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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEK
LSVRNHGFPLLTVYLKVFLSPGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPV
QFLCPNISVAYRLLGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHEVVMVPFPVTVYDEDDSAPTFPAGVDTASA
VVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRN
LSISENRTMQLAVLVNDSGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSCST
LGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEEC
GGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNC
FPEEEKCFCEP

The query sequence (length=571) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6q2o:E 572 575 0.9947 0.9930 0.9878 0.0 6q2j:E, 6q2j:F, 6q2o:F, 6q2r:E, 6q2r:F, 6q2r:Y, 6q2r:Z, 6q2s:E, 6q2s:F, 4ux8:A, 4ux8:B
2 6q2n:E 553 572 0.9667 0.9982 0.9650 0.0 6q2n:F
3 7aml:A 596 606 0.4378 0.4195 0.4125 7.53e-146 7amk:A, 7amk:B, 7aml:D
4 8egx:B 425 172 0.0806 0.1082 0.2674 0.004 8egw:B
5 8d40:B 427 243 0.1033 0.1382 0.2428 0.11 8d40:A
6 8egx:A 421 46 0.0368 0.0499 0.4565 0.16 8egw:A
7 3d34:B 215 104 0.0543 0.1442 0.2981 0.35 3d34:A
8 4lp7:D 230 148 0.0613 0.1522 0.2365 0.45 4lp7:A, 4lp7:B, 4lp7:C
9 5szr:A 424 82 0.0333 0.0448 0.2317 1.2 5szr:B, 5szr:C
10 3p41:A 283 77 0.0473 0.0954 0.3506 1.5 3lsn:A
11 5szn:A 523 49 0.0298 0.0325 0.3469 1.6
12 5tpk:A 202 89 0.0473 0.1337 0.3034 2.2
13 6e6b:A 633 79 0.0333 0.0300 0.2405 2.4 6e6b:B
14 5t9t:A 526 51 0.0210 0.0228 0.2353 3.0 5t9t:B
15 5v5x:D 427 82 0.0333 0.0445 0.2317 3.5 5v5x:A, 5v5x:B, 5v5x:C
16 1npi:A 61 36 0.0210 0.1967 0.3333 4.3
17 6vg1:A 642 55 0.0350 0.0312 0.3636 4.5 6vg1:B
18 3mvs:A 210 55 0.0315 0.0857 0.3273 4.8 4apx:A, 4aq8:A, 4aq8:B, 4aqa:A, 4aqe:A, 4axw:A, 6n2e:C, 6n2e:D, 7sb6:A, 7sb6:B, 7sb6:C, 2wbx:A, 2wcp:A, 2wd0:A, 2wd0:C, 2whv:A, 4xxw:C, 4xxw:D
19 8tri:C 419 59 0.0350 0.0477 0.3390 5.0
20 8tri:B 454 59 0.0350 0.0441 0.3390 5.2 7suu:A, 7suu:B, 8tri:A
21 8gna:A 1188 45 0.0280 0.0135 0.3556 8.7
22 2o2y:C 293 65 0.0280 0.0546 0.2462 9.0 3am3:A, 3am3:B, 3am4:A, 3am4:B, 3am5:A, 3am5:B, 2foi:A, 2foi:C, 2foi:B, 2foi:D, 4ige:A, 4ige:B, 4igf:A, 4igf:B, 3lsy:A, 3lsy:B, 3lt0:A, 3lt0:B, 3lt1:A, 3lt1:B, 3lt2:A, 3lt2:B, 3lt4:A, 3lt4:B, 1nhg:A, 1nhg:B, 1nhw:A, 1nhw:B, 1nnu:A, 1nnu:B, 2nq8:A, 2nq8:C, 2nq8:B, 2nq8:D, 2o2y:A, 2o2y:B, 2o2y:D, 2ol4:A, 2ol4:B, 2oos:A, 2oos:B, 2op0:B, 2op1:A, 2op1:B, 1uh5:A, 1uh5:B, 1v35:A, 1v35:B, 1vrw:A, 1vrw:B, 1zsn:A, 1zsn:B, 1zw1:A, 1zw1:B, 1zxb:A, 1zxb:B, 1zxl:A, 1zxl:B
23 7u71:AAA 300 58 0.0333 0.0633 0.3276 9.1 5wj8:A
24 5dzw:A 417 112 0.0560 0.0767 0.2857 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218