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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MAELIPVENLDVVKAIVAEHREVPGCLMQILQETQLKYGYLPLELQGTIADELGIPLTEVYGVATFYSQFTLKPKGKYKI
GICLGTACYVRGSQAIIDKVNSVLGTQVGDTTEDGKWSVDATRCVGACGLAPVMMINEEVFGRLTVDEIPGILEKY

The query sequence (length=156) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8a5e:C 156 156 1.0000 1.0000 1.0000 3.00e-113 7q4v:C, 7q4v:G, 7q4w:C, 7q4w:G
2 7t2r:C 152 150 0.4936 0.5066 0.5133 9.53e-50 7t2r:H
3 8a6t:C 151 149 0.4231 0.4371 0.4430 4.23e-45 8a6t:F, 8bew:C, 8bew:F
4 7p5h:C 156 129 0.4038 0.4038 0.4884 2.19e-39 7p5h:F, 7p5h:c, 7p5h:f, 7p8n:c, 7p8n:C, 7p91:c, 7p91:C, 7p92:C
5 8oh5:A 150 146 0.4167 0.4333 0.4452 1.43e-36 8oh5:D, 8oh5:G, 8oh5:J, 8oh9:A, 8oh9:D, 8oh9:G, 8oh9:J
6 8b9z:E 214 150 0.3718 0.2710 0.3867 4.40e-31 8ba0:E, 8esw:V2, 8esz:V2
7 6tg9:G 148 143 0.3141 0.3311 0.3427 1.21e-28 6tg9:C, 6tga:G, 6tga:C
8 5gup:E 197 150 0.3333 0.2640 0.3467 1.16e-27
9 9fdk:C 160 126 0.2885 0.2812 0.3571 1.55e-27 9fdj:A, 9fdj:C, 9fdk:A, 9fdv:A, 9fdv:C, 9fe0:A, 9fe0:C, 9fe5:A, 9fe5:C, 9fe7:A, 9fe7:C, 9fe8:A, 9fe8:C, 9fea:A, 9fea:C, 9fif:A, 9fif:C, 9fih:A, 9fih:C, 9fii:A, 9fii:C, 9fij:A, 9fij:C, 9fil:A, 9fil:C, 6hl2:A, 6hl2:C, 6hl3:A, 6hl3:C, 6hl4:A, 6hl4:C, 6hla:A, 6hla:C, 6hli:A, 6hli:C, 6hlj:A, 6hlj:C, 6hlm:A, 6hlm:C, 7q5y:E, 7q5y:K, 7q5y:Q, 7q5y:W, 6q9c:A, 6q9c:C, 6q9g:A, 6q9g:C, 6q9j:A, 6q9j:C, 6q9k:A, 6q9k:C, 8qg1:A, 8qg1:C, 8qgw:A, 8qgw:C, 8qh4:A, 8qh4:C, 8qh7:A, 8qh7:C, 8qhk:A, 8qhk:C, 6r7p:A, 6r7p:C, 6saq:A, 6saq:C
10 7awt:E 156 139 0.3397 0.3397 0.3813 9.56e-27 7nyr:E, 7nyu:E, 7nyv:E, 7nz1:E, 7p61:E, 7p62:E, 7p63:E, 7p64:E, 7p69:E, 7p7c:E, 7p7e:E, 7p7j:E, 7p7k:E, 7p7l:E, 7p7m:E, 7z7r:E, 7z7s:E, 7z7t:E, 7z7v:E, 7z80:E, 7z83:E, 7z84:E, 7zc5:E, 7zci:E
