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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDA
SKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVA
KVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATG
SLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSY
TAQLVRTLAYLAE

The query sequence (length=333) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3lvf:P 338 333 1.0000 0.9852 1.0000 0.0 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
2 5vmt:B 334 332 0.6997 0.6976 0.7018 2.81e-175 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
3 5m6d:A 346 331 0.6967 0.6705 0.7009 3.18e-171 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
4 5utm:A 345 334 0.6907 0.6667 0.6886 8.95e-168 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
5 6fzi:B 332 329 0.6937 0.6958 0.7021 3.29e-165 6fzi:A, 6fzi:C, 6fzi:D
6 5ld5:C 342 336 0.6426 0.6257 0.6369 5.74e-149 5ld5:A, 5ld5:B, 5ld5:D
7 5vmt:E 293 326 0.6366 0.7235 0.6503 7.10e-148
8 7www:A 336 335 0.5826 0.5774 0.5791 3.98e-135
9 8hmn:D 340 339 0.5946 0.5824 0.5841 2.74e-134 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
10 7c5o:O 338 333 0.5826 0.5740 0.5826 2.98e-134 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
11 7jwk:C 333 332 0.5375 0.5375 0.5392 1.75e-126 7jwk:A, 7jwk:B, 7jwk:D
12 1hdg:O 332 334 0.5405 0.5422 0.5389 1.85e-125 1hdg:Q
13 2ep7:B 339 344 0.5285 0.5192 0.5116 5.18e-117 2ep7:A
14 8hrq:B 336 330 0.5435 0.5387 0.5485 8.31e-111 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
15 4p8r:A 331 337 0.4985 0.5015 0.4926 1.47e-108 4p8r:B, 4p8r:C, 4p8r:D
16 3hja:A 334 333 0.5015 0.5000 0.5015 2.22e-108 3hja:B, 3hja:C, 3hja:D
17 6ok4:A 334 336 0.4895 0.4880 0.4851 3.11e-108 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
18 3cmc:O 334 336 0.5135 0.5120 0.5089 4.69e-107 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
19 8br4:A 339 336 0.5195 0.5103 0.5149 1.15e-105 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
20 3doc:A 335 339 0.4895 0.4866 0.4808 1.96e-103 3doc:B, 3doc:C, 3doc:D
21 4mvj:B 332 337 0.4775 0.4789 0.4718 7.91e-103 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
22 3l0d:A 332 339 0.4805 0.4819 0.4720 1.06e-100 3l0d:B
23 1cer:O 331 323 0.4985 0.5015 0.5139 1.30e-100 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
24 4lsm:A 331 334 0.4685 0.4713 0.4671 2.29e-100 4lsm:B
25 6nlx:C 335 329 0.4835 0.4806 0.4894 4.08e-100 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
26 8oha:B 336 336 0.4835 0.4792 0.4792 1.99e-99 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
27 3gnq:C 335 339 0.4955 0.4925 0.4867 8.03e-99 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
28 8de5:A 338 339 0.4745 0.4675 0.4661 4.06e-97
29 3cif:A 338 336 0.4625 0.4556 0.4583 3.82e-95 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
30 1ywg:O 337 332 0.4595 0.4540 0.4608 1.49e-94 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
31 7xzg:A 334 337 0.4595 0.4581 0.4540 2.30e-94 7xzg:B, 7xzg:C, 7xzg:D
32 3pym:A 332 336 0.4565 0.4578 0.4524 2.57e-94 3pym:B
33 6m5x:O 334 335 0.4595 0.4581 0.4567 9.65e-94 6m5x:R, 6m5x:P, 6m5x:Q
34 1obf:O 335 337 0.4685 0.4657 0.4629 2.18e-93 1obf:P
