
14 8r6f:Y 124 98 0.3299 0.2581 0.3265 1.02e-09
15 6fec:s 131 95 0.3093 0.2290 0.3158 1.98e-09 7a01:I5, 7a09:z, 5a2q:Y, 5aj0:BY, 9bdl:AS24, 9bdn:AS24, 9bdp:AS24, 8bhf:Z3, 9bkd:T, 9bln:T, 8btk:Ax, 7cpu:SY, 7cpv:SY, 4d5l:Y, 4d61:Y, 6d90:ZZ, 6d9j:ZZ, 9f1b:Ax, 9f1c:Ax, 9f1d:Ax, 5flx:Y, 6g18:Y, 6g4s:Y, 6g4w:Y, 6g51:Y, 6g53:Y, 6g5h:Y, 6g5i:Y, 8g5y:SY, 8g5z:SY, 8g60:SY, 8g61:SY, 8g6j:SY, 8glp:SY, 6gz3:BY, 6gz4:BY, 6gz5:BY, 6hcf:Z1, 6hcj:Z2, 6hcm:Z1, 6hcq:Z2, 8ifd:3N, 8ife:3N, 6ip5:3N, 6ip6:3N, 6ip8:3N, 3j7p:SY, 3j7r:SY, 3jag:YY, 3jah:YY, 3jai:YY, 3jaj:SY, 3jan:SY, 8jdj:AK, 8jdk:AK, 8jdl:AK, 8jdm:AK, 7jqb:Z, 7jqc:Z, 5k0y:s, 8k2c:SY, 7k5i:Y, 4kzx:Y, 4kzy:Y, 4kzz:Y, 5lks:SY, 7ls1:Q3, 7ls2:Q3, 5lzs:YY, 5lzt:YY, 5lzu:YY, 5lzv:YY, 5lzw:YY, 5lzx:YY, 5lzy:YY, 5lzz:YY, 7mdz:YY, 7mq8:LF, 7mq9:LF, 7mqa:LF, 6mtb:YY, 6mtc:YY, 6mtd:YY, 6mte:YY, 7nwg:Z2, 7nwh:YY, 7nwi:YY, 7o7y:Ax, 7o7z:Ax, 7o80:Ax, 7o81:Ax, 5oa3:Y, 6ole:SY, 6olf:SY, 6olg:BY, 6oli:SY, 6olz:BY, 6om0:SY, 6om7:SY, 7oya:Y2, 7oyb:Y2, 7oyc:Y2, 7oyd:YY, 8oz0:e, 8p03:a, 8p09:a, 8p2k:Ax, 6p4g:Z, 6p4h:Z, 6p5i:Z, 6p5j:Z, 6p5k:Z, 6p5n:Z, 8pj1:T, 8pj2:T, 8pj3:T, 8pj4:T, 8pj5:T, 8pj6:T, 8ppk:Y, 8ppl:AY, 8q7z:Ax, 8q87:Ax, 7qgg:SY, 8qoi:SY, 7qp6:T, 7qp7:T, 7qvp:SY, 7qvp:RY, 6qzp:SY, 7r4x:Y, 6r5q:NN, 6r6g:NN, 6r6p:NN, 6r7q:NN, 8scb:YY, 6sgc:Z1, 7syg:Z, 7syh:Z, 7syi:Z, 7syj:Z, 7syk:Z, 7syl:Z, 7sym:Z, 7syn:Z, 7syo:Z, 7syp:Z, 7syq:Z, 7syr:Z, 7sys:Z, 7syt:Z, 7syu:Z, 7syv:Z, 7syw:Z, 7syx:Z, 5t2c:AQ, 8t4s:Y, 7toq:AS24, 7tor:AS24, 7tql:Y, 7ucj:YY, 7uck:YY, 4ug0:SY, 4ujc:CY, 4ujd:CY, 4uje:BY, 4v6x:AY, 5vyc:Y1, 5vyc:Y2, 5vyc:Y3, 5vyc:Y4, 5vyc:Y5, 5vyc:Y6, 6w2s:Z, 6w2t:Z, 7wts:Y, 7wtt:Y, 7wtu:Y, 7wtv:Y, 7wtw:Y, 7wtx:Y, 7wtz:Y, 7wu0:Y, 