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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCG
TTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKIAMSTLDG
GRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKL
FAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK

The query sequence (length=378) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ol2:F 378 378 1.0000 1.0000 1.0000 0.0 5ol2:C
2 4l1f:A 380 379 0.6323 0.6289 0.6306 5.98e-169 4l1f:B
3 5lnx:D 374 370 0.5370 0.5428 0.5486 1.39e-148 5lnx:A, 5lnx:B, 5lnx:C, 5lnx:E, 5lnx:F, 5lnx:G, 5lnx:H
4 1buc:A 383 383 0.5794 0.5718 0.5718 9.34e-148 1buc:B
5 7y0a:C 387 371 0.5159 0.5039 0.5256 4.05e-139 1jqi:A, 1jqi:B, 8sgs:A, 8sgs:B, 8sgs:C, 8sgs:D, 2vig:A, 2vig:B, 2vig:C, 2vig:D, 2vig:E, 2vig:F, 2vig:G, 2vig:H, 7y0a:A, 7y0a:B, 7y0a:D, 7y0b:A, 7y0b:B, 7y0b:C, 7y0b:D
6 3pfd:C 369 369 0.4974 0.5095 0.5095 6.95e-129 3pfd:A, 3pfd:B, 3pfd:D
7 6fah:D 379 375 0.5106 0.5092 0.5147 1.77e-128 6fah:C
8 7w0j:E 382 380 0.4974 0.4921 0.4947 5.85e-124 8i4p:A, 8i4r:A, 7w0j:B, 7w0j:C, 7w0j:H
9 4n5f:A 378 375 0.4656 0.4656 0.4693 3.80e-121 4n5f:B
10 4m9a:B 376 375 0.4735 0.4761 0.4773 2.03e-120 4m9a:A
11 7szv:A 372 371 0.4709 0.4785 0.4798 1.54e-116 7szv:B
12 1ukw:A 379 373 0.4312 0.4301 0.4370 7.17e-111 1ukw:B
13 7p9a:A 380 362 0.4577 0.4553 0.4779 5.13e-106 7p98:A, 7p98:B, 7p9a:B, 7p9x:A, 7p9x:B, 7p9x:C, 7p9x:D
14 2dvl:A 370 354 0.4550 0.4649 0.4859 2.05e-104 2dvl:B
15 2jif:A 381 364 0.4101 0.4068 0.4258 1.48e-103 2jif:C, 2jif:B, 2jif:D
16 1rx0:A 384 379 0.4312 0.4245 0.4301 2.05e-100 1rx0:C, 1rx0:B, 1rx0:D
17 8sgr:A 393 372 0.4048 0.3893 0.4113 4.12e-94 1ivh:A, 1ivh:B, 1ivh:C, 1ivh:D, 8sgr:B, 8sgr:C, 8sgr:D
18 2d29:A 386 368 0.4365 0.4275 0.4484 1.09e-92 2d29:B
19 3mdd:A 385 359 0.4021 0.3948 0.4234 3.62e-90 3mdd:B, 3mde:A, 3mde:B, 1udy:A, 1udy:B, 1udy:C, 1udy:D
20 3nf4:A 369 371 0.4074 0.4173 0.4151 1.49e-89 3nf4:B
21 2a1t:C 388 360 0.4048 0.3943 0.4250 3.56e-89 2a1t:A, 2a1t:B, 2a1t:D, 1egc:A, 1egc:B, 1egc:C, 1egc:D, 1egd:A, 1egd:B, 1egd:C, 1egd:D, 1ege:A, 1ege:B, 1ege:C, 1ege:D, 4p13:A, 4p13:B, 4p13:C, 4p13:D, 8sgp:A, 8sgp:B, 8sgp:C, 8sgp:D, 1t9g:A, 1t9g:B, 1t9g:C, 1t9g:D
22 4iv6:B 383 378 0.3995 0.3943 0.3995 1.69e-88 4iv6:A
23 2z1q:B 549 379 0.4180 0.2878 0.4169 6.75e-88 2z1q:A
24 4kto:A 377 360 0.4074 0.4085 0.4278 2.32e-87 4kto:C, 4kto:B, 4kto:D
25 3mpi:C 395 380 0.4101 0.3924 0.4079 5.48e-84 3mpi:A, 3mpi:B, 3mpi:D, 3mpj:B, 3mpj:A, 3mpj:D, 3mpj:E, 3mpj:F, 3mpj:G
26 3owa:C 587 400 0.4021 0.2589 0.3800 5.71e-82 3owa:A, 3owa:B, 3owa:D
27 8phe:A 551 356 0.3968 0.2722 0.4213 9.44e-80 8phe:B, 8phf:A, 8phf:B
