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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MATRIAILGAGPSGMAQLRAFQSAQEKGAEIPELVCFEKQADWGGQWNYTWRTGLDENGEPVHSSMYRYLWSNGPKECLE
FADYTFDEHFGKPIPSYPPREVLWDYIKGRVEKAGVRKYIRFNTAVRHVEFNEDTQTFTVTVQDHTTDTIYSEEFDYVVC
CTGHFSTPYVPEFEGFEKFGGRILHAHDFRDALEFKGKTVLLVGSSYSAEDIGSQCYKYGAKKVISCYRTAPMGYDWPEN
WDERPNLVRVDGENAYFADGSSEKVDAIILCTGYIHHFPFLNDDLRLVTDNRLWPPNLYKGVVWEDNPKFFYIGMQDQWY
SFNMFDAQAWYARDVIMGRIPLPSKEEMKADSQAWREREETLKTDEEMYDFQGDYIQDLIDMTDYPSFDIPAVNKTFKEW
KHHKKENIMTFRDHSYRSLMTGTMAPKHHTPWIDALDDSLEAFLSDKS

The query sequence (length=448) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xlr:C 452 448 0.9487 0.9403 0.9487 0.0 8b2d:A, 8b2d:B, 2vq7:A, 2vq7:B, 2vq7:C, 2vq7:D, 2vqb:A, 2vqb:B, 2vqb:C, 2vqb:D, 2xlp:A, 2xlp:B, 2xlp:C, 2xlp:D, 2xlr:A, 2xlr:B, 2xlr:D, 2xls:A, 2xls:B, 2xls:C, 2xls:D, 2xlt:A, 2xlt:B, 2xlt:C, 2xlt:D, 2xlu:A, 2xlu:B, 2xlu:C, 2xlu:D, 2xve:B, 2xve:C, 2xvf:A, 2xvf:B, 2xvf:C, 2xvh:A, 2xvh:B, 2xvh:C, 2xvi:A, 2xvi:B, 2xvi:C, 2xvj:A, 2xvj:B, 2xvj:C
2 6hns:A 443 442 0.7500 0.7585 0.7602 0.0 6hns:B
3 5gsn:A 445 442 0.6473 0.6517 0.6561 0.0 5gsn:B, 5gsn:C, 5gsn:D, 5ipy:A, 5ipy:B, 5iq1:A, 5iq1:B, 5iq4:A, 5iq4:B
4 7d4k:A 444 445 0.5558 0.5608 0.5596 0.0 7d4k:B, 7d4m:A, 7d4m:B, 7d4n:A, 7d4n:B
5 6kbw:A 446 444 0.5558 0.5583 0.5608 0.0 6kbw:B
6 5nmx:D 409 426 0.3214 0.3521 0.3380 6.73e-63 5nmw:A, 5nmw:B, 5nmw:C, 5nmw:D, 5nmx:A, 5nmx:B, 5nmx:C
7 6wpu:A 439 375 0.2634 0.2688 0.3147 1.12e-39
8 2gv8:A 442 424 0.2522 0.2557 0.2665 2.22e-32 2gv8:B, 2gvc:A, 2gvc:B, 2gvc:D, 2gvc:E, 1vqw:A, 1vqw:B
9 6se3:D 528 234 0.1741 0.1477 0.3333 1.24e-26 6se3:A, 6se3:B, 6se3:C, 6se3:E, 6se3:F
10 6se3:D 528 145 0.0960 0.0814 0.2966 1.60e-07 6se3:A, 6se3:B, 6se3:C, 6se3:E, 6se3:F
11 6sem:B 530 245 0.1719 0.1453 0.3143 7.04e-26 6sem:A, 6sem:C, 6sem:D, 6sf0:B, 6sf0:A, 6sf0:C, 6sf0:D
12 6sem:B 530 131 0.0938 0.0792 0.3206 9.39e-08 6sem:A, 6sem:C, 6sem:D, 6sf0:B, 6sf0:A, 6sf0:C, 6sf0:D
13 7al4:D 524 231 0.1719 0.1469 0.3333 8.04e-24 7al4:C, 7al4:B, 7al4:A
14 7al4:D 524 146 0.0826 0.0706 0.2534 0.006 7al4:C, 7al4:B, 7al4:A
15 6sek:A 504 234 0.1585 0.1409 0.3034 1.09e-20 6sek:B
16 6sek:A 504 166 0.1183 0.1052 0.3193 1.72e-12 6sek:B
17 8odw:A 612 214 0.1183 0.0866 0.2477 1.88e-12 8odw:B
18 6jdk:B 516 229 0.1228 0.1066 0.2402 8.10e-10 6jdk:A
19 1w4x:A 533 225 0.1250 0.1051 0.2489 3.59e-09 4c74:A, 4c77:A, 4d03:A, 4d04:A, 4ovi:A, 2ylr:A, 2yls:A, 2ylt:A, 2ylw:A, 2ylx:A, 2ylz:A, 2ym1:A, 2ym2:A