6xa1:SY, 7xnx:SY, 7xny:SY, 8xsx:SY, 8xsy:SY, 8xsz:SY, 8xxl:SY, 8xxm:SY, 8xxn:SY, 6y0g:SY, 8y0w:SY, 8y0x:SY, 6y2l:SY, 6y57:SY, 6yal:a, 6yam:a, 6yan:a, 6ybw:T, 8yoo:SY, 8yop:SY, 6z6l:SY, 6z6m:SY, 6z6n:SY, 7zjw:Sj, 7zjx:Sj, 6zlw:Y, 6zm7:SY, 6zme:SY, 6zmi:SY, 6zmo:SY, 6zmt:Y, 6zmw:T, 6zn5:Y, 6zoj:Y, 6zok:Y, 6zon:z, 6zp4:z, 6zuo:Y, 6zv6:Y, 6zvh:Y, 6zvj:z, 6zvk:I5, 6zxd:Y, 6zxe:Y, 6zxf:Y, 6zxg:Y, 6zxh:Y
16 8c3a:a 134 97 0.3093 0.2239 0.3093 3.12e-09 8c3a:DL, 8cq7:a, 8cq7:DL, 8cqw:a, 8cqw:DL, 8cre:a, 8cre:DL, 8oeq:a, 8oeq:DL, 7pzy:Z, 7q08:Z, 7q0f:Z, 7q0p:Z, 7q0r:Z, 8q5i:Z
17 7a1g:d 134 97 0.3196 0.2313 0.3196 5.19e-09 7ajt:DY, 7aju:DY, 7b7d:d, 8bn3:D4, 8bqd:d, 8bqx:d, 8c00:d, 8c01:d, 8c83:d, 8cah:d, 8cas:d, 8cbj:Y, 8ccs:0, 8cdl:0, 8cdr:0, 8ceh:0, 8cf5:0, 8cg8:0, 8cgn:0, 8civ:0, 8cku:0, 8cmj:0, 7d4i:SZ, 7d5t:SZ, 7d63:SZ, 5dat:D4, 5dat:d4, 5dc3:D4, 5dc3:d4, 5dge:D4, 5dge:d4, 5dgf:D4, 5dgf:d4, 5dgv:D4, 5dgv:d4, 6eml:d, 8eub:BY, 8evp:BY, 8evq:BY, 8evr:BY, 8evs:BY, 8evt:BY, 8ewb:BY, 8ewc:BY, 6fai:Y, 5fci:D4, 5fci:d4, 5fcj:D4, 5fcj:d4, 6fyx:Y, 6fyy:Y, 6gq1:AO, 6gqb:AO, 6gqv:AO, 6gsm:Y, 6gsn:Y, 6hhq:Z, 6hhq:d4, 5i4l:D4, 5i4l:d4, 6i7o:d, 6i7o:db, 8i7j:Y, 5it7:Y, 5it9:Y, 3j16:D, 3j6x:24, 3j6y:24, 3j77:24, 3j78:24, 3j80:Y, 3j81:Y, 3jam:Y, 3jap:Y, 5juo:VB, 5jup:VB, 5jus:VB, 5jut:VB, 5juu:VB, 8k2d:SY, 8k82:SY, 6ke6:SZ, 5ll6:d, 6lqp:SZ, 6lqq:SZ, 6lqr:SZ, 6lqs:SZ, 6lqt:SZ, 6lqu:SZ, 6lqv:SZ, 5lyb:D4, 5lyb:d4, 5m1j:Y2, 5mc6:d, 5mei:d4, 5mei:Z, 7mpi:BY, 7mpj:BY, 7n8b:BY, 5ndg:D4, 5ndg:d4, 5ndv:D4, 5ndv:d4, 5ndw:D4, 5ndw:d4, 7nrc:Sd, 7nrd:Sd, 5obm:D4, 5obm:d4, 5on6:d4, 5on6:Z, 7osa:eS24, 7osm:eS24, 6q8y:d, 6rbd:Y, 6rbe:Y, 7rr5:SY, 8rw1:Y, 6s47:BZ, 8s8d:Y, 8s8e:Y, 8s8f:Y, 8s8g:Y, 