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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MADPETAAKFKSKNAFPDPLNDPKCNPKSLVKKYLTPKVFESLKNKKTKLGITLWDCINSGVVNLDSGVGVYAGDEESYT
LFGPLFDAIIEDYHSPYKLATGHNSDMNPAHVKAPDLDPANRYIRSTRIRVARSLKGYGLAPGVTKAHRLEIEKKVVGVL
TSLTGDLAGKYYPLSGMDEKTRQQLVDDHFLFKKGDRFLEAAGINKEWPEGRGIYHNNDKTFLVWLNEEDHLRIISMEKG
SDIGSVFSRLCRAVNEIDKKLGFQHTKKHGYLTSCPSNLGTGMRASVHVKIPHAKEHPDFENILTKYHIQARGIDAGVYD
ISNRRRLGLSEVQCVQDMYDGVKALMELEKEAIAKKRSVFPEVLKNPEVKSLLRKYLTPELFDSLKDKKTAKGISLYDCI
NSGVENLDSSCGVYAGDEECYTLFAPLFDKIVEDYHSPYKLANKHTSDMNPEKVDAPNLDPEGTYIRSTRIRVARNVKGY
ALTPGLTRNERLDIERKVVGVLSSLTGDLAGQYYPLTGMDEATRQKLVNDHFLFKKGDRFLEAAGVNKLWPEGRGIFHNN
DKTFLVWINEEDQLRIISMEKGSDIGSVFGRLCRAVNEIDKQLGFQHTDAHGYLSGCPTNLGTGMRASVHVKIPKASAHP
DFQKICDEFHIQARGIGVFDISNRRRLGLSEVQCVQDMYNGVKKLLEIEKST

The query sequence (length=692) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4rf7:B 700 701 0.9971 0.9857 0.9843 0.0 4rf7:A, 4rf8:A, 4rf8:B, 4rf9:A, 4rf9:B
2 4woe:A 716 699 0.4350 0.4204 0.4306 0.0 4wod:A, 4woe:B
3 4woe:A 716 333 0.2153 0.2081 0.4474 3.59e-87 4wod:A, 4woe:B
4 4bg4:A 356 349 0.2616 0.5084 0.5186 4.37e-125 4bg4:B, 4bhl:A
5 4bg4:A 356 333 0.2616 0.5084 0.5435 7.61e-124 4bg4:B, 4bhl:A
6 1bg0:A 356 333 0.2601 0.5056 0.5405 1.40e-121 4gvy:A, 4gvz:A, 4gw0:A, 4gw2:A, 5j99:A, 5j9a:A, 1m15:A, 1p50:A, 1p52:A, 1rl9:A, 1sd0:A
7 1bg0:A 356 354 0.2486 0.4831 0.4859 1.19e-117 4gvy:A, 4gvz:A, 4gw0:A, 4gw2:A, 5j99:A, 5j9a:A, 1m15:A, 1p50:A, 1p52:A, 1rl9:A, 1sd0:A
8 5u92:A 347 327 0.2558 0.5101 0.5413 6.57e-121
9 5u92:A 347 345 0.2457 0.4899 0.4928 6.59e-118
10 6ky3:A 353 341 0.2471 0.4844 0.5015 3.74e-115
11 6ky3:A 353 328 0.2471 0.4844 0.5213 4.58e-114
12 1u6r:A 380 368 0.2457 0.4474 0.4620 5.19e-98 2crk:A, 1u6r:B
13 1u6r:A 380 338 0.2211 0.4026 0.4527 7.16e-92 2crk:A, 1u6r:B
14 3ju5:C 367 355 0.2298 0.4332 0.4479 7.26e-96 3ju5:A, 3ju6:A
15 3ju5:C 367 335 0.2168 0.4087 0.4478 5.45e-93 3ju5:A, 3ju6:A
16 1vrp:B 374 338 0.2269 0.4198 0.4645 7.87e-95 1vrp:A
17 1vrp:B 374 351 0.2197 0.4064 0.4330 5.01e-92 1vrp:A