28 2pg0:A 380 373 0.3704 0.3684 0.3753 1.43e-79 2pg0:B
29 4irn:A 378 372 0.3386 0.3386 0.3441 9.30e-77 4irn:B, 4irn:C, 4irn:D, 4irn:E, 4irn:F, 4irn:G, 4irn:H
30 7s7g:A 571 381 0.3862 0.2557 0.3832 1.09e-73 3b96:A, 2uxw:A
31 6es9:A 545 382 0.3836 0.2661 0.3796 7.67e-71 6es9:B
32 8w0t:A 398 375 0.3386 0.3216 0.3413 1.01e-70 8w0t:B, 8w0t:C, 8w0t:D, 8w0u:A, 8w0u:B, 8w0u:C, 8w0u:D, 8w0z:A, 8w0z:B, 8w0z:C, 8w0z:D, 8w0z:E, 8w0z:F, 8w0z:G, 8w0z:H
33 5af7:B 391 367 0.3624 0.3504 0.3733 2.12e-70 5af7:A, 5ahs:A, 5ahs:B, 5ahs:C, 5ahs:E, 5ahs:F, 5ahs:D
34 6cxt:B 372 359 0.3254 0.3306 0.3426 3.29e-70 6cy8:B
35 3r7k:A 378 376 0.3439 0.3439 0.3457 2.98e-69 3r7k:B, 3r7k:C, 3r7k:D
36 8ca1:B 589 381 0.3598 0.2309 0.3570 2.72e-68 8ca1:A
37 5idu:C 405 324 0.3466 0.3235 0.4043 9.10e-68 5idu:A, 5idu:B, 5idu:D
38 5jsc:A 388 315 0.3333 0.3247 0.4000 5.44e-66 5jsc:B, 5jsc:C, 5jsc:D
39 3oib:A 381 368 0.3624 0.3596 0.3723 4.73e-63 3oib:B, 3p4t:A, 3p4t:B
40 2eba:A 380 355 0.3360 0.3342 0.3577 1.90e-61 2eba:D, 2eba:C, 2eba:E, 2eba:F, 2eba:G, 2eba:H, 2eba:I
41 3sf6:A 387 375 0.3307 0.3230 0.3333 9.73e-61
42 7xp7:B 376 373 0.3757 0.3777 0.3807 3.28e-60 7xp7:A, 7xp7:C, 7xp7:D
43 3swo:A 388 362 0.3307 0.3222 0.3453 1.18e-58 3swo:D, 3swo:B, 3swo:C
44 3gqt:C 385 364 0.3122 0.3065 0.3242 4.91e-58 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
45 2r0m:A 390 366 0.3148 0.3051 0.3251 1.70e-56 2r0n:A, 1siq:A, 1sir:A
46 6af6:A 383 382 0.3201 0.3159 0.3168 3.55e-56 5zw2:A, 5zw7:A, 5zw8:A
47 2ix6:A 416 370 0.2910 0.2644 0.2973 1.87e-46 2ix5:A, 2ix5:B, 2ix5:C, 2ix5:D, 2ix6:C, 2ix6:F, 2ix6:B, 2ix6:E, 2ix6:D
48 8ciw:A 555 396 0.3228 0.2198 0.3081 7.39e-46 8ciw:B
49 6u1v:B 389 361 0.2937 0.2853 0.3075 2.64e-39 6u1v:A, 6u1v:C, 6u1v:D
50 4hr3:A 407 285 0.2354 0.2187 0.3123 8.96e-39
51 4x28:A 386 348 0.2778 0.2720 0.3017 2.04e-36 4x28:B
52 6wy8:B 384 349 0.2698 0.2656 0.2923 1.70e-32 6wy8:D, 6wy9:A
53 6wy8:C 364 340 0.2751 0.2857 0.3059 5.45e-32 6wy8:A, 6wy9:B
54 2wbi:B 398 289 0.2196 0.2085 0.2872 9.40e-31 2wbi:A
55 1r2j:A 353 355 0.2593 0.2776 0.2761 1.11e-30
56 4kcf:A 407 354 0.2328 0.2162 0.2486 4.97e-25 3m9v:A
57 3mkh:A 426 346 0.2407 0.2136 0.2630 6.20e-24 3mkh:B, 3mkh:C, 3mkh:D
58 6kse:A 607 320 0.2619 0.1631 0.3094 2.16e-23 6kse:B
59 4y9j:B 593 278 0.2249 0.1433 0.3058 3.10e-21 4y9j:A, 4y9l:A, 4y9l:B
60 5ez3:B 541 328 0.2434 0.1701 0.2805 8.75e-21 5ez3:A, 5ez3:C, 5ez3:D
61 6ksa:B 611 317 0.2513 0.1555 0.2997 2.66e-20 6kpt:A, 6kpt:B, 6kri:A, 6kri:B, 6ks9:A, 6ks9:B, 6ksa:A, 6ksb:A, 6ksb:B, 6lpy:A, 6lpy:B, 6lq0:A, 6lq0:B, 6lq1:A, 6lq1:B, 6lq2:A, 6lq2:B, 6lq3:A, 6lq3:B, 6lq4:A, 6lq4:B, 6lq5:A, 6lq5:B, 6lq6:A, 6lq6:B, 6lq7:A, 6lq7:B, 6lq8:A, 6lq8:B