11 7v2c:O 217 150 0.3333 0.2396 0.3467 1.00e-26 7ak5:E, 7ak6:E, 7b93:E, 8c2s:E, 8ca3:E, 8ca4:E, 8ca5:E, 7dgq:9, 7dgr:9, 7dgs:9, 7dgz:9, 7dh0:9, 7dkf:92, 6g2j:E, 6g72:E, 5gpn:d, 8iao:E, 8iap:E, 8ib4:E, 8ib5:E, 8ib9:E, 8iba:E, 8ibd:E, 8ibe:E, 8ic2:E, 8ic3:E, 5lc5:E, 5ldw:E, 5ldx:E, 5lnk:2, 5o31:E, 8olt:E, 8om1:E, 7psa:E, 8pw5:2, 8pw6:2, 8pw7:2, 8q0a:E, 8q0f:E, 8q0j:E, 8q0m:E, 8q0o:E, 8q0q:E, 8q1p:E, 8q1u:E, 8q1y:E, 8q25:E, 8q45:E, 8q46:E, 8q47:E, 8q48:E, 8q49:E, 8q4a:E, 6q9d:V2, 6qa9:V2, 6qbx:V2, 6qc2:V2, 6qc3:V2, 6qc4:V2, 6qc5:V2, 6qc6:V2, 6qc7:V2, 6qc8:V2, 6qc9:V2, 6qca:V2, 6qcf:V2, 7qsd:E, 7qsk:E, 7qsl:E, 7qsm:E, 7qsn:E, 7qso:E, 7r41:E, 7r42:E, 7r43:E, 7r44:E, 7r45:E, 7r46:E, 7r47:E, 7r48:E, 7r4c:E, 7r4d:E, 7r4f:E, 7r4g:E, 8rgp:2, 8rgq:2, 8rgr:2, 8rgt:2, 8ud1:1E, 8ueo:1E, 8uep:1E, 8ueq:1E, 8uer:1E, 8ues:1E, 8uet:1E, 8ueu:1E, 8uev:1E, 8uew:1E, 8uex:1E, 8uey:1E, 8uez:1E, 8ugh:1E, 8ugi:1E, 8ugj:1E, 8ugn:1E, 8ugn:5E, 8ugr:1E, 8ugr:5E, 7v2d:O, 7v2e:O, 7v2f:O, 7v2h:O, 7v2k:O, 7v2r:O, 7v30:O, 7v31:O, 7v32:O, 7v33:O, 7v3m:O, 7vb7:O, 7vbn:O, 7vbz:O, 7vwj:O, 7vxp:O, 7vxu:O, 7vy8:O, 7vya:O, 7vyf:O, 7vyh:O, 7vyn:O, 7vz1:O, 7vzv:O, 7vzw:O, 7w00:O, 7w0h:O, 7w0r:O, 7w0y:O, 7w1o:O, 7w1p:O, 7w1t:O, 7w1u:O, 7w1v:O, 7w1z:O, 7w20:O, 7w2k:O, 7w2l:O, 7w2r:O, 7w2u:O, 7w2y:O, 7w31:O, 7w32:O, 7w35:O, 7w4c:O, 7w4d:O, 7w4e:O, 7w4f:O, 7w4g:O, 7w4j:O, 7w4k:O, 7w4l:O, 7w4m:O, 7w4n:O, 7w4q:O, 5xtb:O, 5xtd:O, 5xth:O, 5xti:O, 5xti:BO, 7zd6:2, 7zdh:2, 7zdj:2, 7zdm:2, 7zdp:2, 7zeb:2, 6zk9:2, 6zkc:2, 6zkd:2, 6zke:2, 6zkf:2, 6zkg:2, 6zkh:2, 6zki:2, 6zkj:2, 6zkk:2, 6zkl:2, 6zkm:2, 6zkn:2, 6zko:2, 6zkp:2, 6zkq:2, 6zkr:2, 6zks:2, 6zkt:2, 6zku:2, 6zkv:2, 6zr2:E, 6ztq:E
12 6vw8:C 152 130 0.2885 0.2961 0.3462 1.72e-26 6vw7:A, 6vw7:C, 6vw8:A
13 2auv:A 85 83 0.2372 0.4353 0.4458 6.66e-25
14 8e9g:E 233 130 0.3013 0.2017 0.3615 9.74e-23 8e9h:E, 8e9i:E
15 7b0n:E 216 149 0.3013 0.2176 0.3154 1.64e-22 6gcs:H, 7o6y:H, 7o71:H, 6rfq:H, 6rfr:H, 6rfs:H, 6y79:H, 6yj4:E
16 8b6f:AI 231 158 0.3269 0.2208 0.3228 2.43e-22 8bqs:AI, 8gym:v2, 8gym:V2, 8gzu:v2, 8gzu:V2, 7tgh:V2
