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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MDPETVRIALGLEERTAAWLTELDELGPPAEPVRLPRGEEARDLLRRLEVPELDAEEIVAAAPDPDRDPALWWLLERTHH
AIVRHMGDHRAKPRGGPPLPYEGGAAARYFHVYVFLATVPAVRRFHAERGIPDEVGWETLTQLGELVAIHRRKYGQGGMN
MQWWTTYHLRGILYRLGRLQFSLATGKDGTPHLGLAVPEWGGPLLPKAYDESLHRARPFFDRHFPEHGARVAWGSSWMLD
PQLEEYLTEDSNIIQLARFWTLTDSAPEPGNADGDSSILEFVFRYNGQPLDELPQRSSLERAVIAHLKAGRHWHMRTGFV
KLP

The query sequence (length=323) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6iix:A 323 323 0.9969 0.9969 0.9969 0.0 4mfk:A, 4mfl:A, 4mfp:A, 4mfq:A, 4q36:A, 4q38:A
2 4mfz:A 319 323 0.7090 0.7179 0.7090 3.40e-165
3 6j18:A 272 71 0.0712 0.0846 0.3239 0.72
4 8hz5:A 350 83 0.0836 0.0771 0.3253 0.74
5 5hzi:A 476 70 0.0588 0.0399 0.2714 2.7 5djt:A, 5dju:A, 5dju:C, 5efw:A, 5hzi:B, 5hzj:A, 5hzj:B, 5hzk:B, 5hzk:D, 7pgx:AAA, 7pgy:AAA, 7pgz:AAA, 7ph0:AAA, 2v0u:A, 2v0w:A, 2v1a:A, 2v1b:A
6 2wkp:A 320 70 0.0588 0.0594 0.2714 2.9 6agp:A, 7ajk:BBB, 6bc1:A, 6bc1:B, 2c2h:A, 2c2h:B, 1ds6:A, 1e96:A, 2fju:A, 2g0n:A, 2g0n:B, 1g4u:R, 4gzl:A, 4gzl:B, 4gzm:A, 4gzm:B, 2h7v:A, 2h7v:B, 1he1:C, 1he1:D, 1hh4:A, 1hh4:B, 1i4d:D, 1i4l:D, 1i4t:D, 2ic5:A, 2ic5:B, 1mh1:A, 5n6o:A, 5n6o:B, 5o33:A, 2ov2:A, 2ov2:F, 2ov2:B, 2ov2:C, 2ov2:G, 2ov2:D, 2ov2:E, 2ov2:H, 2p2l:A, 2p2l:B, 2p2l:C, 8q0n:C, 2qme:A, 5qqd:A, 5qqe:A, 5qqf:A, 5qqg:A, 5qqh:A, 5qqi:A, 5qqj:A, 5qqk:A, 5qql:A, 5qqm:A, 5qqn:A, 2rmk:A, 1ryf:A, 1ryf:B, 1ryh:A, 1ryh:B, 3ryt:C, 3sbd:A, 3sbd:B, 3sbe:A, 3su8:A, 3sua:A, 3sua:B, 3sua:C, 3th5:A, 3th5:B, 7usd:F, 7use:F, 7use:G, 2w2t:A, 2w2v:A, 2w2v:B, 2w2v:C, 2w2v:D, 2w2x:A, 2w2x:B, 8wej:E, 2wkq:A, 2wkr:A
7 5hzh:A 320 70 0.0588 0.0594 0.2714 3.0
8 6n6a:A 181 84 0.0774 0.1381 0.2976 3.2 6n6c:A, 6n6d:A, 6n6e:A, 6n6f:A, 6n6g:A, 6n6h:A
9 3q08:A 241 70 0.0619 0.0830 0.2857 3.9 3q08:B, 3q08:C, 3q08:D, 3q08:E, 3q08:F, 3q08:G, 3q08:H, 3q08:I, 3q08:J, 3q08:K, 3q08:L, 3q08:M, 3q08:N, 3q08:O, 3q08:P, 3q08:Q, 3q08:R, 3q08:S, 3q08:T, 3q09:A, 3q09:B, 3q09:C, 3q09:D, 3q09:E, 3q09:F, 3q09:G, 3q09:H, 3q09:I, 3q09:J, 3q09:K, 3q09:L, 3q09:M, 3q09:N, 3q09:O, 3q09:P, 3q09:Q, 3q09:R, 3q09:S, 3q09:T, 2vxh:A, 2vxh:B, 2vxh:C, 2vxh:D, 2vxh:E, 2vxh:F
10 6xkw:p 254 61 0.0557 0.0709 0.2951 4.1 6xkx:p, 6xkz:p
11 7zkq:T 351 102 0.0774 0.0712 0.2451 5.0
12 7acs:A 140 31 0.0402 0.0929 0.4194 5.3 7act:A, 8iv3:D, 8j6x:A, 8j6x:D, 6vyo:A, 6vyo:B, 6vyo:C, 6vyo:D, 6wkp:B, 6wkp:C, 6wkp:D, 7xwz:A, 7xwz:B, 7xx1:A, 7xx1:B, 7xx1:C, 7xx1:D
13 8pv4:CW 550 78 0.0805 0.0473 0.3333 7.0 8pv6:CW, 8pv8:CW
14 5g31:A 105 60 0.0557 0.1714 0.3000 7.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218