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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MDKKYSIGLAIGTNSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRIC
YLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAH
MIKFRGHFLIEGDLNPDNVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLI
ALSLGLTPNFKSNFDLAEDTKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNTEITKAPLSASMI
KLYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLVKLNREDLLRKQ
RTFDNGIIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEKVV
DKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGDQKKAIVDLLFKTNRKVTVK
QLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHL
FDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFIQLIHDDSLTFKEDIQKAQDSLHEHIANL
AGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARNSRERMKRIEEGIKELGSQILKEHPNTQLQNEKLYLYYLQNG
RDMYVDQELDINRLSDYDVDAIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDN
LTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREIN
NYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDGKATAKYFFYSNIMNFFKTEITKRPLIETNGETGEIVWDKGRDFATV
RKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKEL
LGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLPKYSLFELENGRKRMLASAGVLQKGNELALPSKYVNFLYLASHNE
QKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIDR
KRYTSTKEVLDATLIHQSITGLYETRIDLSQL

The query sequence (length=1312) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5y36:A 1368 1365 0.9947 0.9539 0.9560 0.0 5f9r:B, 6ifo:A, 6ifo:B, 6mcb:A, 6mcc:A, 7s36:P, 7s38:P, 7s4x:A, 7v59:B, 7v59:E, 5vw1:A, 5vzl:A, 8ye6:A, 8ye9:A, 7z4c:B, 7z4e:B, 7z4k:B, 4zt0:A
2 7z4j:B 1345 1344 0.9924 0.9680 0.9688 0.0 6aeb:B, 6aeb:F, 6aeg:B, 6ai6:A, 5b2t:B, 5fw2:B, 5fw3:B, 8fzt:E, 6k4p:B, 6k4q:B, 8kah:B, 8kai:B, 8kaj:B, 8kak:B, 8kak:F, 8kal:B, 8kal:G, 8kam:B, 7ox7:B, 7ox8:B, 7ox9:B, 7oxa:B, 7qqo:B, 7qqp:B, 7qqq:B, 7qqr:B, 7qqs:B, 7qqt:B, 7qqu:B, 7qqv:B, 7qqx:B, 7qqz:B, 7qr0:B, 7qr1:B, 7qr5:B, 7qr7:B, 7qr8:B, 8wuv:A, 8ygj:A
3 5b2r:B 1319 1323 0.9848 0.9795 0.9766 0.0 5b2s:B, 5fq5:B, 5fw1:B, 8g1i:A, 6k3z:B, 6k4s:B, 6k4u:B, 6k57:B, 7qqw:B, 4un3:B, 4un4:B, 4un5:B, 8wus:A, 8wut:A, 8wuu:A
4 8kag:B 1346 1351 0.9863 0.9614 0.9578 0.0 8kah:F, 8kai:F, 8kaj:F, 8spq:A, 8sqh:A, 8srs:A, 8tzz:A, 8u3y:A, 6vpc:B, 7z4h:B, 7z4i:B, 7z4l:B, 4zt9:A
5 4oo8:A 1301 1327 0.9703 0.9785 0.9593 0.0 4zt0:C
