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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MEDPMYEQFLQRIQAVRTATVAKDISADILEARHDYFGRELCRALDIEYRNNVLLDEIILDVYPGVNLMEYNVPHVTPDN
YIWTGDMLLILDYKVSVGHDSTEVTYKAYTTLILPVMQEIGINTEICIIRANPVTNQISIVGEQFKRLFPTIPVELNFAR
FFELRKMLLDKFADDEEFLMMIA

The query sequence (length=183) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ewx:B 183 183 0.9891 0.9891 0.9891 2.50e-134 7ewu:B, 7ewu:C, 7ewu:D, 7ewv:A, 7eww:A, 7eww:B, 7ewx:A, 7ewz:A, 7ewz:B, 7ex0:A, 7ex0:B, 7ex2:A, 7ex2:B, 7ex3:A, 7ex4:A, 7ex6:A, 7ex6:B, 7ex6:C, 7ex6:D, 7ex7:A, 7ex7:B, 7ex7:C, 7ex7:D, 7ex8:A, 7ex9:A
2 6z6b:PPP 2036 178 0.4918 0.0442 0.5056 7.12e-53 6z6b:EEE
3 6z8k:A 2158 178 0.4918 0.0417 0.5056 8.42e-53 5amq:A, 7orn:A
4 6z6g:A 2142 178 0.4918 0.0420 0.5056 8.92e-53 5amr:A
5 7oro:A 2008 178 0.4863 0.0443 0.5000 1.09e-51 7ori:A
6 7orj:A 2129 178 0.4863 0.0418 0.5000 1.20e-51
7 7orm:A 2145 178 0.4863 0.0415 0.5000 1.31e-51
8 7orl:A 2183 178 0.4863 0.0408 0.5000 1.31e-51 7oa4:AAA, 7oa4:BBB, 7oa4:DDD, 7oa4:GGG, 7ork:A, 7plr:AAA, 7plr:BBB, 7plr:DDD, 7plr:GGG, 2xi5:A, 2xi5:B, 2xi5:C, 2xi5:D, 2xi7:A, 2xi7:B, 2xi7:C, 2xi7:D
9 8ki7:A 2003 117 0.1803 0.0165 0.2821 0.060
10 7ekp:A 396 61 0.1093 0.0505 0.3279 0.47 8cau:A, 8cau:B, 8cau:C, 8cau:D, 8cau:E, 8ci1:A, 8ci1:B, 8ci1:C, 8ci1:D, 8ci1:E, 7eki:A, 7eki:B, 7eki:C, 7eki:D, 7eki:E, 7ekp:B, 7ekp:C, 7ekp:D, 7ekp:E, 7ekt:A, 7ekt:E, 7ekt:B, 7ekt:C, 7ekt:D, 7koo:A, 7koo:B, 7koo:C, 7koo:D, 7koo:E, 7koq:A, 7koq:B, 7koq:C, 7koq:D, 7koq:E, 7kox:A, 7kox:B, 7kox:C, 7kox:D, 7kox:E, 8ut1:A, 8ut1:B, 8ut1:C, 8ut1:D, 8ut1:E, 8utb:A, 8utb:B, 8utb:C, 8utb:D, 8utb:E, 8uzj:A, 8uzj:B, 8uzj:E, 8uzj:C, 8uzj:D, 8v80:A, 8v80:B, 8v80:C, 8v80:D, 8v80:E, 8v82:A, 8v82:B, 8v82:E, 8v82:C, 8v82:D, 8v86:A, 8v86:E, 8v86:B, 8v86:C, 8v86:D, 8v88:A, 8v88:B, 8v88:C, 8v88:D, 8v88:E, 8v89:A, 8v89:B, 8v89:C, 8v89:D, 8v89:E, 8v8a:A, 8v8a:B, 8v8a:E, 8v8a:C, 8v8a:D, 8v8c:C, 8v8c:D, 8v8c:E, 8v8d:A, 8v8d:B, 8v8d:E, 8v8d:C, 8v8d:D
11 8v8c:B 374 61 0.1093 0.0535 0.3279 0.48 8v8c:A
12 5xoh:A 348 84 0.1148 0.0603 0.2500 0.82
13 3d1k:B 146 63 0.0929 0.1164 0.2698 1.1 4g51:B, 4g51:D, 3gkv:B, 3gqg:B, 3gqg:D, 2h8d:B, 2h8d:D, 2h8f:B, 2h8f:D, 1hbh:B, 1hbh:D, 4iro:B, 4iro:D, 1la6:B, 5lfg:B, 5lfg:D, 3nfe:B, 3nfe:D, 3ng6:B, 3ng6:D, 4odc:B, 1pbx:B, 2peg:B, 1s5x:B, 1s5y:B, 1s5y:D, 1t1n:B
14 8iwh:3 220 67 0.0984 0.0818 0.2687 1.2 8j0d:3, 8j5k:p, 8j5k:P, 8w4p:p
15 7elb:A 1937 48 0.0820 0.0077 0.3125 1.7 7ckm:A, 7elb:C, 6kld:A, 6kle:A, 6klh:A, 6klh:C
16 5lq5:A 274 27 0.0546 0.0365 0.3704 3.2 5lq8:A
17 4omb:A 298 47 0.0601 0.0369 0.2340 4.0 4omb:B, 4omb:C, 4omb:D
18 1xl8:B 600 82 0.1530 0.0467 0.3415 4.0 1xl8:A
19 8fmw:H 132 83 0.1148 0.1591 0.2530 4.3
20 3at5:B 146 97 0.1148 0.1438 0.2165 7.6 3at6:B
21 6hit:B 145 100 0.1475 0.1862 0.2700 7.9 6hit:D, 6hit:F, 6hit:H
22 8g8v:A 254 67 0.0984 0.0709 0.2687 8.2 8g6c:A, 8g6c:B, 8g8v:B, 8tcc:A, 8tcc:B, 8tcc:C, 8tcc:D
23 6l8h:A 466 64 0.1038 0.0408 0.2969 10.0 6l8h:B, 6l8h:C, 6l8h:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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