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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MAFTNYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAAS
VIQFGKLTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAI
ETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRAYAAVL
YIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLGGDLTRD
SRVMLRQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMAC
GGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKR
RRAMEIPTTIQCDLCLKWRTLPFDTWVCSMNPDPEQDRCEASEQKQKVPLGTFR

The query sequence (length=534) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ofb:B 541 543 0.9963 0.9834 0.9797 0.0 5of9:A, 5of9:B, 5ofa:B, 5ofa:A, 5ofb:A
2 7k7t:A 390 246 0.1723 0.2359 0.3740 2.60e-44 7k7t:B
3 7k7t:A 390 210 0.1067 0.1462 0.2714 6.49e-14 7k7t:B
4 5ix1:A 414 264 0.1835 0.2367 0.3712 1.56e-42
5 5ix1:A 414 273 0.1461 0.1884 0.2857 5.93e-23
6 6o1e:A 431 277 0.1779 0.2204 0.3430 4.57e-41 5ix1:B, 5ix2:A, 5ix2:B, 4qq4:A, 4qq4:B, 5svi:A, 5svi:B, 5svx:A, 5svy:A
7 6o1e:A 431 176 0.1199 0.1485 0.3636 1.17e-26 5ix1:B, 5ix2:A, 5ix2:B, 4qq4:A, 4qq4:B, 5svi:A, 5svi:B, 5svx:A, 5svy:A
8 6o5w:A 57 45 0.0393 0.3684 0.4667 8.43e-08
9 6lzj:A 245 52 0.0337 0.0735 0.3462 0.034 6lzi:A
10 7rci:A 317 72 0.0449 0.0757 0.3333 0.12 1ea6:A, 1ea6:B, 1h7u:B, 1h7u:A, 7rci:B, 7rck:A, 7rck:B
11 2e61:A 69 46 0.0300 0.2319 0.3478 0.15 2rr4:A
12 4o62:B 57 46 0.0300 0.2807 0.3478 0.22 4o62:A, 4o62:C, 4z0o:A, 4z0r:B, 4z0r:A, 4z0r:C
13 6qxz:A 79 44 0.0243 0.1646 0.2955 0.27
14 7aib:C 267 52 0.0375 0.0749 0.3846 0.30 7aic:C
15 2l7p:A 100 44 0.0243 0.1300 0.2955 0.36 5yvx:A
16 4rul:A 823 118 0.0637 0.0413 0.2881 0.73 1cy1:A, 1cy2:A, 1cy4:A, 1cy6:A, 1cy7:A, 1cy8:A, 1mw8:X, 3px7:A
17 5jil:A 369 58 0.0243 0.0352 0.2241 0.81 4zxn:A
18 1b63:A 333 45 0.0356 0.0571 0.4222 1.1 1b62:A, 1nhh:A, 1nhi:A, 1nhj:A, 7p8v:A, 7p8v:B
19 3h4l:B 344 49 0.0375 0.0581 0.4082 2.6 3h4l:A
20 3lpa:A 340 26 0.0187 0.0294 0.3846 3.7 3lpc:A, 3lpd:A
21 4c7w:A 353 37 0.0206 0.0312 0.2973 4.6 4c7w:B
22 8grv:A 336 46 0.0262 0.0417 0.3043 4.7
23 8uu7:q 81 48 0.0356 0.2346 0.3958 6.8 7nhn:r, 8uu4:q, 8uu5:q, 8uu6:q, 8uu8:q, 8uu9:q
24 4tlx:A 415 89 0.0431 0.0554 0.2584 7.8 4tlx:B, 4tlx:C, 4tlx:D, 4tlz:A, 4tlz:B, 4tlz:C, 4tlz:D, 4tm0:A, 4tm0:B, 4tm0:C, 4tm0:D, 4tm1:A, 4tm1:B, 4tm1:C, 4tm1:D, 4tm3:A, 4tm3:B, 4tm3:C, 4tm3:D, 4tm4:A, 4tm4:B, 4tm4:C, 4tm4:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218