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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MDEELYTLIEFLKKPSISATGEGIDETANYLKETVEKLLGVKANLEKTKGHPVVYAEINVNAKKTLLIYNHYDVQPVDPI
SEWKRAPFSATIENDRIYARGASDNKGTLMARLFAIKHLLDKNELNVNVKLLYEGEEEIGSVNLEDYIEKNTNKLKADSV
IMEGAGLDPKGRPQIVLGVKGLLYVELVLDYGTKDLHSSNAPLVRNPCIDLAKIISTLVDMGGRVLIEGFYDDVRELTEE
ERELIKKYDIDVEELKKALGFKELKYNEKEKIAEALLTYPTCNVDGFECGYTGKGSKTIVPHRAFAKLDFRLVPNQDPYK
VFELLKKHLQKAGFNGEILAHGFEYPVRTSVNSTVVKAMIESAKKVYGTEPQVIPNSAGTQPMGLFVYKLGIRDAVSAIG
AGGYYSNAHAPNENIKIDDYYKAIKHTEEFLKLYPIL

The query sequence (length=437) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4mmo:A 437 437 1.0000 1.0000 1.0000 0.0
2 2pok:A 458 440 0.3455 0.3297 0.3432 9.36e-70 2pok:B
3 4g1p:A 479 398 0.2723 0.2484 0.2990 2.60e-49
4 3dlj:A 471 392 0.2632 0.2442 0.2934 1.60e-46 3dlj:B
5 2zof:A 478 392 0.2563 0.2343 0.2857 2.03e-42 4ruh:A, 4ruh:B, 2zof:B, 2zog:A, 2zog:B
6 3pfe:A 471 450 0.2380 0.2208 0.2311 6.07e-13
7 4h2k:A 258 124 0.0824 0.1395 0.2903 2.08e-07 4h2k:B
8 5vo3:A 380 124 0.0824 0.0947 0.2903 4.13e-07 3ic1:A, 3ic1:B, 3isz:A, 3isz:B
9 4op4:B 265 74 0.0481 0.0792 0.2838 2.53e-06 4op4:A
10 7uoi:A 383 70 0.0641 0.0731 0.4000 4.60e-06 8vkt:A
11 8uw6:B 381 170 0.1007 0.1155 0.2588 1.30e-05 7rsf:A, 7rsf:B, 8uw6:A, 8uw6:C, 8uw6:D
12 1cg2:A 389 216 0.1327 0.1491 0.2685 3.15e-05 1cg2:B, 1cg2:C, 1cg2:D, 6xj5:A, 6xj5:B, 6xj5:C, 6xj5:D, 6xj5:E, 6xj5:F, 6xj5:G, 6xj5:H
13 3pfo:A 426 85 0.0572 0.0587 0.2941 6.06e-05 3pfo:B
14 7lgp:B 377 119 0.0686 0.0796 0.2521 6.73e-05 7lgp:A
15 7lgp:B 377 131 0.0618 0.0716 0.2061 8.2 7lgp:A
16 7t1q:A 377 162 0.1053 0.1220 0.2840 1.16e-04 8f8o:A, 8f8o:B, 7t1q:B
17 4o23:A 376 74 0.0481 0.0559 0.2838 1.75e-04 4o23:B, 4ppz:A, 4pqa:A, 5uej:A, 5uej:B
18 5xoy:A 341 179 0.1076 0.1378 0.2626 2.75e-04
19 7m6u:B 392 169 0.1076 0.1199 0.2781 0.001 7m6u:A, 7m6u:C, 7m6u:D
20 3ki9:A 467 124 0.0801 0.0749 0.2823 0.001
21 1q7l:A 192 105 0.0664 0.1510 0.2762 0.003 1q7l:C
22 1lfw:A 468 63 0.0526 0.0491 0.3651 0.009
23 2q6v:A 370 138 0.0686 0.0811 0.2174 0.49 3cv3:A
24 3grr:A 263 126 0.0801 0.1331 0.2778 1.7 3gru:A, 3grv:A, 3gry:A
25 4rpu:A 988 53 0.0343 0.0152 0.2830 2.8 4l3t:A, 4l3t:B, 4nge:A, 4nge:D, 4rpu:B
26 6xov:A 966 53 0.0343 0.0155 0.2830 2.8
27 7mq8:LJ 469 77 0.0481 0.0448 0.2727 3.7 7mq9:LJ, 7mqa:LJ
28 1w6u:A 288 43 0.0366 0.0556 0.3721 3.8 1w6u:B, 1w6u:C, 1w6u:D, 1w73:A, 1w73:B, 1w73:C, 1w73:D, 1w8d:A, 1w8d:B, 1w8d:C, 1w8d:D
29 6iu4:A 225 122 0.0686 0.1333 0.2459 4.4 6iu3:A, 6iu5:A, 6iu5:D, 6iu5:B, 6iu5:C, 6iu5:E, 6iu5:H, 6iu5:F, 6iu5:I, 6iu6:A, 6iu6:D, 6iu6:B, 6iu6:C, 6iu6:E, 6iu6:H, 6iu6:F, 6iu6:I, 6iu8:A, 6iu8:B, 6iu8:C, 6iu8:D, 6iu8:E, 6iu8:F, 6iu8:H, 6iu8:I, 6iu9:A, 6iu9:D, 6iu9:B, 6iu9:C, 6iu9:E, 6iu9:H, 6iu9:F, 6iu9:I
30 4fns:A 718 83 0.0526 0.0320 0.2771 5.0 4fns:B, 4fns:C, 4fns:D, 4fnt:C, 4fnt:B, 4fnt:A, 4fnt:D, 4fnu:A, 4fnu:B, 4fnu:C, 4fnu:D
31 3oyz:A 376 121 0.0686 0.0798 0.2479 6.0
32 5tao:A 356 121 0.0686 0.0843 0.2479 7.0 3oyx:A, 3pug:A
33 8fvu:A 1361 51 0.0366 0.0118 0.3137 8.5 2vm5:A
34 8rdj:D 611 48 0.0320 0.0229 0.2917 9.3 8ras:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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