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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEK
LSVRNHGFPLLTVYLKVFLSCQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFL
CPNISVAYRLLGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHEEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVV
EFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLS
ISENRTMQLAVLVNDSGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCS
TLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEE
CGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCN
CFPEEEKCFCEP

The query sequence (length=572) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6q2o:E 572 572 1.0000 1.0000 1.0000 0.0 6q2j:E, 6q2j:F, 6q2o:F, 6q2r:E, 6q2r:F, 6q2r:Y, 6q2r:Z, 6q2s:E, 6q2s:F, 4ux8:A, 4ux8:B
2 6q2n:E 553 574 0.9633 0.9964 0.9599 0.0 6q2n:F
3 7aml:A 596 606 0.4353 0.4178 0.4109 1.93e-146 7amk:A, 7amk:B, 7aml:D
4 8egx:B 425 177 0.0839 0.1129 0.2712 0.003 8egw:B
5 6vft:C 420 251 0.1154 0.1571 0.2629 0.003 6vft:A, 6vft:B, 6vft:D
6 8d40:B 427 249 0.1031 0.1382 0.2369 0.047 8d40:A
7 5szr:A 424 79 0.0315 0.0425 0.2278 0.10 5szr:B, 5szr:C
8 5tpk:A 202 89 0.0490 0.1386 0.3146 0.14
9 8egx:A 421 47 0.0350 0.0475 0.4255 0.23 8egw:A
10 5v5x:D 427 79 0.0315 0.0422 0.2278 0.30 5v5x:A, 5v5x:B, 5v5x:C
11 3mvs:A 210 55 0.0315 0.0857 0.3273 0.32 4apx:A, 4aq8:A, 4aq8:B, 4aqa:A, 4aqe:A, 4axw:A, 6n2e:C, 6n2e:D, 7sb6:A, 7sb6:B, 7sb6:C, 2wbx:A, 2wcp:A, 2wd0:A, 2wd0:C, 2whv:A, 4xxw:C, 4xxw:D
12 6pgw:A 427 181 0.0857 0.1148 0.2707 0.74 5co1:A, 5co1:B, 5co1:C, 5co1:D
13 6e6b:A 633 78 0.0315 0.0284 0.2308 0.94 6e6b:B
14 5szn:A 523 52 0.0315 0.0344 0.3462 1.3
15 6vg1:A 642 56 0.0367 0.0327 0.3750 1.5 6vg1:B
16 5t9t:A 526 49 0.0227 0.0247 0.2653 3.3 5t9t:B
17 3d34:B 215 105 0.0524 0.1395 0.2857 3.6 3d34:A
18 1npi:A 61 36 0.0210 0.1967 0.3333 4.3
19 4lp7:D 230 148 0.0594 0.1478 0.2297 4.6 4lp7:A, 4lp7:B, 4lp7:C
20 8tri:B 454 59 0.0350 0.0441 0.3390 4.7 7suu:A, 7suu:B, 8tri:A
21 8tri:C 419 59 0.0350 0.0477 0.3390 5.0
22 7u71:AAA 300 58 0.0315 0.0600 0.3103 5.4 5wj8:A
23 5i8d:A 335 278 0.1171 0.2000 0.2410 7.3 5tfk:A, 5ulu:A, 5un2:A
24 8gna:A 1188 45 0.0280 0.0135 0.3556 8.2
25 5dzw:A 417 112 0.0577 0.0791 0.2946 8.3
26 7cym:B 418 44 0.0332 0.0455 0.4318 10.0 7cym:A, 7ev1:A, 7ev1:B, 6ulm:B, 6ulm:A
27 5ah5:A 789 38 0.0227 0.0165 0.3421 10.0 5ah5:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218