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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MAQTEKLTDYVNPFVGTDGYGNVYPGAQIPFGGIQISPDTDSRFYDAASGYKYNHLTLMGFSLTHLSGTGIPDLGDFLFI
PGTGEMKLEPGTHEDPDQGYRSRYSHDKEWASPNYYAVELADYGVKAEMTSGVRSGMFRFTYPESDNAFIMIDMNHTLWQ
SCEWSNLRMINDSTITGYKLVKGWGPERHVYFTATFSKKLTGLRFVQDKKPVIYNTSRFRSSYEAWGKNLMACISFDTKA
GEEVTVKTAISAVSTDGARNNMKELDGLTFNELRAKGEALWEKELGKYTLTADRKTKETFYTSAYHAALHPFIFQDSDGQ
FRGLDKNIEKAEGFTNYTVFSLWDTYRALHPWFNLVQQEVNADIANSMLAHYDKSVEKMLPIWSFYGNETWCMIGYHAVS
VLADMIVKEVKGFDYERAYEAMKTTAMNSNYDCLPEYREMGYVPFDKEAESVSKTLEYAYDDYCIAQAAKKLGKEDDYHY
FLNRALSYQTLIDPETKYMRGRDSKGDWRTPFTPVAYWGDITEGFTMQYTWYVPQDVQGYINEAGKELFRKRLDELFTVE
LQGRIGAYWHGNEPCHHVAYLYNYLKEPWKCQKWIRTIVDRFYGNTPDALSGNDDCGQMSAWYMFNCIGFYPVAPSSNIY
NIGSPCAEAITVRMSNGKNIEMTADNWSPKNLYVKELYVNGKKYDKSYLTYDDIRDGVKLRFVMSGKPNYKRAVSDEAVP
PSISLPEKTMKYKSSIGFLE

The query sequence (length=740) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6f92:A 760 754 0.9946 0.9684 0.9761 0.0 6f91:A, 6f91:B, 6f91:C, 6f91:D, 6f91:E, 6f91:F, 6f91:G, 6f91:H, 6f92:B, 6f92:C, 6f92:D
2 6f8z:A 715 734 0.3865 0.4000 0.3896 1.73e-175 6f8z:B, 6f8z:C, 6f90:A, 6f90:B, 6f90:C
3 7zgm:A 702 720 0.3770 0.3974 0.3875 2.16e-149
4 2wvz:B 742 763 0.3351 0.3342 0.3250 2.32e-117 2wvx:A, 2wvx:B, 2wvx:C, 2wvx:D, 2wvz:A, 2wvz:C, 2wvz:D, 2ww0:A, 2ww0:B, 2ww0:C, 2ww0:D, 2ww0:E, 2ww0:F, 2ww0:G, 2ww0:H, 2ww1:A, 2ww1:B, 2ww1:C, 2ww1:D, 2ww3:A, 2ww3:B, 2ww3:C, 2ww3:D, 2ww3:E, 2ww3:F, 2wzs:A, 2wzs:B, 2wzs:C, 2wzs:D, 2wzs:E, 2wzs:F, 2wzs:G, 2wzs:H
5 2ww2:B 737 766 0.3176 0.3189 0.3068 5.71e-108
6 7nsn:A 1371 796 0.3068 0.1656 0.2852 9.46e-72 7nsn:B
7 6dwo:A 712 720 0.2622 0.2725 0.2694 7.17e-65 6dwo:B, 6dwo:C, 6dwo:D, 7fe1:A, 7fe1:B, 7fe1:C, 7fe1:D, 7fe2:A, 7fe2:B, 7fe2:C, 7fe2:D
8 4aq0:A 765 768 0.2486 0.2405 0.2396 1.58e-47 4aq0:B, 2xsg:A, 2xsg:B
9 5swi:B 693 727 0.2459 0.2626 0.2503 3.53e-42 5swi:A, 5swi:C, 5swi:D
10 4kqp:A 230 42 0.0230 0.0739 0.4048 2.2
11 3ahc:A 802 119 0.0419 0.0387 0.2605 2.3 3ahd:A, 3ahe:A, 3ahf:A, 3ahg:A, 3ahh:A, 3ahi:A, 3ahj:A
12 8fnv:A 770 136 0.0514 0.0494 0.2794 2.5 8fnv:B, 8fnv:C, 8fnv:D, 8fnv:E, 8fnv:F, 8fnv:G, 8fnv:H, 8fnv:I, 8fnv:J, 8fnv:K, 8fnv:L, 8fnw:A, 8fnw:B, 8fnw:C, 8fnw:D, 8fnw:E, 8fnw:F, 8fnw:G, 8fnw:H, 8fnw:I, 8fnw:J, 8fnw:K, 8fnw:L
13 8tn6:A 147 28 0.0162 0.0816 0.4286 5.9 8tn6:B, 8tn6:C, 8tnb:A, 8tnb:B, 8tnb:C, 8tnc:A, 8tnc:B, 8tnc:C, 8tnd:A, 8tnd:B, 8tnd:C
14 2k16:A 75 59 0.0230 0.2267 0.2881 8.8 5c13:A, 5c13:C, 5c13:E, 5c13:G, 2k17:A, 5wxg:A, 5wxh:C, 5wxh:A, 5xmy:A, 5xmy:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218