20 7v4x:A 529 206 0.1116 0.0945 0.2427 2.55e-08 6a37:A, 7v50:A, 7v51:A
21 6gqi:A 529 216 0.1205 0.1021 0.2500 3.71e-08 6gqi:B, 5m0z:A, 5m10:A, 7v8o:A, 7v8o:B, 7v8r:A, 7v8s:A, 7v8s:B
22 4aos:A 523 209 0.1049 0.0899 0.2249 4.66e-06 4aox:A, 4ap1:A, 4ap3:A
23 4usr:A 357 55 0.0446 0.0560 0.3636 6.69e-06
24 3uoz:A 540 214 0.1116 0.0926 0.2336 7.07e-06 3uov:A, 3uov:B, 3uox:A, 3uox:B, 3uoy:A, 3uoy:B, 3uoz:B, 3up4:A, 3up4:B, 3up5:A, 3up5:B
25 5j7x:A 527 209 0.1138 0.0968 0.2440 9.57e-06
26 6er9:A 531 207 0.1049 0.0885 0.2271 1.69e-05 6er9:B, 6era:A, 6era:B, 3gwd:A, 3gwf:A, 4rg3:A, 4rg4:A, 3ucl:A
27 4c5o:D 333 156 0.0893 0.1201 0.2564 2.49e-05 4a9w:A, 4a9w:B, 4c5o:A, 4c5o:B, 4c5o:C, 4c5o:E, 4c5o:F, 4c5o:G, 4c5o:H
28 4usq:F 341 187 0.0848 0.1114 0.2032 5.76e-05 4usq:A
29 2cdu:A 451 96 0.0625 0.0621 0.2917 8.92e-05 2cdu:B
30 7a76:A 326 228 0.1339 0.1840 0.2632 3.95e-04 7a76:B, 7a76:C, 7a76:D
31 6y48:B 538 210 0.1004 0.0836 0.2143 6.11e-04 6y48:A, 6y48:C, 6y48:D
32 5mq6:A 636 131 0.0647 0.0456 0.2214 0.001
33 8acs:A 598 99 0.0580 0.0435 0.2626 0.005 8acs:B, 8acs:C, 8acs:D
34 8c3m:A 346 160 0.1004 0.1301 0.2812 0.034 8c3m:B, 6gar:A, 6gar:B
35 6ruz:A 443 54 0.0402 0.0406 0.3333 0.040 6ruz:B, 6ruz:C, 6ruz:D, 6rvb:A, 6rvb:B, 6rvb:C, 6rvb:D, 6rvh:A, 6rvh:B, 6rvh:C, 6rvh:D
36 3ict:A 557 62 0.0424 0.0341 0.3065 0.13 3icr:A, 3icr:B, 3ics:A, 3ics:B, 3ict:B
37 4ien:A 154 35 0.0335 0.0974 0.4286 1.4 4ien:B, 4ien:C, 4ien:D, 5szu:A, 5szu:B, 5szu:D, 5szv:A, 5szv:B, 5szv:C, 5szv:D, 5szy:A, 5szy:B, 5szy:D, 5szy:C, 5szz:A, 5szz:B, 5szz:D, 5szz:C, 5t02:A, 5t02:B, 5t02:C, 5t02:D, 5t02:E, 5t02:F, 5v3a:A, 5v3a:B, 5v3a:C, 5v3a:D
38 5ygq:A 341 55 0.0424 0.0557 0.3455 1.6 5ygq:B
39 5ode:A 324 150 0.0826 0.1142 0.2467 2.5 5n0j:A, 5n0j:B, 5ode:B
40 2bhr:B 439 36 0.0357 0.0364 0.4444 2.6 2bhr:A
41 1a0d:A 437 129 0.0692 0.0709 0.2403 3.8 1a0d:B, 1a0d:C, 1a0d:D
42 5er0:A 450 87 0.0603 0.0600 0.3103 3.9 5er0:B, 5er0:C, 5er0:D, 5vn0:A, 5vn0:B, 5vn0:C, 5vn0:D, 5vn0:E, 5vn0:F, 5vn0:G, 5vn0:H, 5voh:A, 5voh:B, 5voh:C, 5voh:D
43 4kcf:A 407 69 0.0424 0.0467 0.2754 4.4 3m9v:A
44 6wmr:Z 470 82 0.0580 0.0553 0.3171 5.1 6wmt:Z
45 6du7:A 448 135 0.0804 0.0804 0.2667 5.4 6du7:B, 6du7:C, 6du7:D, 6du7:E, 6du7:F, 6du7:G, 6du7:H
46 2zbw:B 334 113 0.0647 0.0868 0.2566 8.3 2zbw:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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