17 3iam:2 179 115 0.2628 0.2291 0.3565 9.95e-21 2fug:2, 2fug:B, 2fug:K, 2fug:T, 4hea:2, 4hea:C, 6i0d:2, 6i0d:C, 6i1p:2, 6i1p:C, 3i9v:2, 3i9v:B, 3iam:B, 3ias:2, 3ias:B, 3ias:K, 3ias:T, 3m9s:2, 3m9s:B, 6q8o:2, 6q8o:C, 6q8w:2, 6q8w:C, 6q8x:2, 6q8x:C, 6y11:2, 6y11:C, 2ybb:2, 6ziy:2, 6zjl:2, 6zjn:2, 6zjy:2
18 7zmb:H 221 131 0.2692 0.1900 0.3206 1.24e-18 7zm7:H, 7zmg:H
19 8iuf:V2 225 100 0.2372 0.1644 0.3700 1.63e-16 8j9h:V2, 8j9i:V2, 8j9j:V2
20 8e73:V2 222 98 0.2308 0.1622 0.3673 1.90e-16 6x89:V2
21 7arc:E 235 102 0.2308 0.1532 0.3529 1.10e-15 7ard:E
22 7a23:B 219 102 0.2372 0.1689 0.3627 2.29e-15 7a24:B, 7aqr:E, 7ar7:E, 7ar8:E, 7arb:E, 8bed:E, 8bpx:E, 8bq5:E, 8bq6:E
23 8qby:E 236 157 0.2821 0.1864 0.2803 2.50e-15
24 7p8n:a 642 77 0.1667 0.0405 0.3377 5.49e-07 7p5h:A, 7p5h:D, 7p5h:a, 7p5h:d, 7p8n:A, 7p91:a, 7p91:A, 7p92:A
25 5xfa:A 581 138 0.2308 0.0620 0.2609 5.72e-07 5xf9:A, 5xf9:E, 5xfa:E
26 7vw6:B 560 138 0.2051 0.0571 0.2319 4.57e-06 7e5z:B, 8j83:B, 7xqw:B
27 7q4v:B 599 83 0.1538 0.0401 0.2892 0.097 8a5e:B, 7q4v:F, 7q4w:B, 7q4w:F
28 6c66:B 334 70 0.1474 0.0689 0.3286 0.19
29 8a6t:B 630 67 0.1410 0.0349 0.3284 1.8 8a6t:E, 8bew:B, 8bew:E
30 6c66:C 367 78 0.1538 0.0654 0.3077 3.8 6c66:D, 6c66:E, 6c66:F, 5u07:E, 5u07:F, 5u07:G, 5u07:H, 5u0a:E, 5u0a:F, 5u0a:G, 5u0a:H
31 3n92:A 550 39 0.0962 0.0273 0.3846 3.9 3n98:A
32 6c66:H 329 78 0.1538 0.0729 0.3077 4.2 5u07:I, 5u0a:I
33 3wky:A 655 47 0.1218 0.0290 0.4043 5.9 3wky:B
34 7lg5:A 871 38 0.0833 0.0149 0.3421 6.4 7lg5:B, 7lg5:C, 7lg5:D, 7lgj:A, 7lgj:B, 7lgj:C, 7lgj:D, 7lgq:A, 7lgq:B, 7lgq:C, 7lgq:D, 7txu:A, 7txu:B, 7txu:C, 7txu:D, 7txv:A, 7txv:B, 7txv:C, 7txv:D
35 1f37:B 110 76 0.1282 0.1818 0.2632 9.5 1f37:A, 1m2a:A, 1m2a:B, 1m2b:A, 1m2b:B, 1m2d:A, 1m2d:B
36 3ef1:A 372 73 0.1090 0.0457 0.2329 9.7 3ef0:A, 4xpz:A, 4xq0:A
37 3bq1:A 344 94 0.1538 0.0698 0.2553 9.8 3bq0:A, 3bq2:A, 4f4y:B, 4f4y:A, 4hyk:A, 4nlg:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218