62 4x28:D 364 352 0.2593 0.2692 0.2784 3.54e-20 4x28:C
63 3d9d:A 432 376 0.2381 0.2083 0.2394 2.92e-17 2c0u:A, 2c0u:B, 2c0u:C, 2c0u:D, 2c12:A, 2c12:B, 2c12:C, 2c12:D, 2c12:E, 2c12:F, 3d9d:B, 3d9d:C, 3d9d:D, 3d9e:A, 3d9e:B, 3d9e:C, 3d9e:D, 3d9f:A, 3d9f:B, 3d9f:C, 3d9f:D, 3d9g:A, 3d9g:B, 3d9g:C, 3d9g:D, 3fcj:A, 3fcj:B, 3fcj:C, 3fcj:D, 2reh:A, 2reh:B, 2reh:C, 2reh:D, 2zaf:A, 2zaf:B, 2zaf:C, 2zaf:D
64 5z8t:A 395 372 0.2460 0.2354 0.2500 2.97e-17 5z8t:B, 5z8t:C
65 8hk0:B 379 203 0.1481 0.1478 0.2759 1.45e-16 8hk0:A
66 6sd8:X 503 357 0.2354 0.1769 0.2493 1.25e-14 6sd8:A, 6sda:A, 6sda:B
67 4zyj:D 392 373 0.2196 0.2117 0.2225 3.04e-14 4zyj:A, 4zyj:B, 4zyj:C
68 3u33:A 540 271 0.1825 0.1278 0.2546 7.67e-14 3djl:A, 3u33:B, 3u33:C, 3u33:D, 3u33:E, 3u33:F, 3u33:G, 3u33:H, 3u33:I, 3u33:J, 3u33:K, 3u33:L
69 4xvx:B 373 350 0.2196 0.2225 0.2371 6.76e-13 4xvx:A
70 3x0y:A 402 350 0.2011 0.1891 0.2171 3.05e-12 3x0y:F, 3x0y:C, 3x0y:E, 3x0y:B, 3x0y:D
71 5ys9:A 692 218 0.1587 0.0867 0.2752 1.49e-09 5ys9:B
72 7q86:A 612 299 0.1931 0.1193 0.2441 4.17e-09 7q86:B
73 5xdc:B 402 354 0.2063 0.1940 0.2203 6.06e-09 5xdb:A, 5xdb:B, 5xdb:C, 5xdb:D, 5xdc:A, 5xdc:C, 5xdc:D, 5xdd:A, 5xdd:B, 5xdd:C, 5xdd:D, 5xde:A, 5xde:B, 5xde:C, 5xde:D, 5xdg:A, 5xdg:B, 5xdg:C, 5xdg:D
74 2rfq:A 388 382 0.2169 0.2113 0.2147 4.87e-07 2rfq:B, 2rfq:C, 2rfq:D
75 1is2:A 637 141 0.1085 0.0644 0.2908 1.36e-06 2ddh:A, 1is2:B
76 5y9d:A 687 219 0.1481 0.0815 0.2557 1.55e-06 5y9d:B
77 8hk0:C 346 172 0.1270 0.1387 0.2791 2.33e-05 8hk0:D
78 1w07:B 658 202 0.1402 0.0805 0.2624 5.17e-05 1w07:A
79 5k3i:A 661 167 0.1190 0.0681 0.2695 6.22e-05 5k3i:B, 5k3i:C, 5k3i:D, 5k3i:E, 5k3i:F, 5k3i:G, 5k3i:H
80 5k3j:A 662 216 0.1270 0.0725 0.2222 0.001 5k3j:B
81 5mr6:A 396 214 0.1270 0.1212 0.2243 1.4 5lvw:A, 5mr6:D, 5mr6:B, 5mr6:C, 5mr6:E, 5mr6:H, 5mr6:F, 5mr6:G, 5mr6:I, 5mr6:L, 5mr6:J, 5mr6:K, 5mr6:M, 5mr6:P, 5mr6:N, 5mr6:O, 5mr6:Q, 5mr6:R, 5mr6:S, 5mr6:T, 5mr6:U, 5mr6:V, 5mr6:W, 5mr6:X
82 9b6h:B 934 38 0.0423 0.0171 0.4211 3.2 9b6d:A, 9b6d:B, 9b6d:C, 9b6d:D, 9b6e:B, 9b6e:A, 9b6e:C, 9b6e:D, 9b6f:A, 9b6f:B, 9b6f:C, 9b6f:D, 9b6g:A, 9b6g:B, 9b6g:C, 9b6g:D, 9b6h:A, 9b6h:C, 9b6h:D, 9b6k:A, 9b6k:B, 9b6k:C, 9b6k:D, 7wrb:A, 7wrb:B, 7wrb:C, 7wrb:D, 7wrc:A, 7wrc:B, 7wrc:C, 7wrc:D, 7wrd:A, 7wrd:B, 7wrd:C, 7wrd:D, 7wre:A, 7wre:B, 7wre:C, 7wre:D, 7wrf:A, 7wrf:B, 7wrf:C, 7wrf:D
83 1hiz:A 375 53 0.0582 0.0587 0.4151 4.3 3mmd:A, 4prw:A, 4pud:A, 4pue:A, 1r85:A, 1r86:A, 1r87:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218