18 1qh4:D 380 347 0.2240 0.4079 0.4467 4.44e-92 3b6r:B, 3drb:B, 7tun:A, 7tun:B
19 1qh4:D 380 338 0.2110 0.3842 0.4320 1.54e-88 3b6r:B, 3drb:B, 7tun:A, 7tun:B
20 4z9m:C 375 365 0.2225 0.4107 0.4219 1.20e-89 4z9m:A, 4z9m:B, 4z9m:D, 4z9m:E, 4z9m:F, 4z9m:G, 4z9m:H
21 4z9m:C 375 355 0.2124 0.3920 0.4141 5.75e-87 4z9m:A, 4z9m:B, 4z9m:D, 4z9m:E, 4z9m:F, 4z9m:G, 4z9m:H
22 3jq3:A 364 367 0.2153 0.4093 0.4060 1.66e-84
23 3jq3:A 364 337 0.1936 0.3681 0.3976 5.88e-80
24 4v7n:BB 388 379 0.2182 0.3892 0.3984 3.77e-82 4v7n:AA, 4v7n:AB, 4v7n:AC, 4v7n:AD, 4v7n:AE, 4v7n:AF, 4v7n:AG, 4v7n:AH, 4v7n:AI, 4v7n:AJ, 4v7n:AK, 4v7n:AL, 4v7n:AM, 4v7n:AN, 4v7n:AO, 4v7n:AP, 4v7n:AQ, 4v7n:AR, 4v7n:BA, 4v7n:BC, 4v7n:BD, 4v7n:BE, 4v7n:BF, 4v7n:BG, 4v7n:BH, 4v7n:BI, 4v7n:BJ, 4v7n:BK, 4v7n:BL, 4v7n:BM, 4v7n:BN, 4v7n:BO, 4v7n:BP, 4v7n:BQ, 4v7n:BR
25 4v7n:BB 388 359 0.2052 0.3660 0.3955 1.02e-77 4v7n:AA, 4v7n:AB, 4v7n:AC, 4v7n:AD, 4v7n:AE, 4v7n:AF, 4v7n:AG, 4v7n:AH, 4v7n:AI, 4v7n:AJ, 4v7n:AK, 4v7n:AL, 4v7n:AM, 4v7n:AN, 4v7n:AO, 4v7n:AP, 4v7n:AQ, 4v7n:AR, 4v7n:BA, 4v7n:BC, 4v7n:BD, 4v7n:BE, 4v7n:BF, 4v7n:BG, 4v7n:BH, 4v7n:BI, 4v7n:BJ, 4v7n:BK, 4v7n:BL, 4v7n:BM, 4v7n:BN, 4v7n:BO, 4v7n:BP, 4v7n:BQ, 4v7n:BR
26 6fh2:A 353 251 0.0882 0.1728 0.2430 2.10e-12 6fh3:A, 6fh3:B
27 6fh2:A 353 246 0.0838 0.1643 0.2358 2.36e-12 6fh3:A, 6fh3:B
28 4nh2:F 364 56 0.0260 0.0495 0.3214 1.6 4nh2:A
29 1u7c:A 383 56 0.0260 0.0470 0.3214 1.7 6b21:A, 4nh2:C, 4nh2:D, 4nh2:E, 4nh2:B, 1u7g:A
30 7zi4:C 447 146 0.0506 0.0783 0.2397 2.0 9c57:E, 9c57:C, 9c57:A, 9c62:C, 9c62:E, 9c62:A, 6hts:A, 6hts:C, 6hts:E, 5oaf:A, 5oaf:C, 5oaf:E, 8x15:M, 8x15:O, 8x15:Q, 8x19:M, 8x19:O, 8x19:Q, 8x1c:M, 8x1c:O, 8x1c:Q, 8xvg:A, 8xvg:C, 8xvg:E, 8xvt:A, 8xvt:C, 8xvt:E, 7zi4:A, 7zi4:E
31 7ole:C 427 129 0.0520 0.0843 0.2791 2.7 7ole:E
32 8gj5:B 257 58 0.0231 0.0623 0.2759 3.3 8gj5:A, 8gj5:C, 8gjf:A, 8gjf:B, 8gjf:C
33 2c9o:A 398 125 0.0520 0.0905 0.2880 3.9 2c9o:B
34 7a9w:A 513 99 0.0448 0.0604 0.3131 5.2 7a9x:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218