8s8h:Y, 8s8i:Y, 8s8j:Y, 6snt:Y, 7suk:LF, 6sv4:d, 6sv4:db, 6sv4:dc, 6t4q:SY, 6t7i:SY, 6t7t:SY, 6t83:Yb, 6t83:z, 5tbw:Z, 5tbw:d4, 6tb3:d, 5tga:D4, 5tga:d4, 5tgm:D4, 5tgm:d4, 6tnu:d, 4u3m:D4, 4u3m:d4, 4u3n:D4, 4u3n:d4, 4u3u:D4, 4u3u:d4, 4u4n:D4, 4u4n:d4, 4u4o:D4, 4u4o:d4, 4u4q:D4, 4u4q:d4, 4u4r:D4, 4u4r:d4, 4u4u:D4, 4u4u:d4, 4u4y:D4, 4u4y:d4, 4u4z:D4, 4u4z:d4, 4u50:D4, 4u50:d4, 4u51:D4, 4u51:d4, 4u52:D4, 4u52:d4, 4u53:D4, 4u53:d4, 4u55:D4, 4u55:d4, 4u56:D4, 4u56:d4, 4u6f:D4, 4u6f:d4, 4uer:P, 6uz7:Y, 4v6i:AU, 4v88:AY, 4v88:CY, 4v8y:AY, 4v8z:AY, 4v92:BY, 6wdr:Y, 5wlc:LF, 6woo:YY, 7wtl:SY, 7wtm:SY, 7wtn:SY, 7wto:SY, 7wtp:SY, 7wtq:SY, 7wtr:SY, 5wyj:SZ, 5wyk:SZ, 6xiq:AO, 6xir:AO, 8y0u:SY, 6y7c:Y, 6z6j:SY, 6z6k:SY, 6zce:Z, 7zpq:AY, 6zqb:DY, 6zqc:DY, 6zqd:DY, 6zqe:DY, 6zqf:DY, 6zqg:DY, 7zrs:AY, 6zu9:d, 7zuw:AY, 7zux:DY, 6zvi:I, 7zw0:sd
18 4bts:AP 148 85 0.2474 0.1622 0.2824 1.39e-08 4bts:BP, 4bts:CP, 4bts:DP, 5jpq:0, 4v5o:AP, 4v5o:BP
19 7qep:D4 127 89 0.2371 0.1811 0.2584 4.81e-08
20 6zj3:SZ 127 98 0.2680 0.2047 0.2653 1.75e-07
21 5xxu:Y 128 94 0.2371 0.1797 0.2447 3.61e-06
22 6rm3:SY0 125 88 0.2268 0.1760 0.2500 6.03e-06
23 6zu5:SY0 123 88 0.2165 0.1707 0.2386 1.62e-05
24 5xyi:Y 105 90 0.2784 0.2571 0.3000 2.01e-05
25 7w6l:C 158 51 0.1753 0.1076 0.3333 0.71 5f59:A, 5f6k:C, 5f6k:E, 6kiw:K, 7w6l:E
26 3k7l:A 409 56 0.1546 0.0367 0.2679 0.74
27 8yhd:G 234 59 0.2165 0.0897 0.3559 0.77 8yhe:G, 8z4j:G, 8z4l:G, 8z99:G, 8z9c:G
28 4z4p:A 161 60 0.2062 0.1242 0.3333 0.83
29 4zcf:A 616 34 0.1134 0.0179 0.3235 2.6 4zcf:B
30 7og0:B 498 59 0.1649 0.0321 0.2712 3.7 7ofw:A, 7ofz:A, 7og0:A
31 7tgk:D 593 73 0.1959 0.0320 0.2603 4.0 7tgk:B, 7tgk:E, 7tgk:A, 7tgk:C, 7tgl:A, 7tgl:B, 7tgl:C, 7tgl:D, 7tgl:E, 7tgm:A, 7tgm:B, 7tgm:C, 7tgm:E, 7tgm:D
