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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MAFTNYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAAS
VIQFGKLAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTD
NVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSF
RAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRL
GLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLE
GGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSE
LRYKRRRAMEIPTTIQCDLCLKWRTLPFYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFR

The query sequence (length=541) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ofb:B 541 541 1.0000 1.0000 1.0000 0.0 5of9:A, 5of9:B, 5ofa:B, 5ofa:A, 5ofb:A
2 7k7t:A 390 251 0.1719 0.2385 0.3705 2.36e-44 7k7t:B
3 7k7t:A 390 236 0.1146 0.1590 0.2627 3.53e-15 7k7t:B
4 5ix1:A 414 264 0.1811 0.2367 0.3712 5.44e-43
5 5ix1:A 414 185 0.1220 0.1594 0.3568 7.68e-24
6 6o1e:A 431 277 0.1756 0.2204 0.3430 2.21e-41 5ix1:B, 5ix2:A, 5ix2:B, 4qq4:A, 4qq4:B, 5svi:A, 5svi:B, 5svx:A, 5svy:A
7 6o1e:A 431 265 0.1516 0.1903 0.3094 1.08e-27 5ix1:B, 5ix2:A, 5ix2:B, 4qq4:A, 4qq4:B, 5svi:A, 5svi:B, 5svx:A, 5svy:A
8 6o5w:A 57 45 0.0407 0.3860 0.4889 6.07e-09
9 2e61:A 69 45 0.0296 0.2319 0.3556 0.005 2rr4:A
10 6lzj:A 245 52 0.0333 0.0735 0.3462 0.034 6lzi:A
11 4o62:B 57 46 0.0296 0.2807 0.3478 0.11 4o62:A, 4o62:C, 4z0o:A, 4z0r:B, 4z0r:A, 4z0r:C
12 7aib:C 267 52 0.0370 0.0749 0.3846 0.27 7aic:C
13 6qxz:A 79 44 0.0240 0.1646 0.2955 0.47
14 2l7p:A 100 44 0.0240 0.1300 0.2955 0.58 5yvx:A
15 5jil:A 369 58 0.0240 0.0352 0.2241 0.84 4zxn:A
16 1b63:A 333 45 0.0351 0.0571 0.4222 1.0 1b62:A, 1nhh:A, 1nhi:A, 1nhj:A, 7p8v:A, 7p8v:B
17 3h4l:B 344 49 0.0370 0.0581 0.4082 2.6 3h4l:A
18 4c7w:A 353 37 0.0203 0.0312 0.2973 4.3 4c7w:B
19 4tlx:A 415 63 0.0407 0.0530 0.3492 4.9 4tlx:B, 4tlx:C, 4tlx:D, 4tlz:A, 4tlz:B, 4tlz:C, 4tlz:D, 4tm0:A, 4tm0:B, 4tm0:C, 4tm0:D, 4tm1:A, 4tm1:B, 4tm1:C, 4tm1:D, 4tm3:A, 4tm3:B, 4tm3:C, 4tm3:D, 4tm4:A, 4tm4:B, 4tm4:C, 4tm4:D
20 7rci:A 317 75 0.0425 0.0726 0.3067 7.1 1ea6:A, 1ea6:B, 1h7u:B, 1h7u:A, 7rci:B, 7rck:A, 7rck:B
21 8uu7:q 81 48 0.0351 0.2346 0.3958 7.3 7nhn:r, 8uu4:q, 8uu5:q, 8uu6:q, 8uu8:q, 8uu9:q

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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