35 1dss:G 333 333 0.4655 0.4655 0.4655 7.61e-93 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
36 7bew:A 330 336 0.4625 0.4667 0.4583 1.72e-92 7bex:A
37 6px2:A 332 336 0.4715 0.4729 0.4673 3.60e-92 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
38 6m61:O 336 336 0.4505 0.4464 0.4464 7.34e-92 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
39 6ghr:B 342 338 0.4835 0.4708 0.4763 1.04e-91 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
40 2vyn:D 334 335 0.4505 0.4491 0.4478 8.29e-91 2vyv:D
41 3sth:C 340 339 0.4505 0.4412 0.4425 3.68e-90 3sth:A, 3sth:B, 3sth:D
42 3gpd:R 334 334 0.4474 0.4461 0.4461 1.81e-89 3gpd:G
43 6qun:O 334 338 0.4474 0.4461 0.4408 3.69e-88 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
44 4k9d:A 338 340 0.4595 0.4527 0.4500 6.32e-88 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
45 3h9e:P 337 333 0.4444 0.4392 0.4444 9.05e-88 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
46 3b1j:A 338 340 0.4925 0.4852 0.4824 6.08e-86 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
47 3e5r:O 336 338 0.4354 0.4315 0.4290 1.30e-85 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
48 2i5p:O 309 335 0.4354 0.4693 0.4328 3.21e-85 2i5p:P
49 1nbo:O 337 330 0.4565 0.4510 0.4606 5.53e-84 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
50 1a7k:A 358 352 0.4565 0.4246 0.4318 1.27e-83 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
51 3dmt:A 359 355 0.4474 0.4150 0.4197 2.39e-82 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
52 7q54:C 368 332 0.4655 0.4212 0.4669 1.51e-79 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
53 7zq3:R 348 331 0.4685 0.4483 0.4713 3.88e-77 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
54 9iil:A 341 340 0.4054 0.3959 0.3971 1.37e-76 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
55 3k2b:A 337 330 0.4384 0.4332 0.4424 1.19e-74 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
56 2xf8:M 327 338 0.3874 0.3945 0.3817 1.22e-69 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
57 8jb1:A 468 347 0.3664 0.2607 0.3516 3.37e-57 8jb1:B
58 8i7h:A 297 30 0.0420 0.0471 0.4667 0.22 8i7h:B, 8i7h:C, 8i7h:D
59 3ec7:A 336 48 0.0631 0.0625 0.4375 0.87 3ec7:B, 3ec7:C, 3ec7:D, 3ec7:E, 3ec7:F, 3ec7:G, 3ec7:H
60 1cf2:P 336 170 0.1261 0.1250 0.2471 0.94 1cf2:R, 1cf2:O, 1cf2:Q
61 3tz6:A 342 38 0.0390 0.0380 0.3421 1.4 3vos:A
62 3hsk:A 358 129 0.0931 0.0866 0.2403 2.2
63 3aoe:B 424 59 0.0601 0.0472 0.3390 2.2 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
64 5j5d:A 297 55 0.0571 0.0640 0.3455 2.7 3l21:B, 1xxx:A, 1xxx:B, 1xxx:C, 1xxx:D, 1xxx:E, 1xxx:F, 1xxx:G, 1xxx:H
65 4ztx:A 768 48 0.0420 0.0182 0.2917 3.0
66 8hi5:A 647 75 0.0601 0.0309 0.2667 3.5
67 4kpn:A 318 84 0.0601 0.0629 0.2381 4.3 4kpn:B, 4kpn:C, 4kpn:D, 4kpn:E, 4kpn:F, 4kpn:G, 4kpn:H
68 4min:A 339 36 0.0511 0.0501 0.4722 5.1 4min:B, 4min:C, 4min:D, 4mio:A, 4mio:B, 4mio:C, 4mio:D, 4miy:A, 4miy:B, 4miy:C, 4miy:D, 4mjl:A, 4mjl:B, 4mjl:C, 4mjl:D
69 8brm:LB 378 134 0.0931 0.0820 0.2313 6.1 8br8:LB, 8bsi:LB, 8bsj:LB, 8btd:LB, 8btr:LB, 8fru:B, 7pwg:B, 7pwo:B2
70 3fcr:A 458 49 0.0571 0.0415 0.3878 9.0
71 2ux8:G 288 70 0.0661 0.0764 0.3143 9.5 2ux8:B, 2ux8:C, 2ux8:D, 2ux8:E, 2ux8:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218