6 8t7s:A 1312 1341 0.9604 0.9604 0.9396 0.0
7 5xbl:A 1320 1355 0.9634 0.9576 0.9328 0.0
8 6o0z:A 1288 1331 0.9527 0.9705 0.9391 0.0
9 8t6x:A 1278 1345 0.9200 0.9444 0.8974 0.0
10 4cmq:B 1168 1328 0.8605 0.9666 0.8502 0.0 4cmp:B, 4cmq:A
11 6o0y:A 1146 1026 0.7195 0.8237 0.9201 0.0
12 6o0y:A 1146 172 0.1303 0.1492 0.9942 1.47e-104
13 7z4d:B 1259 761 0.5716 0.5957 0.9855 0.0
14 7z4d:B 1259 529 0.3506 0.3654 0.8696 0.0
15 7z4g:B 1188 759 0.5716 0.6313 0.9881 0.0 7zo1:B
16 7z4g:B 1188 456 0.3171 0.3502 0.9123 0.0 7zo1:B
17 4oo8:D 1163 794 0.5770 0.6509 0.9534 0.0
18 4oo8:D 1163 419 0.3026 0.3414 0.9475 0.0
19 7s4v:A 1122 793 0.5739 0.6711 0.9496 0.0 6o0x:A, 8t6p:A
20 7s4v:A 1122 419 0.2713 0.3173 0.8496 0.0 6o0x:A, 8t6p:A
21 8t6y:A 1148 757 0.5625 0.6429 0.9749 0.0 8t6o:A, 8t79:A
22 8t6y:A 1148 416 0.2873 0.3284 0.9062 0.0 8t6o:A, 8t79:A
23 8t6t:A 1168 793 0.5625 0.6318 0.9306 0.0 8t7s:G
24 8t6t:A 1168 431 0.3056 0.3433 0.9304 0.0 8t7s:G
25 4zt9:C 1160 764 0.5473 0.6190 0.9398 0.0
26 4zt9:C 1160 496 0.3209 0.3629 0.8488 0.0
27 8t76:A 1088 757 0.5434 0.6553 0.9419 0.0
28 8t76:A 1088 416 0.2607 0.3143 0.8221 0.0
29 7s4u:A 1092 767 0.5457 0.6557 0.9335 0.0
30 7s4u:A 1092 418 0.2721 0.3269 0.8541 0.0
31 7z4d:E 1166 758 0.5274 0.5935 0.9129 0.0
32 7z4d:E 1166 520 0.3308 0.3722 0.8346 0.0
33 7s37:P 1033 659 0.4352 0.5528 0.8665 0.0 7s3h:P
34 7s37:P 1033 445 0.3110 0.3950 0.9169 0.0 7s3h:P
35 8t6s:A 962 752 0.4192 0.5717 0.7314 0.0
36 8t6s:A 962 427 0.2561 0.3493 0.7869 0.0
37 8t77:A 1025 538 0.3483 0.4459 0.8494 0.0
38 8t77:A 1025 422 0.2492 0.3190 0.7749 0.0
39 8t77:A 1025 225 0.1669 0.2137 0.9733 1.70e-125
40 8t78:A 863 422 0.2492 0.3789 0.7749 0.0
41 8t78:A 863 218 0.1608 0.2445 0.9679 1.47e-136
42 8t78:A 863 214 0.1395 0.2121 0.8551 1.22e-100
43 8t78:A 863 179 0.0899 0.1367 0.6592 6.02e-58
44 8pj9:A 1051 461 0.2134 0.2664 0.6074 0.0
45 8pj9:A 1051 449 0.1608 0.2008 0.4699 1.49e-105
46 8pj9:A 1051 173 0.0991 0.1237 0.7514 7.24e-65
47 7vw3:A 1052 466 0.0960 0.1198 0.2704 2.88e-22 5axw:A, 5czz:A, 7el1:A, 7eni:A, 7enr:A, 8jft:A, 8jg9:A, 8jg9:D
48 8jtr:A 1056 552 0.1120 0.1392 0.2663 4.31e-22
49 8jtr:A 1056 18 0.0091 0.0114 0.6667 3.2
50 8jtj:A 1042 553 0.1059 0.1334 0.2514 1.58e-17
51 8jtj:A 1042 18 0.0091 0.0115 0.6667 3.2
52 6je4:O 1049 321 0.0686 0.0858 0.2804 1.13e-15 8hj4:A, 8ja0:A, 6je9:C
