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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLE
YSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGK
KMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLN
QQDVPDKFKYKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYLG

The query sequence (length=290) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3ecs:C 294 296 0.9862 0.9728 0.9662 0.0 3ecs:B, 3ecs:D, 3ecs:E, 3ecs:F, 3ecs:G, 3ecs:H, 7kma:A, 7kma:C, 7kma:D, 7kma:E, 7kma:F, 7kma:G, 7kma:H, 7kmf:H, 7kmf:G
2 7kma:B 268 289 0.9172 0.9925 0.9204 0.0
3 6o85:E 357 202 0.2172 0.1765 0.3119 2.93e-26
4 5yfj:A 322 240 0.2207 0.1988 0.2667 2.31e-25 5yfj:B, 5yfj:C, 5yfs:A, 5yfs:B, 5yfs:C, 5yft:A, 5yft:B, 5yft:C, 5yfu:A, 5yfu:B, 5yfu:C, 5yfv:A, 5yfv:B, 5yfv:C, 5yfw:A, 5yfw:B, 5yfw:C, 5yfx:A, 5yg5:A, 5yg5:B, 5yg5:C, 5yg6:A, 5yg6:C, 5yg6:B, 5yg7:A, 5yg7:C, 5yg7:B, 5yg8:A, 5yg8:B, 5yg8:C, 5yg9:A, 5yg9:B, 5yg9:C, 5yga:A, 5yga:B, 5yga:C
5 3a9c:B 325 214 0.2172 0.1938 0.2944 3.12e-25 3a9c:A, 3a9c:C, 3a9c:D, 3a9c:E, 3a9c:F, 3vm6:A, 3vm6:B, 3vm6:C
6 6caj:C 318 242 0.2483 0.2264 0.2975 2.89e-22 6caj:D, 6ezo:C, 6ezo:D, 7l7g:C, 7l7g:D, 6o81:C, 6o81:D, 6o85:C, 6o85:D
7 6jly:G 363 253 0.2310 0.1846 0.2648 2.03e-17
8 6jly:C 338 173 0.1828 0.1568 0.3064 5.63e-16 6jly:D, 6jlz:C, 6jlz:D
9 2yvk:A 349 269 0.2276 0.1891 0.2454 1.03e-09 2yrf:A, 2yrf:B, 2yvk:B, 2yvk:C, 2yvk:D
10 3fa3:B 302 54 0.0793 0.0762 0.4259 0.13 3fa3:A, 3fa3:C, 3fa3:D, 3fa3:E, 3fa3:F, 3fa3:G, 3fa3:H, 3fa3:I, 3fa3:J, 3fa3:K, 3fa3:L, 3fa3:M, 3fa3:N, 3fa3:O, 3fa3:P, 3fa4:A, 3fa4:B, 3fa4:C, 3fa4:D, 3fa4:E, 3fa4:F, 3fa4:G, 3fa4:H, 3fa4:I, 3fa4:J, 3fa4:K, 3fa4:L
11 1h31:A 261 126 0.0931 0.1034 0.2143 0.28 1h31:C, 1h31:E, 1h31:G, 1h32:A, 1h33:A, 2oz1:A, 2oz1:C, 2oz1:E, 2oz1:G
12 6pcm:A 793 33 0.0517 0.0189 0.4545 1.3 6pcm:B
13 2z09:A 124 97 0.1069 0.2500 0.3196 1.4 2z08:A
14 8il4:C 619 113 0.0931 0.0436 0.2389 1.6 8il4:A, 8il4:B, 8il4:D
15 5koi:A 271 39 0.0552 0.0590 0.4103 1.8 5koi:B, 5koi:C, 5koi:D, 5koi:E, 5koi:F, 5koi:G, 5koi:H
16 1rzl:A 91 46 0.0586 0.1868 0.3696 3.8 1uvc:A, 1uvc:B
17 8p82:A 1596 35 0.0414 0.0075 0.3429 4.9 8p82:B
18 8bh7:r 71 43 0.0414 0.1690 0.2791 7.6 7aso:9, 7asp:i, 7bgd:r, 8bh6:r, 8byv:r, 6fxc:Ar, 6fxc:Br, 7kwg:r, 5li0:r, 5nd8:r, 5nd9:r, 5ngm:Ar, 7nhl:s, 7nhm:s, 8p2f:s, 8p2g:s, 8p2h:s, 7p48:r, 6s0x:r, 6s13:r, 5t7v:S9, 5tcu:S9, 8y38:r, 8y39:r, 6yef:r
19 1v9n:A 348 27 0.0414 0.0345 0.4444 7.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218