32 4gxg:A 209 32 0.1237 0.0574 0.3750 4.1 2bv7:A, 2euk:A, 2eum:A, 2evd:A, 2evl:A, 2evs:A, 2evs:E, 4gh0:A, 4ghp:A, 4ghs:A, 4ghs:B, 4gix:A, 4gjq:A, 4gjq:B, 4gvt:A, 4gxd:A, 4gxg:B, 4gxg:D, 4gxg:E, 4h2z:A, 3ric:A, 3rzn:A, 3s0i:A, 3s0k:A, 1sx6:A
33 1xvx:A 311 30 0.1031 0.0322 0.3333 4.8
34 8z9e:G 175 28 0.1340 0.0743 0.4643 5.4
35 7lgb:A 282 65 0.1959 0.0674 0.2923 6.0
36 3ax7:A 1225 31 0.1134 0.0090 0.3548 7.2 3ax7:B, 3ax9:A, 3ax9:B
37 1fo4:A 1299 31 0.1134 0.0085 0.3548 7.3 3am9:A, 3am9:B, 3amz:A, 3amz:B, 3b9j:B, 3b9j:C, 3b9j:J, 3b9j:K, 3bdj:A, 3bdj:B, 3etr:B, 3etr:C, 3etr:M, 3etr:N, 3eub:B, 3eub:C, 3eub:K, 3eub:L, 3eub:T, 3eub:U, 3eub:3, 3eub:4, 1fiq:B, 1fo4:B, 8j79:A, 8j79:B, 1n5x:A, 1n5x:B, 3nrz:B, 3nrz:C, 3nrz:K, 3nrz:L, 3ns1:B, 3ns1:C, 3ns1:K, 3ns1:L, 3nvv:B, 3nvv:C, 3nvv:K, 3nvv:L, 3nvw:B, 3nvw:C, 3nvw:K, 3nvw:L, 3nvy:B, 3nvy:C, 3nvy:K, 3nvy:L, 3nvz:B, 3nvz:C, 3nvz:K, 3nvz:L, 3sr6:B, 3sr6:C, 3sr6:K, 3sr6:L, 3una:A, 3una:B, 3unc:A, 3unc:B, 3uni:A, 3uni:B, 1v97:A, 1v97:B, 1vdv:A, 1vdv:B
38 8ro2:C 908 38 0.1443 0.0154 0.3684 8.4 7aav:r, 7abf:r, 7abg:r, 7abi:r, 6ah0:C, 6ahd:C, 8c6j:C, 8ch6:b, 7dvq:C, 6ff4:B, 6ff7:B, 9fmd:C, 8h6e:5C, 8h6j:5C, 8h6k:5C, 8h6l:5C, 8i0p:C, 8i0r:C, 8i0s:C, 8i0t:C, 8i0u:C, 8i0v:C, 8i0w:C, 6icz:C, 6id0:C, 6id1:C, 8q7q:C, 8q7v:C, 8q7w:C, 8q7x:C, 8q91:C, 6qdv:C, 8qp8:C, 7qtt:b, 6qw6:5C, 6qx9:5C, 8rc0:C, 7w59:C, 7w5a:C, 7w5b:C, 5xjc:C, 8y6o:D, 5yzg:C, 5z56:C, 5z57:C, 5z58:C, 6zym:B
39 4p7a:A 303 30 0.1237 0.0396 0.4000 9.8
40 8qjd:A 1037 52 0.1856 0.0174 0.3462 9.8 8qjd:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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