53 6je4:O 1049 25 0.0107 0.0133 0.5600 6.5 8hj4:A, 8ja0:A, 6je9:C
54 6kc7:A 963 305 0.0648 0.0883 0.2787 2.26e-15
55 8hnt:A 1000 314 0.0640 0.0840 0.2675 1.04e-14
56 6jdq:A 1069 277 0.0602 0.0739 0.2852 1.30e-14 6je4:A, 6je4:E, 6je4:K, 6je9:A
57 6m0w:A 1032 611 0.1166 0.1483 0.2504 1.24e-13 6m0v:A, 6m0x:A
58 6jdv:A 1036 277 0.0595 0.0753 0.2816 2.25e-12 6kc8:A
59 8wr4:B 1442 232 0.0465 0.0423 0.2629 6.45e-06
60 8wr4:B 1442 211 0.0450 0.0409 0.2796 0.001
61 8x5v:A 892 308 0.0587 0.0863 0.2500 1.34e-05
62 8uza:A 910 315 0.0564 0.0813 0.2349 4.91e-05 8uzb:A
63 8uza:A 910 18 0.0099 0.0143 0.7222 0.53 8uzb:A
64 8wmm:B 1212 211 0.0450 0.0487 0.2796 0.001 8iyq:A, 8wmh:A, 8wmm:A, 8wmn:A, 8wmn:B, 8wr4:A
65 6rj9:C 836 370 0.0686 0.1077 0.2432 1.3 6rjd:C
66 4gyi:A 339 116 0.0221 0.0855 0.2500 1.7
67 8ewy:A 1049 51 0.0168 0.0210 0.4314 2.0 6aah:A, 6aah:B, 6bbu:A, 6c7y:A, 6dbn:A, 5e1e:A, 5e1e:B, 4e4l:A, 4e4l:E, 4e4l:B, 4e4l:D, 4e4n:A, 4e4n:B, 4e5w:A, 4e5w:B, 4ehz:A, 4ehz:B, 4ehz:C, 4ehz:D, 4ei4:A, 4ei4:B, 6elr:A, 6elr:B, 8ewy:B, 3eyg:A, 3eyh:A, 4fk6:A, 4fk6:B, 6ggh:A, 6ggh:B, 5hx8:A, 5hx8:B, 6hzu:A, 6hzu:B, 4i5c:A, 4i5c:B, 4ivb:A, 4ivb:B, 4ivc:A, 4ivc:B, 4ivd:A, 4ivd:B, 4k6z:A, 4k77:A, 4k77:B, 5khw:A, 5khw:B, 5khx:A, 6n77:A, 6n77:B, 6n78:A, 6n79:A, 6n7a:A, 6n7a:B, 6n7b:A, 6n7c:A, 6n7c:B, 6n7d:A, 6rsb:A, 6rsb:B, 6rsc:A, 6rsc:B, 6rsd:A, 6rsd:B, 6rse:A, 6rse:B, 6rsh:A, 6rsh:B, 6sm8:A, 6sm8:B, 6smb:A, 6smb:B, 7t6f:A, 7t6f:B, 6tpe:A, 6tpe:B, 6tpf:A, 6tpf:B, 6w8l:A, 5wo4:A, 5wo4:B
68 7zjm:A 220 76 0.0191 0.1136 0.3289 2.1 6atg:B, 6atg:C
69 3x1l:D 331 126 0.0244 0.0967 0.2540 2.4 3x1l:C, 3x1l:E
70 6bn2:A 393 72 0.0206 0.0687 0.3750 2.9
71 6rja:C 815 363 0.0633 0.1018 0.2287 2.9 6rja:F, 6rjg:C
72 6ly5:G 214 90 0.0206 0.1262 0.3000 3.5 6l4t:8, 6l4u:8
73 7y5e:1N 174 61 0.0160 0.1207 0.3443 4.7 7y5e:12, 7y7a:17, 7y7a:1o
74 2pla:A 343 89 0.0183 0.0700 0.2697 5.0 2pla:B
75 8ch6:P 330 50 0.0130 0.0515 0.3400 5.0 8i0t:L, 7qtt:P
76 8hnv:A 745 25 0.0107 0.0188 0.5600 5.1
77 6stt:A 178 101 0.0206 0.1517 0.2673 5.6 6stt:B
78 4j2o:C 316 53 0.0130 0.0538 0.3208 6.0 4j2o:A, 4j2o:B, 4j2o:D, 4j2o:E, 4j2o:F
79 8i0u:L 387 50 0.0130 0.0439 0.3400 6.1 8i0v:L
80 6jfu:A 884 25 0.0107 0.0158 0.5600 6.6
81 6je3:A 858 25 0.0107 0.0163 0.5600 6.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218