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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
LYFQGHMEGVRWAFSCGTWLPSRAEWLLAVRSIQPEEKERIGQFVFARDAKAAMAGRLMIRKLVAEKLNIPWNHIRLQRT
AKGKPVLAKDNPYPNFNFNISHQGDYAVLAAEPELQVGIDIMKTSFPGRGSIPEFFHIMKRKFTNKEWETIRSFKDEWTQ
LDMFYRNWALKESFIKAIGVGLGFELQRLEFDLSPLNLDIGQVYKETRLFLDGEEEKEWAFEESKIDEHHFVAVALRKPT
QRQFTILNFNDLMSSAVPMTPEDPSFWDCFCFTEEIPIRN

The query sequence (length=280) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2c43:A 280 280 1.0000 1.0000 1.0000 0.0 2cg5:A
2 1qr0:A 228 161 0.1857 0.2281 0.3230 4.05e-19 4mrt:A
3 5a0y:A 548 110 0.0857 0.0438 0.2182 0.025 5a0y:D, 5a8k:A, 5a8k:D, 7b2h:A, 7b2h:D, 5g0r:A, 5g0r:D, 1hbm:A, 1hbm:D, 1hbn:A, 1hbn:D, 1hbo:A, 1hbo:D, 1hbu:A, 1hbu:D, 3m1v:A, 3m1v:D, 3m2r:A, 3m2r:D, 3m2u:A, 3m2u:D, 3m2v:A, 3m2v:D, 3m30:A, 3m30:D, 3m32:A, 3m32:D, 1mro:A, 1mro:D, 3pot:A, 3pot:D, 7suc:A, 7suc:a, 7sxm:A, 7sxm:D
4 7nkg:D 565 40 0.0464 0.0230 0.3250 0.14 7nkg:A, 7nkg:G, 7nkg:J
5 1fth:A 117 68 0.0893 0.2137 0.3676 0.16 1fth:B, 1fth:C
6 1e6v:A 545 99 0.0821 0.0422 0.2323 0.16 1e6v:D
7 4id9:B 328 94 0.0893 0.0762 0.2660 0.24 4id9:A, 4idg:A, 4idg:B
8 1e6y:A 568 72 0.0786 0.0387 0.3056 1.1 1e6y:D, 8gf5:A, 8gf5:B
9 5n1q:A 549 29 0.0393 0.0200 0.3793 1.1 5n1q:D, 5n28:A, 5n28:D, 5n2a:A
10 2vdv:E 216 54 0.0679 0.0880 0.3519 2.0 2vdv:F
11 3hyk:A 117 56 0.0607 0.1453 0.3036 2.4 3hyk:B, 3hyk:C
12 8xr6:V 137 84 0.0679 0.1387 0.2262 2.5 8wb4:V, 8wb4:v, 8xr6:v
13 8aht:A 140 44 0.0571 0.1143 0.3636 2.8 8aht:B
14 5xuk:A 115 54 0.0714 0.1739 0.3704 3.0
15 5a8w:D 549 26 0.0393 0.0200 0.4231 3.2 5a8r:A, 5a8r:D, 5a8r:G, 5a8r:J, 5a8w:A, 5a8w:G, 5a8w:J
16 7xn7:m 1187 98 0.0857 0.0202 0.2449 3.2 7xse:m, 7xsx:m, 7xsz:m, 7xt7:m, 7xtd:m, 7xti:m
17 3sqg:A 578 105 0.0893 0.0433 0.2381 3.6 3sqg:D, 3sqg:G
18 7a5f:33 95 43 0.0357 0.1053 0.2326 6.3 7a5g:33, 7a5h:3, 7a5i:33, 7a5j:3, 7a5k:33, 5aj4:B8, 8any:3, 4ce4:8, 6gaw:B8, 6gb2:B8, 6i9r:3, 3j7y:3, 3j9m:3, 8k2a:Li, 8k2b:Li, 7l08:3, 7l20:3, 7nqh:B8, 7nql:B8, 7nsh:B8, 7nsi:B8, 7nsj:B8, 6nu2:3, 6nu3:3, 7o9k:3, 7o9m:3, 7odr:3, 7ods:3, 7odt:3, 7of0:3, 7of2:3, 7of3:3, 7of4:3, 7of5:3, 7of6:3, 7of7:3, 7og4:3, 7oi7:3, 7oi8:3, 7oi9:3, 7oia:3, 7oib:3, 7oic:3, 7oid:3, 7oie:3, 8oin:BK, 8oiq:BK, 8oir:BK, 8oit:BK, 5ool:3, 5oom:3, 7pd3:3, 8pk0:3, 7po4:3, 7qh6:3, 7qh7:3, 7qi4:3, 7qi5:3, 7qi6:3, 8qsj:3, 8qu1:3, 8qu5:3, 4v19:8, 6vlz:3, 6vmi:3, 8xt0:Li, 8xt1:Li, 8xt2:Li, 8xt3:Li, 6ydp:B8, 6ydw:B8, 6zm5:3, 6zm6:3, 6zs9:3, 6zsa:3, 6zsb:3, 6zsc:3, 6zsd:3, 6zse:3, 6zsg:3
19 7b1s:D 593 34 0.0429 0.0202 0.3529 7.3 7b1s:A, 7b2c:A, 7b2c:D
20 4dem:F 346 69 0.0643 0.0520 0.2609 9.5 3b7l:A, 5cg5:A, 5cg6:A, 3cp6:A, 5dgm:F, 5dgn:F, 5dgs:F, 5diq:F, 5djp:F, 5djr:F, 5djv:F, 2f7m:F, 2f89:F, 2f8c:F, 2f8z:F, 2f92:F, 2f94:F, 2f9k:F, 4ga3:A, 4h5c:F, 4h5d:F, 4h5e:F, 5ja0:F, 5juz:F, 4jvj:F, 5jv0:F, 5jv1:F, 5jv2:F, 4kfa:A, 4kpd:A, 4kpj:A, 4kq5:A, 4kqs:A, 4kqu:A, 5ksx:F, 4l2x:F, 4lfv:F, 4lpg:F, 4lph:F, 3n1v:F, 3n1w:F, 4n1z:F, 3n3l:F, 3n45:F, 3n46:F, 3n49:F, 3n5h:F, 3n5j:F, 3n6k:F, 6n7y:F, 6n7z:F, 6n82:F, 6n83:F, 4n9u:A, 4nfi:F, 4nfj:F, 4nfk:F, 4ng6:A, 4nke:A, 4nkf:A, 4nua:A, 6oag:F, 6oah:F, 4ogu:A, 2opm:A, 2opn:A, 4p0v:A, 4p0w:A, 4p0x:A, 4pvx:F, 4pvy:F, 4q23:A, 2qis:A, 4qpf:A, 4qxs:F, 2rah:A, 4rxa:A, 3rye:A, 3s4j:A, 2vf6:A, 5ygi:A, 1yq7:A, 1yv5:A, 1zw5:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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